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The map label for this gene is yfkJ [H]

Identifier: 57238130

GI number: 57238130

Start: 1308976

End: 1309431

Strand: Direct

Name: yfkJ [H]

Synonym: CJE1394

Alternate gene names: 57238130

Gene position: 1308976-1309431 (Clockwise)

Preceding gene: 57238128

Following gene: 57238131

Centisome position: 73.63

GC content: 30.92

Gene sequence:

>456_bases
ATGAAAAAAATACTCTTTATATGTTTAGGCAATATATGCCGTTCGCCTATGGCAGAATTTATCATGAAAGATCTTATCAA
AAAAGCAAATTTAGAAAAAGAATTTTTTATAAGTAGTGCTGGAACTTCAGGAGAACACGATGGAGAAGGTATGCACTATG
GCACCAAAAACAAGCTTACTCAACTTAACATAGAACACAAAAACTTCACAAGCAAAAAACTCACTCAAAAGCTTTGCGAT
GAAAGCGATTTTTTAATCACCATGGACAATTCTAACTTCAAAAATGTTTTAAAAAACTTCACCAACACCCAAAACAAAGT
TTTAAAAATCACTGATTTTAGCCCTAGTCTAAACTACGATGAAGTCCCTGATCCTTGGTATAGTGGGAATTTTGATGAAA
CTTATAAAATTTTATCCCTAGCTTGTAAAAATTTACTTGTTTTTTTATCAAAATAA

Upstream 100 bases:

>100_bases
AAAACACCAAACCAACACACAAGCAAAGTTCTATTGAAATTTTCCATGGATTTATTGTATGATATTTTTTATAATTTTTA
ATTAAAACTCAAGGATAAAA

Downstream 100 bases:

>100_bases
TTTAAAACAACTATATATTACTTCTTGTTTACTTTTTAGGCTTATACTTCTAAACGAACCGAAAAACATTCATAAGAAAA
ACTCCTTAAAATTACACGCC

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKKILFICLGNICRSPMAEFIMKDLIKKANLEKEFFISSAGTSGEHDGEGMHYGTKNKLTQLNIEHKNFTSKKLTQKLCD
ESDFLITMDNSNFKNVLKNFTNTQNKVLKITDFSPSLNYDEVPDPWYSGNFDETYKILSLACKNLLVFLSK

Sequences:

>Translated_151_residues
MKKILFICLGNICRSPMAEFIMKDLIKKANLEKEFFISSAGTSGEHDGEGMHYGTKNKLTQLNIEHKNFTSKKLTQKLCD
ESDFLITMDNSNFKNVLKNFTNTQNKVLKITDFSPSLNYDEVPDPWYSGNFDETYKILSLACKNLLVFLSK
>Mature_151_residues
MKKILFICLGNICRSPMAEFIMKDLIKKANLEKEFFISSAGTSGEHDGEGMHYGTKNKLTQLNIEHKNFTSKKLTQKLCD
ESDFLITMDNSNFKNVLKNFTNTQNKVLKITDFSPSLNYDEVPDPWYSGNFDETYKILSLACKNLLVFLSK

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=152, Percent_Identity=26.9736842105263, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325330, Length=149, Percent_Identity=36.9127516778523, Blast_Score=78, Evalue=7e-16,
Organism=Drosophila melanogaster, GI78706770, Length=147, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706772, Length=147, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI78706766, Length=150, Percent_Identity=28, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI78706768, Length=150, Percent_Identity=28, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17307; Mature: 17307

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILFICLGNICRSPMAEFIMKDLIKKANLEKEFFISSAGTSGEHDGEGMHYGTKNKLT
CCCEEEEHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCCCCCCEE
QLNIEHKNFTSKKLTQKLCDESDFLITMDNSNFKNVLKNFTNTQNKVLKITDFSPSLNYD
EEECCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCC
EVPDPWYSGNFDETYKILSLACKNLLVFLSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKILFICLGNICRSPMAEFIMKDLIKKANLEKEFFISSAGTSGEHDGEGMHYGTKNKLT
CCCEEEEHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEECCCCCCCCCCCCCCCCCCCCEE
QLNIEHKNFTSKKLTQKLCDESDFLITMDNSNFKNVLKNFTNTQNKVLKITDFSPSLNYD
EEECCCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCC
EVPDPWYSGNFDETYKILSLACKNLLVFLSK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]