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The map label for this gene is livH [H]

Identifier: 57237904

GI number: 57237904

Start: 1078104

End: 1079000

Strand: Reverse

Name: livH [H]

Synonym: CJE1161

Alternate gene names: 57237904

Gene position: 1079000-1078104 (Counterclockwise)

Preceding gene: 57237905

Following gene: 57237903

Centisome position: 60.69

GC content: 33.78

Gene sequence:

>897_bases
ATGGATTCTACTTTATTTTTACAACAACTTGTTAATGGACTTAGTTTAGGCAGTATGTATGCCCTTATTGCTGTTGGCTA
TACTATGGTTTATGGCGTGTTAAGACTTATTAATTTTGCTCACGGCGATATTATGATGGTTGGTGCTTATGCGGCTCTTT
TTTGCATGACTAATCTAAATGTTCCTTTTCTAGGAGCTTTGTCTTTAGCAATGATTTTTGCTGCTTGTGTTGGAATAGCT
ACAGATAGAATCGCTTATAAACCTTTAAGACAGGCTCCTAGAATTTCATTGTTGATTACAGCAATCGGTATTAGTTTTTT
CTTGCAAAATCTTTTTAATATGCTTTTTACTTCAACACCTAGAACTTTTACACCGCCAAGTTATTTTGAGGAAAGTGTTA
ATTTTGGTGGAGTGATAACAACTTATGGTTCTTTAATGGTTCCTGCTCTTACATTTGTTATTTTAATAGCAGTGTTATGG
ATTTTGTATAAAAGCAAATATGGTATAGCTATTCGTGCTTTGGCATTTGATATACAAACAGTAAATTTAATGGGTATAGA
TGCAAATCGTATTATTGCTATAGTTTTTGCCCTAGGTTCAGCTTTGGCAGCAGTTGGGGGTGTTTTTTGGGCTGCAAATT
ATTACTCTGTTGAACCTACTATGGGAACTTTAATAGGTTTAAAAGCTTTTGCTGCTGCAGTTTTAGGAGGTATAGGTTCT
GTAGTAGGTGCAGTTTTGGGTGGACTTATTATAGGATTTACTGAAGTTGTTGTTGTGGCTTTTTTTCCAGATTTATCAGG
CTTTAAAGATGCATTTGCTTTTATTTTTTTGGTGTTTATATTGTTATTTAGGCCTACGGGAATTTTAGGTATAAATTTTG
AAAAGAGTAGGTTTTAA

Upstream 100 bases:

>100_bases
AACAGGAAATGCAACTCGTTCTGTAGTGGTTAAAGAAATTAAAAATCAGAAGCAAAATTATAAAGATATTATCAATCCTT
AAAGGAAAAATAGAAAGATT

Downstream 100 bases:

>100_bases
TGATGGTTAGAATTAAGGTTTCACATTTAATCTTTTTAATTGCTTCAATTATTTTTATTTTCATTTCTCCTTATATTTTT
GGGGACTATGGATTAAACAT

Product: branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLNVPFLGALSLAMIFAACVGIA
TDRIAYKPLRQAPRISLLITAIGISFFLQNLFNMLFTSTPRTFTPPSYFEESVNFGGVITTYGSLMVPALTFVILIAVLW
ILYKSKYGIAIRALAFDIQTVNLMGIDANRIIAIVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF

Sequences:

>Translated_298_residues
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLNVPFLGALSLAMIFAACVGIA
TDRIAYKPLRQAPRISLLITAIGISFFLQNLFNMLFTSTPRTFTPPSYFEESVNFGGVITTYGSLMVPALTFVILIAVLW
ILYKSKYGIAIRALAFDIQTVNLMGIDANRIIAIVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF
>Mature_298_residues
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLNVPFLGALSLAMIFAACVGIA
TDRIAYKPLRQAPRISLLITAIGISFFLQNLFNMLFTSTPRTFTPPSYFEESVNFGGVITTYGSLMVPALTFVILIAVLW
ILYKSKYGIAIRALAFDIQTVNLMGIDANRIIAIVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=299, Percent_Identity=41.4715719063545, Blast_Score=194, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 32000; Mature: 32000

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VPFLGALSLAMIFAACVGIATDRIAYKPLRQAPRISLLITAIGISFFLQNLFNMLFTSTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
RTFTPPSYFEESVNFGGVITTYGSLMVPALTFVILIAVLWILYKSKYGIAIRALAFDIQT
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHEE
VNLMGIDANRIIAIVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHH
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHCCC
>Mature Secondary Structure
MDSTLFLQQLVNGLSLGSMYALIAVGYTMVYGVLRLINFAHGDIMMVGAYAALFCMTNLN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
VPFLGALSLAMIFAACVGIATDRIAYKPLRQAPRISLLITAIGISFFLQNLFNMLFTSTP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
RTFTPPSYFEESVNFGGVITTYGSLMVPALTFVILIAVLWILYKSKYGIAIRALAFDIQT
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHEE
VNLMGIDANRIIAIVFALGSALAAVGGVFWAANYYSVEPTMGTLIGLKAFAAAVLGGIGS
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHH
VVGAVLGGLIIGFTEVVVVAFFPDLSGFKDAFAFIFLVFILLFRPTGILGINFEKSRF
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]