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The map label for this gene is rpoC [H]

Identifier: 57237533

GI number: 57237533

Start: 481278

End: 485831

Strand: Direct

Name: rpoC [H]

Synonym: CJE0529

Alternate gene names: 57237533

Gene position: 481278-485831 (Clockwise)

Preceding gene: 57237532

Following gene: 57237536

Centisome position: 27.07

GC content: 34.85

Gene sequence:

>4554_bases
ATGAGTAAATTTAAAGTAATAGAAATTAAAGAAGATGCAAGACCTAGAGATTTTGAAGCATTTCAACTAAGACTTGCAAG
TCCTGAAAAAATCAAATCATGGTCTTATGGAGAAGTAAAAAAACCAGAAACTATTAATTATAGAACCTTAAAGCCTGAAA
GAGATGGGCTTTTTTGTGCAAAGATTTTTGGACCTATAAGAGATTATGAGTGTCTTTGTGGTAAATACAAAAAAATGCGT
TTTAAAGGCGTTAAGTGTGAAAAATGTGGTGTTGAAGTAGCAAATTCAAAAGTGCGTCGTTCTAGAATGGGGCATATCGA
GCTTGTAACTCCTGTGGCTCATATTTGGTATGTTAATTCTCTTCCAAGCCGTATAGGAACGCTTTTGGGTGTTAAGATGA
AAGATCTTGAGCGCGTGCTTTATTATGAAGCTTATATTGTTGAAAACCCAGGTGATGCTTTCTATGATAATGAAAGTACT
AAAAAAGTGGAATATTGCGATGTTTTGAACGAAGAGCAATATCAAAATTTAATGCAACGCTATGAAAATAGCGGCTTTAA
AGCAAGAATGGGTGGAGAAGTTGTTCGTGATTTACTTGCAAATTTAGATCTTGTAGCGCTTTTAAATCAGCTTAAAGAAG
AAATGGGGGCTACAAATTCAGAGGCTAAGAAAAAAACTATCATTAAACGCTTAAAAGTTGTAGAAAATTTCTTAAATTCA
AATTTAAACGCCAATACCGATAGCGACGAAGCTGTACCAAATCGTCCTGAATGGATGATGATTACAAATCTTCCAGTTTT
ACCGCCAGATTTGCGTCCTTTAGTGGCTTTAGATGGTGGGAAATTTGCAGTTTCTGATGTGAATGACTTATATCGTCGTG
TTATCAATAGAAATACACGTCTTAAAAAACTTATGGAACTTGATGCACCTGAAATCATTATCAGAAATGAAAAAAGAATG
CTTCAAGAGGCTGTTGATGCGCTTTTTGACAACGGTCGTCGTGCTAATGCTGTAAAAGGAGCAAATAAACGCCCATTGAA
ATCTTTAAGTGAAATCATCAAAGGGAAACAAGGACGTTTTAGACAAAATCTACTAGGTAAAAGGGTGGATTTCTCAGGTC
GTAGCGTTATTGTTGTAGGTCCAAAACTTAGAATGGATCAATGCGGTTTACCTAAAAAAATGGCTTTAGAGCTTTTTAAG
CCACATCTTTTAGCTAAGCTTGAAGAAAAAGGTTATGCAACCACAGTAAAACAAGCTAAAAAAATGATAGAAAATAAAAC
CAATGAAGTTTGGGAATGTTTAGAAGAGGTAGTAAAGGGACATCCTGTTATGCTAAACCGTGCACCTACTTTGCATAAGC
TTTCTATCCAAGCTTTTCATCCTGTTTTAGTGGAAGGTAAGGCTATACAACTTCATCCTTTGGTTTGTGCAGCATTTAAC
GCAGACTTTGATGGGGATCAAATGGCAGTGCATGTACCGCTTTCTCAAGAGGCTATTGCAGAATGTAAAGTGCTTATGCT
TTCATCAATGAATATTCTTTTACCAGCAAGCGGTAAGTCTGTAACCGTTCCATCGCAAGATATGGTTTTAGGAATTTATT
ATCTTTCGTTGGAAAAAGCAGGTGCTAAAGGTTCGCATAAAATTTGTACAGGCATTGATGAAGTGATGATGGCACTTGAA
AGCAAGTGTTTGGATATTCATGCGAGCATACAAACTATGGTAGATGGTAGAAAGATTACCACTACAGCAGGAAGATTGAT
TATTAAATCCATCTTGCCTGATTTTGTGCCTGAAAATAGTTGGAATAAAGTCTTAAAGAAAAAAGACATTGCTGCACTTG
TAGATTATGTTTATAAACAAGGTGGTTTAGAGATTACAGCAAGTTTCTTAGATAGACTTAAAAATTTAGGTTTTGAATAT
GCAACTAAAGCAGGTATTTCAATTTCGATTGCAGATATTATTGTTCCTAATGATAAACAAAAAGCTATCGATGAAGCAAA
AAAACAAGTAAGAGAAATTCAAAATTCTTATAATCTCGGTTTGATTACTTCAGGGGAAAGATACAATAAAATCATTGATA
TTTGGAAAAGTACAAACAATGTTCTTTCAAAAGAAATGATGAAGCTTGTAGAAAAAGATAAAGAAGGTTTTAACTCTATT
TATATGATGGCAGATTCTGGTGCTAGGGGTAGTGCAGCTCAAATTTCTCAGCTTGCTGCGATGAGAGGACTTATGACCAA
ACCTGATGGTTCTATTATCGAAACGCCTATTATTTCAAATTTCCGTGAAGGGCTAAATGTTCTTGAATACTTTATTTCAA
CTCACGGTGCTAGAAAAGGTCTTGCAGATACCGCTCTTAAAACAGCAAATGCGGGTTATTTGACAAGAAAACTCATCGAT
GTTGCACAAAATGTAAAAATTACCATTGAAGATTGTGGAACACATGAGGGTGTTGAAATCAATGAAATTACCGCAGATAG
TTCTATTATAGAAACTTTAGAAGAAAGAATTTTAGGCAGGGTTTTAGCTGAGGATGTGATTGATCCTATTACAAATTCTG
TGCTTTTTGCAGAAGGTACTTTAATGGATGAGGAAAAAGCAAAAATTCTTGGCGAAAGCGGTATAAAAAGTGTCAATATC
CGCACTCCTATTACCTGCAAAGCTAAAAAAGGAATTTGTGCAAAATGTTATGGTATCAATCTTGGTGAAGGTAAATTAGT
AAAACCAGGCGAAGCAGTGGGAATTATTTCCGCTCAATCTATCGGTGAACCAGGAACGCAGCTAACTCTAAGAACTTTCC
ATAGCGGGGGAACTGCAAGTACGGATTTACAAGATAGACAAGTAAGCGCACAAAAAGAAGGTTTTATAAGATTTTATAAT
CTTAAAACTTATAAAAACAAAGAAGGTAAAAATATCGTAGCAAATCGTAGAAATGCGGCGGTTTTACTTGTGGAGCCAAA
AATCAAAACTCCATTTAAAGGTGTGATTAATATAGAAAATATTCATGAAGATGTGATTGTTTCTATTAAAGATAAAAAAC
AAGAAGTAAAATACATATTAAGAAAATACGATCTTGCTAAACCAAATGAATTAGCAGGTGTAAGTGGCAGTATAGATGGA
AAACTTTATTTGCCATATCAAAGCGGCATGCAAGTAGAAGAAAATGAAAGTATCGTAGAAGTGATTAAAGAGGGTTGGAA
TGTACCAAATCGTATTCCTTTTGCGAGTGAAATTTTAGTAGAAGATGGCGAGCCTGTAGTTCAAAATATCAAAGCAGGCG
AAAAAGGAACACTCAAATTTTACATCCTTAAAGGCGATGGTTTAGATAGAGTAAAAAATGTTAAAAAAGGTGATATTGTT
AAAGAAAAAGGATTCTTTGTAGTGATTGCTGATGAAAATGATAGAGAAGCAAAAAGACACTATATCCCAAGAGAATCTAA
GATAGAATTTAACGATAGTGAAAAAATCGATGACGCAAATACTATCATTGCAAGTGCTCCTAAAAAAGAAAGAAAAGTGA
TTGCAGAATGGGATGCTTATAATAATACTATCATTGCAGAAATTGATGGTGTTGTAAGCTTTGAGGATATTGAAGCAGGT
TATAGTGCTGATGAGCAAATTGATGAAGCTACAGGTAAGCGTTCTTTAGTAATTAATGAGTATTTACCTAGCGGAGTTAG
ACCAACTTTGGTAATTGCAGGAAAAGGTGATAAAGCTGTGCGTTATCACCTTGAACCAAAAACCGTTATTTTTGTTCATG
ATGGCGATAAAATTGCTCAAGCAGATATTTTAGCAAAAACTCCAAAAGCAGCAGCTAAATCAAAGGATATTACAGGAGGT
CTTCCAAGAGTTTCTGAGCTTTTTGAAGCAAGAAAACCAAAAAATGCGGCTGTGATTGCAGAAATTGATGGTGTTGTTCG
TTTTGATAAGCCTTTGCGTTCTAAAGAAAGAATTATTATCCAAGCAGAAGATGGAACAAGTGCTGAGTATTTAATCGACA
AATCAAAACATATTCAAGTAAGAGATGGAGAGTTTATTCATGCAGGTGAAAAACTTACAGATGGAGTTGTTTCGAGTCAT
GATGTGCTTAAAATTTTAGGTGAAAAAGCCTTGCATTATTATTTGATTTCTGAAATTCAGCAAGTTTATCGCGGACAAGG
TGTTGTGATTTCTGATAAACATATAGAAGTTATCGTTTCTCAAATGCTAAGACAAGTAAAAGTTGTAGATAGTGGACATA
CGAAATTTATTGAAGGTGATTTGGTTTCAAGACGTAAATTCCGTGAAGAAAATGAAAGAATCATTAGAATGGGTGGAGAA
CCAGCTATTGCCGAGCCTGTGCTTTTAGGTGTAACAAGAGCAGCGATTGGAAGTGATAGTGTGATTTCTGCGGCTTCATT
CCAAGAAACTACCAAAGTTTTAACTGAAGCAAGTATAGCAGGTAAATTTGACTACTTAGAAGATTTAAAAGAAAATGTTA
TTCTAGGTAGAATGATTCCTGTTGGAACAGGGCTTTATGGCGAACAAAATTTAAAACTTAAAGAACAAGAATAA

Upstream 100 bases:

>100_bases
AATGTTCCAGCAACAGGAATTCCTGAAACATTTTTTGTATTAACCAATGAGCTTAAATCTCTTGCTTTAGATGTTGAGAT
TTTTGATAAGGATGAAGATA

Downstream 100 bases:

>100_bases
AACTCTATTTTATAGCCCTTCGGGGCTATATTAATACAGTGTATCTAAATCATTAAAATAAATTTTTAAAACTTTTTCTA
TTTTATTTTTTTCTTCTAGA

Product: DNA-directed RNA polymerase, beta' subunit

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1517; Mature: 1516

Protein sequence:

>1517_residues
MSKFKVIEIKEDARPRDFEAFQLRLASPEKIKSWSYGEVKKPETINYRTLKPERDGLFCAKIFGPIRDYECLCGKYKKMR
FKGVKCEKCGVEVANSKVRRSRMGHIELVTPVAHIWYVNSLPSRIGTLLGVKMKDLERVLYYEAYIVENPGDAFYDNEST
KKVEYCDVLNEEQYQNLMQRYENSGFKARMGGEVVRDLLANLDLVALLNQLKEEMGATNSEAKKKTIIKRLKVVENFLNS
NLNANTDSDEAVPNRPEWMMITNLPVLPPDLRPLVALDGGKFAVSDVNDLYRRVINRNTRLKKLMELDAPEIIIRNEKRM
LQEAVDALFDNGRRANAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPKLRMDQCGLPKKMALELFK
PHLLAKLEEKGYATTVKQAKKMIENKTNEVWECLEEVVKGHPVMLNRAPTLHKLSIQAFHPVLVEGKAIQLHPLVCAAFN
ADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKSVTVPSQDMVLGIYYLSLEKAGAKGSHKICTGIDEVMMALE
SKCLDIHASIQTMVDGRKITTTAGRLIIKSILPDFVPENSWNKVLKKKDIAALVDYVYKQGGLEITASFLDRLKNLGFEY
ATKAGISISIADIIVPNDKQKAIDEAKKQVREIQNSYNLGLITSGERYNKIIDIWKSTNNVLSKEMMKLVEKDKEGFNSI
YMMADSGARGSAAQISQLAAMRGLMTKPDGSIIETPIISNFREGLNVLEYFISTHGARKGLADTALKTANAGYLTRKLID
VAQNVKITIEDCGTHEGVEINEITADSSIIETLEERILGRVLAEDVIDPITNSVLFAEGTLMDEEKAKILGESGIKSVNI
RTPITCKAKKGICAKCYGINLGEGKLVKPGEAVGIISAQSIGEPGTQLTLRTFHSGGTASTDLQDRQVSAQKEGFIRFYN
LKTYKNKEGKNIVANRRNAAVLLVEPKIKTPFKGVINIENIHEDVIVSIKDKKQEVKYILRKYDLAKPNELAGVSGSIDG
KLYLPYQSGMQVEENESIVEVIKEGWNVPNRIPFASEILVEDGEPVVQNIKAGEKGTLKFYILKGDGLDRVKNVKKGDIV
KEKGFFVVIADENDREAKRHYIPRESKIEFNDSEKIDDANTIIASAPKKERKVIAEWDAYNNTIIAEIDGVVSFEDIEAG
YSADEQIDEATGKRSLVINEYLPSGVRPTLVIAGKGDKAVRYHLEPKTVIFVHDGDKIAQADILAKTPKAAAKSKDITGG
LPRVSELFEARKPKNAAVIAEIDGVVRFDKPLRSKERIIIQAEDGTSAEYLIDKSKHIQVRDGEFIHAGEKLTDGVVSSH
DVLKILGEKALHYYLISEIQQVYRGQGVVISDKHIEVIVSQMLRQVKVVDSGHTKFIEGDLVSRRKFREENERIIRMGGE
PAIAEPVLLGVTRAAIGSDSVISAASFQETTKVLTEASIAGKFDYLEDLKENVILGRMIPVGTGLYGEQNLKLKEQE

Sequences:

>Translated_1517_residues
MSKFKVIEIKEDARPRDFEAFQLRLASPEKIKSWSYGEVKKPETINYRTLKPERDGLFCAKIFGPIRDYECLCGKYKKMR
FKGVKCEKCGVEVANSKVRRSRMGHIELVTPVAHIWYVNSLPSRIGTLLGVKMKDLERVLYYEAYIVENPGDAFYDNEST
KKVEYCDVLNEEQYQNLMQRYENSGFKARMGGEVVRDLLANLDLVALLNQLKEEMGATNSEAKKKTIIKRLKVVENFLNS
NLNANTDSDEAVPNRPEWMMITNLPVLPPDLRPLVALDGGKFAVSDVNDLYRRVINRNTRLKKLMELDAPEIIIRNEKRM
LQEAVDALFDNGRRANAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPKLRMDQCGLPKKMALELFK
PHLLAKLEEKGYATTVKQAKKMIENKTNEVWECLEEVVKGHPVMLNRAPTLHKLSIQAFHPVLVEGKAIQLHPLVCAAFN
ADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKSVTVPSQDMVLGIYYLSLEKAGAKGSHKICTGIDEVMMALE
SKCLDIHASIQTMVDGRKITTTAGRLIIKSILPDFVPENSWNKVLKKKDIAALVDYVYKQGGLEITASFLDRLKNLGFEY
ATKAGISISIADIIVPNDKQKAIDEAKKQVREIQNSYNLGLITSGERYNKIIDIWKSTNNVLSKEMMKLVEKDKEGFNSI
YMMADSGARGSAAQISQLAAMRGLMTKPDGSIIETPIISNFREGLNVLEYFISTHGARKGLADTALKTANAGYLTRKLID
VAQNVKITIEDCGTHEGVEINEITADSSIIETLEERILGRVLAEDVIDPITNSVLFAEGTLMDEEKAKILGESGIKSVNI
RTPITCKAKKGICAKCYGINLGEGKLVKPGEAVGIISAQSIGEPGTQLTLRTFHSGGTASTDLQDRQVSAQKEGFIRFYN
LKTYKNKEGKNIVANRRNAAVLLVEPKIKTPFKGVINIENIHEDVIVSIKDKKQEVKYILRKYDLAKPNELAGVSGSIDG
KLYLPYQSGMQVEENESIVEVIKEGWNVPNRIPFASEILVEDGEPVVQNIKAGEKGTLKFYILKGDGLDRVKNVKKGDIV
KEKGFFVVIADENDREAKRHYIPRESKIEFNDSEKIDDANTIIASAPKKERKVIAEWDAYNNTIIAEIDGVVSFEDIEAG
YSADEQIDEATGKRSLVINEYLPSGVRPTLVIAGKGDKAVRYHLEPKTVIFVHDGDKIAQADILAKTPKAAAKSKDITGG
LPRVSELFEARKPKNAAVIAEIDGVVRFDKPLRSKERIIIQAEDGTSAEYLIDKSKHIQVRDGEFIHAGEKLTDGVVSSH
DVLKILGEKALHYYLISEIQQVYRGQGVVISDKHIEVIVSQMLRQVKVVDSGHTKFIEGDLVSRRKFREENERIIRMGGE
PAIAEPVLLGVTRAAIGSDSVISAASFQETTKVLTEASIAGKFDYLEDLKENVILGRMIPVGTGLYGEQNLKLKEQE
>Mature_1516_residues
SKFKVIEIKEDARPRDFEAFQLRLASPEKIKSWSYGEVKKPETINYRTLKPERDGLFCAKIFGPIRDYECLCGKYKKMRF
KGVKCEKCGVEVANSKVRRSRMGHIELVTPVAHIWYVNSLPSRIGTLLGVKMKDLERVLYYEAYIVENPGDAFYDNESTK
KVEYCDVLNEEQYQNLMQRYENSGFKARMGGEVVRDLLANLDLVALLNQLKEEMGATNSEAKKKTIIKRLKVVENFLNSN
LNANTDSDEAVPNRPEWMMITNLPVLPPDLRPLVALDGGKFAVSDVNDLYRRVINRNTRLKKLMELDAPEIIIRNEKRML
QEAVDALFDNGRRANAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPKLRMDQCGLPKKMALELFKP
HLLAKLEEKGYATTVKQAKKMIENKTNEVWECLEEVVKGHPVMLNRAPTLHKLSIQAFHPVLVEGKAIQLHPLVCAAFNA
DFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKSVTVPSQDMVLGIYYLSLEKAGAKGSHKICTGIDEVMMALES
KCLDIHASIQTMVDGRKITTTAGRLIIKSILPDFVPENSWNKVLKKKDIAALVDYVYKQGGLEITASFLDRLKNLGFEYA
TKAGISISIADIIVPNDKQKAIDEAKKQVREIQNSYNLGLITSGERYNKIIDIWKSTNNVLSKEMMKLVEKDKEGFNSIY
MMADSGARGSAAQISQLAAMRGLMTKPDGSIIETPIISNFREGLNVLEYFISTHGARKGLADTALKTANAGYLTRKLIDV
AQNVKITIEDCGTHEGVEINEITADSSIIETLEERILGRVLAEDVIDPITNSVLFAEGTLMDEEKAKILGESGIKSVNIR
TPITCKAKKGICAKCYGINLGEGKLVKPGEAVGIISAQSIGEPGTQLTLRTFHSGGTASTDLQDRQVSAQKEGFIRFYNL
KTYKNKEGKNIVANRRNAAVLLVEPKIKTPFKGVINIENIHEDVIVSIKDKKQEVKYILRKYDLAKPNELAGVSGSIDGK
LYLPYQSGMQVEENESIVEVIKEGWNVPNRIPFASEILVEDGEPVVQNIKAGEKGTLKFYILKGDGLDRVKNVKKGDIVK
EKGFFVVIADENDREAKRHYIPRESKIEFNDSEKIDDANTIIASAPKKERKVIAEWDAYNNTIIAEIDGVVSFEDIEAGY
SADEQIDEATGKRSLVINEYLPSGVRPTLVIAGKGDKAVRYHLEPKTVIFVHDGDKIAQADILAKTPKAAAKSKDITGGL
PRVSELFEARKPKNAAVIAEIDGVVRFDKPLRSKERIIIQAEDGTSAEYLIDKSKHIQVRDGEFIHAGEKLTDGVVSSHD
VLKILGEKALHYYLISEIQQVYRGQGVVISDKHIEVIVSQMLRQVKVVDSGHTKFIEGDLVSRRKFREENERIIRMGGEP
AIAEPVLLGVTRAAIGSDSVISAASFQETTKVLTEASIAGKFDYLEDLKENVILGRMIPVGTGLYGEQNLKLKEQE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=649, Percent_Identity=27.2727272727273, Blast_Score=181, Evalue=3e-45,
Organism=Homo sapiens, GI39725938, Length=669, Percent_Identity=25.2615844544096, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI103471997, Length=617, Percent_Identity=24.9594813614263, Blast_Score=117, Evalue=9e-26,
Organism=Escherichia coli, GI2367335, Length=1017, Percent_Identity=54.0806293018682, Blast_Score=1138, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=583, Percent_Identity=25.557461406518, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25145495, Length=309, Percent_Identity=32.3624595469256, Blast_Score=138, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320061, Length=878, Percent_Identity=23.9179954441913, Blast_Score=195, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6324690, Length=332, Percent_Identity=29.8192771084337, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17530899, Length=717, Percent_Identity=26.0808926080893, Blast_Score=176, Evalue=9e-44,
Organism=Drosophila melanogaster, GI281360912, Length=852, Percent_Identity=23.5915492957746, Blast_Score=159, Evalue=2e-38,
Organism=Drosophila melanogaster, GI17647875, Length=348, Percent_Identity=26.7241379310345, Blast_Score=105, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 168839; Mature: 168708

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKFKVIEIKEDARPRDFEAFQLRLASPEKIKSWSYGEVKKPETINYRTLKPERDGLFCA
CCCEEEEEECCCCCCCCCCCCEEEECCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEE
KIFGPIRDYECLCGKYKKMRFKGVKCEKCGVEVANSKVRRSRMGHIELVTPVAHIWYVNS
HHHCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHH
LPSRIGTLLGVKMKDLERVLYYEAYIVENPGDAFYDNESTKKVEYCDVLNEEQYQNLMQR
HHHHHHHHHCCHHHHHHHHHHEEEEEEECCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHH
YENSGFKARMGGEVVRDLLANLDLVALLNQLKEEMGATNSEAKKKTIIKRLKVVENFLNS
HHCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
NLNANTDSDEAVPNRPEWMMITNLPVLPPDLRPLVALDGGKFAVSDVNDLYRRVINRNTR
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHCCCHH
LKKLMELDAPEIIIRNEKRMLQEAVDALFDNGRRANAVKGANKRPLKSLSEIIKGKQGRF
HHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
RQNLLGKRVDFSGRSVIVVGPKLRMDQCGLPKKMALELFKPHLLAKLEEKGYATTVKQAK
HHHHCCCCCCCCCCEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KMIENKTNEVWECLEEVVKGHPVMLNRAPTLHKLSIQAFHPVLVEGKAIQLHPLVCAAFN
HHHHCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHCCEEECCCEEEEECEEEEEEC
ADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKSVTVPSQDMVLGIYYLSLEKA
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCEEEEEEEEEECC
GAKGSHKICTGIDEVMMALESKCLDIHASIQTMVDGRKITTTAGRLIIKSILPDFVPENS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCC
WNKVLKKKDIAALVDYVYKQGGLEITASFLDRLKNLGFEYATKAGISISIADIIVPNDKQ
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCHHHHCCCCEEEEEEEEECCCHH
KAIDEAKKQVREIQNSYNLGLITSGERYNKIIDIWKSTNNVLSKEMMKLVEKDKEGFNSI
HHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
YMMADSGARGSAAQISQLAAMRGLMTKPDGSIIETPIISNFREGLNVLEYFISTHGARKG
EEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCC
LADTALKTANAGYLTRKLIDVAQNVKITIEDCGTHEGVEINEITADSSIIETLEERILGR
HHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHH
VLAEDVIDPITNSVLFAEGTLMDEEKAKILGESGIKSVNIRTPITCKAKKGICAKCYGIN
HHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCCCEEECCCCEEEECCCCCEEEEEECC
LGEGKLVKPGEAVGIISAQSIGEPGTQLTLRTFHSGGTASTDLQDRQVSAQKEGFIRFYN
CCCCCEECCCCEEEEEEHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEE
LKTYKNKEGKNIVANRRNAAVLLVEPKIKTPFKGVINIENIHEDVIVSIKDKKQEVKYIL
EEEECCCCCCEEEECCCCCEEEEECCCCCCCCCCEEECCCCCCEEEEEEHHHHHHHHHHH
RKYDLAKPNELAGVSGSIDGKLYLPYQSGMQVEENESIVEVIKEGWNVPNRIPFASEILV
HHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHEE
EDGEPVVQNIKAGEKGTLKFYILKGDGLDRVKNVKKGDIVKEKGFFVVIADENDREAKRH
CCCCHHHHHCCCCCCCCEEEEEEECCCHHHHHCCCCCCEEEECCEEEEEECCCCHHHHHH
YIPRESKIEFNDSEKIDDANTIIASAPKKERKVIAEWDAYNNTIIAEIDGVVSFEDIEAG
CCCCCCCCCCCCCCCCCCCCCEEECCCCHHCCEEEEECCCCCEEEEEECCEEEEHHHCCC
YSADEQIDEATGKRSLVINEYLPSGVRPTLVIAGKGDKAVRYHLEPKTVIFVHDGDKIAQ
CCCHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCEEEEEECCCCHHH
ADILAKTPKAAAKSKDITGGLPRVSELFEARKPKNAAVIAEIDGVVRFDKPLRSKERIII
HHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCEEEE
QAEDGTSAEYLIDKSKHIQVRDGEFIHAGEKLTDGVVSSHDVLKILGEKALHYYLISEIQ
EECCCCCHHEEECCCCEEEEECCCEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QVYRGQGVVISDKHIEVIVSQMLRQVKVVDSGHTKFIEGDLVSRRKFREENERIIRMGGE
HHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCCEEEECCC
PAIAEPVLLGVTRAAIGSDSVISAASFQETTKVLTEASIAGKFDYLEDLKENVILGRMIP
CCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEEEE
VGTGLYGEQNLKLKEQE
CCCCCCCCCCCCEECCC
>Mature Secondary Structure 
SKFKVIEIKEDARPRDFEAFQLRLASPEKIKSWSYGEVKKPETINYRTLKPERDGLFCA
CCEEEEEECCCCCCCCCCCCEEEECCHHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEE
KIFGPIRDYECLCGKYKKMRFKGVKCEKCGVEVANSKVRRSRMGHIELVTPVAHIWYVNS
HHHCCCCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHCCCEEEECHHHHHHHHHH
LPSRIGTLLGVKMKDLERVLYYEAYIVENPGDAFYDNESTKKVEYCDVLNEEQYQNLMQR
HHHHHHHHHCCHHHHHHHHHHEEEEEEECCCCCCCCCCCCCEEHHHHHCCHHHHHHHHHH
YENSGFKARMGGEVVRDLLANLDLVALLNQLKEEMGATNSEAKKKTIIKRLKVVENFLNS
HHCCCCEECCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCC
NLNANTDSDEAVPNRPEWMMITNLPVLPPDLRPLVALDGGKFAVSDVNDLYRRVINRNTR
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCEEEHHHHHHHHHHHCCCHH
LKKLMELDAPEIIIRNEKRMLQEAVDALFDNGRRANAVKGANKRPLKSLSEIIKGKQGRF
HHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
RQNLLGKRVDFSGRSVIVVGPKLRMDQCGLPKKMALELFKPHLLAKLEEKGYATTVKQAK
HHHHCCCCCCCCCCEEEEECCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KMIENKTNEVWECLEEVVKGHPVMLNRAPTLHKLSIQAFHPVLVEGKAIQLHPLVCAAFN
HHHHCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEHHHHCCEEECCCEEEEECEEEEEEC
ADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKSVTVPSQDMVLGIYYLSLEKA
CCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCEEECCCCCCEEEEEEEEEECC
GAKGSHKICTGIDEVMMALESKCLDIHASIQTMVDGRKITTTAGRLIIKSILPDFVPENS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCC
WNKVLKKKDIAALVDYVYKQGGLEITASFLDRLKNLGFEYATKAGISISIADIIVPNDKQ
HHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCHHHHCCCCEEEEEEEEECCCHH
KAIDEAKKQVREIQNSYNLGLITSGERYNKIIDIWKSTNNVLSKEMMKLVEKDKEGFNSI
HHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
YMMADSGARGSAAQISQLAAMRGLMTKPDGSIIETPIISNFREGLNVLEYFISTHGARKG
EEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCC
LADTALKTANAGYLTRKLIDVAQNVKITIEDCGTHEGVEINEITADSSIIETLEERILGR
HHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHH
VLAEDVIDPITNSVLFAEGTLMDEEKAKILGESGIKSVNIRTPITCKAKKGICAKCYGIN
HHHHHHHHHHHCCEEEECCCCCCHHHHHHHHCCCCCEEECCCCEEEECCCCCEEEEEECC
LGEGKLVKPGEAVGIISAQSIGEPGTQLTLRTFHSGGTASTDLQDRQVSAQKEGFIRFYN
CCCCCEECCCCEEEEEEHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEE
LKTYKNKEGKNIVANRRNAAVLLVEPKIKTPFKGVINIENIHEDVIVSIKDKKQEVKYIL
EEEECCCCCCEEEECCCCCEEEEECCCCCCCCCCEEECCCCCCEEEEEEHHHHHHHHHHH
RKYDLAKPNELAGVSGSIDGKLYLPYQSGMQVEENESIVEVIKEGWNVPNRIPFASEILV
HHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHEE
EDGEPVVQNIKAGEKGTLKFYILKGDGLDRVKNVKKGDIVKEKGFFVVIADENDREAKRH
CCCCHHHHHCCCCCCCCEEEEEEECCCHHHHHCCCCCCEEEECCEEEEEECCCCHHHHHH
YIPRESKIEFNDSEKIDDANTIIASAPKKERKVIAEWDAYNNTIIAEIDGVVSFEDIEAG
CCCCCCCCCCCCCCCCCCCCCEEECCCCHHCCEEEEECCCCCEEEEEECCEEEEHHHCCC
YSADEQIDEATGKRSLVINEYLPSGVRPTLVIAGKGDKAVRYHLEPKTVIFVHDGDKIAQ
CCCHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCEEEEEECCCCHHH
ADILAKTPKAAAKSKDITGGLPRVSELFEARKPKNAAVIAEIDGVVRFDKPLRSKERIII
HHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCCEEEE
QAEDGTSAEYLIDKSKHIQVRDGEFIHAGEKLTDGVVSSHDVLKILGEKALHYYLISEIQ
EECCCCCHHEEECCCCEEEEECCCEEECCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
QVYRGQGVVISDKHIEVIVSQMLRQVKVVDSGHTKFIEGDLVSRRKFREENERIIRMGGE
HHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCCEEEECCC
PAIAEPVLLGVTRAAIGSDSVISAASFQETTKVLTEASIAGKFDYLEDLKENVILGRMIP
CCCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEEEE
VGTGLYGEQNLKLKEQE
CCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA