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The map label for this gene is ruvA

Identifier: 57237644

GI number: 57237644

Start: 827771

End: 828322

Strand: Reverse

Name: ruvA

Synonym: CJE0890

Alternate gene names: 57237644

Gene position: 828322-827771 (Counterclockwise)

Preceding gene: 57237645

Following gene: 57237643

Centisome position: 46.59

GC content: 33.51

Gene sequence:

>552_bases
ATGGTTGTCGGCATCGAAGGAATAATCACAAAAAAAGAACCTACTTTTATCATTGTTAAATGTGCTAGTGGTTTAAGCTA
TGGGATATTTATTTCGCTTTTTTGTTCTGCTAAAATTCAAACTCAAGAAAAGCATGAGTTTTTTATTACTCAAATCATCA
AAGAAGATTCTAATAAATTTTATGGCTTCTTGGATAAAGATGAACAAAAAATGTTTGAAATGCTTTTAAAAGTCAATGGA
GTGGGTGCAAATACTGCTATGGCGGTATGCTCTAGTCTTGATGTAAATTCTTTTTACAAAGCGTTAAGTTTAGGCGATGA
AAGCGTGCTTAAAAAAGTACCTGGTATAGGTCCAAAAAGTGCGAAACGCATTATAGTAGAACTTTCAGATACAAAAACCA
AACTTGAAAATGTAAGCGATGATAAAAGTGAAGCCTTAGCCGCACTTCTTACTCTAGGCTTTAAACAAGAAAAAATCATA
AGTGTTTTAGCAAGTGCTCAAGCAACAGGCACAAGCGAACTCATCAAAGAAGCTCTTAAAAAACTAGGATAA

Upstream 100 bases:

>100_bases
ATGAAAGTGCTAAATTTATAGGTATTAAAAAAGTCATACAAAACAACCAAGAAAGTATAGAAATACATAAAAAATTAGAT
TATGAAGAAAAGGATATAGC

Downstream 100 bases:

>100_bases
AGGAATAAAATGAAATTTGCAATACTTTTTGGCGGAAATTCTTATGAACATGAGATCAGTATAGTAAGTGCTGTAGTACT
TAAAAAAGTTATTAATCAAA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MVVGIEGIITKKEPTFIIVKCASGLSYGIFISLFCSAKIQTQEKHEFFITQIIKEDSNKFYGFLDKDEQKMFEMLLKVNG
VGANTAMAVCSSLDVNSFYKALSLGDESVLKKVPGIGPKSAKRIIVELSDTKTKLENVSDDKSEALAALLTLGFKQEKII
SVLASAQATGTSELIKEALKKLG

Sequences:

>Translated_183_residues
MVVGIEGIITKKEPTFIIVKCASGLSYGIFISLFCSAKIQTQEKHEFFITQIIKEDSNKFYGFLDKDEQKMFEMLLKVNG
VGANTAMAVCSSLDVNSFYKALSLGDESVLKKVPGIGPKSAKRIIVELSDTKTKLENVSDDKSEALAALLTLGFKQEKII
SVLASAQATGTSELIKEALKKLG
>Mature_183_residues
MVVGIEGIITKKEPTFIIVKCASGLSYGIFISLFCSAKIQTQEKHEFFITQIIKEDSNKFYGFLDKDEQKMFEMLLKVNG
VGANTAMAVCSSLDVNSFYKALSLGDESVLKKVPGIGPKSAKRIIVELSDTKTKLENVSDDKSEALAALLTLGFKQEKII
SVLASAQATGTSELIKEALKKLG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=202, Percent_Identity=29.7029702970297, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_CAMJ8 (A8FLL2)

Other databases:

- EMBL:   CP000814
- RefSeq:   YP_001482326.1
- ProteinModelPortal:   A8FLL2
- SMR:   A8FLL2
- STRING:   A8FLL2
- GeneID:   5618413
- GenomeReviews:   CP000814_GR
- KEGG:   cju:C8J_0750
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   MRIYHES
- ProtClustDB:   PRK14601
- BioCyc:   CJEJ407148:C8J_0750-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 19906; Mature: 19906

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVGIEGIITKKEPTFIIVKCASGLSYGIFISLFCSAKIQTQEKHEFFITQIIKEDSNKF
CEECCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCE
YGFLDKDEQKMFEMLLKVNGVGANTAMAVCSSLDVNSFYKALSLGDESVLKKVPGIGPKS
EEECCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCCCCC
AKRIIVELSDTKTKLENVSDDKSEALAALLTLGFKQEKIISVLASAQATGTSELIKEALK
CCEEEEEECCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
KLG
HCC
>Mature Secondary Structure
MVVGIEGIITKKEPTFIIVKCASGLSYGIFISLFCSAKIQTQEKHEFFITQIIKEDSNKF
CEECCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCE
YGFLDKDEQKMFEMLLKVNGVGANTAMAVCSSLDVNSFYKALSLGDESVLKKVPGIGPKS
EEECCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCCCCC
AKRIIVELSDTKTKLENVSDDKSEALAALLTLGFKQEKIISVLASAQATGTSELIKEALK
CCEEEEEECCHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHH
KLG
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA