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The map label for this gene is waaC [H]

Identifier: 57238014

GI number: 57238014

Start: 1192544

End: 1193572

Strand: Direct

Name: waaC [H]

Synonym: CJE1275

Alternate gene names: 57238014

Gene position: 1192544-1193572 (Clockwise)

Preceding gene: 57237995

Following gene: 57238015

Centisome position: 67.08

GC content: 29.35

Gene sequence:

>1029_bases
ATGAAAATAGCAATTGTTCGTTTGTCAGCACTTGGTGATATTATCCAAAGTGCCGTGGTTTTGCAATTTATCAAAAATTT
TAAAAAAGATATAGAAATTCATTGGTTTGTAGATGAAAAATTTGAAGGCATACTTAAAAACCATCCTTTAATAGACAAAC
TCTATGCCCTGCCCTTAAAAGACAAAAAAATTTTAAAAAGCCTAAAAATTCTTCTTAAAGCAAGAAAAAACAACTATAAT
GCAGTAATAGATCTACAAGGGCTTATAAAATCTGCTATTGTAAGTCGAATTTTAAGTAGAAATAATTTTGGTTTTGATAA
AAATAGTCTTAAAGAAAGTTTTGCTCATAATTTCTACAACCAAAAACTTGAGTTAGATTACAATGAAAATGTATTTGTAA
GATACTTAAGTCTTACCTCCTTTATGTTAAATACTGATTTTAATGTCAAAAATTTAGCCTTTAAACAAGATATTTTTAGC
GTAGATGAAAATTTAAAACAATTCTTAAACAATAAACTCAAGCTCGACAAAAACGAAAAAAACATACTCATACACGTGGG
TTCAAGTGTAGAAAATAAAATCTATCCTAAAACCAAACTTGCTATACTTTGCAAACTTTTAATCAATGAATTTCAACAAG
CAAAAATTTGGCTCGCTTGGGGAAATGTAAAAGAATACGAATTTGCCAAAGAGGTTTTAAATCTTAGTGGTATTGATGAA
ACACATATAGAATTAGCACCAAAATTCAGCCTTGAAGAGCTAATGGCTTTTACAAAAATGATGAATCTTATCATAGGAAA
TGATAGTGGTCCAACACATTTGGCTTTTGCTTTAAATAAGGCATCTATTACGATTTTTGGTGCAACACCAAGCTACCGCA
ATGCTTTTCAAACTCATATCAATAAAATCATTGATGCAGGTAAAAAAATCCAAAATGCCAAGCATATCGATAAAAGTGAT
TTTTGTATCACGCGTATAGAAGAAGAAGATATCTTCAAACTTGCCAAAGGCTTACTTAATGAAAAATAG

Upstream 100 bases:

>100_bases
CAAAAACACAAATATAACCTTCATTTTTTGCCATTTTTTAACCTTTTTTTAAATAATTTCGCTAAAATCATAGCAAAAAT
TTTAAAATATTAGGCTTTTA

Downstream 100 bases:

>100_bases
TGATAGAATATATCTTAGTCTTTATTATATTTTGAAATTTTTTGTTACTTTTATGCCTGAGTGTATCTTGCATTTTTTAG
CTTTAATTGTAGCAAGAATC

Product: lipopolysaccharide heptosyltransferase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKIAIVRLSALGDIIQSAVVLQFIKNFKKDIEIHWFVDEKFEGILKNHPLIDKLYALPLKDKKILKSLKILLKARKNNYN
AVIDLQGLIKSAIVSRILSRNNFGFDKNSLKESFAHNFYNQKLELDYNENVFVRYLSLTSFMLNTDFNVKNLAFKQDIFS
VDENLKQFLNNKLKLDKNEKNILIHVGSSVENKIYPKTKLAILCKLLINEFQQAKIWLAWGNVKEYEFAKEVLNLSGIDE
THIELAPKFSLEELMAFTKMMNLIIGNDSGPTHLAFALNKASITIFGATPSYRNAFQTHINKIIDAGKKIQNAKHIDKSD
FCITRIEEEDIFKLAKGLLNEK

Sequences:

>Translated_342_residues
MKIAIVRLSALGDIIQSAVVLQFIKNFKKDIEIHWFVDEKFEGILKNHPLIDKLYALPLKDKKILKSLKILLKARKNNYN
AVIDLQGLIKSAIVSRILSRNNFGFDKNSLKESFAHNFYNQKLELDYNENVFVRYLSLTSFMLNTDFNVKNLAFKQDIFS
VDENLKQFLNNKLKLDKNEKNILIHVGSSVENKIYPKTKLAILCKLLINEFQQAKIWLAWGNVKEYEFAKEVLNLSGIDE
THIELAPKFSLEELMAFTKMMNLIIGNDSGPTHLAFALNKASITIFGATPSYRNAFQTHINKIIDAGKKIQNAKHIDKSD
FCITRIEEEDIFKLAKGLLNEK
>Mature_342_residues
MKIAIVRLSALGDIIQSAVVLQFIKNFKKDIEIHWFVDEKFEGILKNHPLIDKLYALPLKDKKILKSLKILLKARKNNYN
AVIDLQGLIKSAIVSRILSRNNFGFDKNSLKESFAHNFYNQKLELDYNENVFVRYLSLTSFMLNTDFNVKNLAFKQDIFS
VDENLKQFLNNKLKLDKNEKNILIHVGSSVENKIYPKTKLAILCKLLINEFQQAKIWLAWGNVKEYEFAKEVLNLSGIDE
THIELAPKFSLEELMAFTKMMNLIIGNDSGPTHLAFALNKASITIFGATPSYRNAFQTHINKIIDAGKKIQNAKHIDKSD
FCITRIEEEDIFKLAKGLLNEK

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=302, Percent_Identity=26.8211920529801, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.-.-.- [C]

Molecular weight: Translated: 39328; Mature: 39328

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIVRLSALGDIIQSAVVLQFIKNFKKDIEIHWFVDEKFEGILKNHPLIDKLYALPLK
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCHHHHHHHCCCC
DKKILKSLKILLKARKNNYNAVIDLQGLIKSAIVSRILSRNNFGFDKNSLKESFAHNFYN
HHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
QKLELDYNENVFVRYLSLTSFMLNTDFNVKNLAFKQDIFSVDENLKQFLNNKLKLDKNEK
CEEEECCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
NILIHVGSSVENKIYPKTKLAILCKLLINEFQQAKIWLAWGNVKEYEFAKEVLNLSGIDE
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHCCCCCC
THIELAPKFSLEELMAFTKMMNLIIGNDSGPTHLAFALNKASITIFGATPSYRNAFQTHI
HHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHH
NKIIDAGKKIQNAKHIDKSDFCITRIEEEDIFKLAKGLLNEK
HHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIAIVRLSALGDIIQSAVVLQFIKNFKKDIEIHWFVDEKFEGILKNHPLIDKLYALPLK
CEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCCHHHHHHHCCCC
DKKILKSLKILLKARKNNYNAVIDLQGLIKSAIVSRILSRNNFGFDKNSLKESFAHNFYN
HHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
QKLELDYNENVFVRYLSLTSFMLNTDFNVKNLAFKQDIFSVDENLKQFLNNKLKLDKNEK
CEEEECCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
NILIHVGSSVENKIYPKTKLAILCKLLINEFQQAKIWLAWGNVKEYEFAKEVLNLSGIDE
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHCCCCCC
THIELAPKFSLEELMAFTKMMNLIIGNDSGPTHLAFALNKASITIFGATPSYRNAFQTHI
HHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCEEEEEECCCHHHHHHHHHH
NKIIDAGKKIQNAKHIDKSDFCITRIEEEDIFKLAKGLLNEK
HHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Glycosyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8478319; 8041620; 9278503; 1624462 [H]