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The map label for this gene is fur [H]

Identifier: 57237455

GI number: 57237455

Start: 402928

End: 403401

Strand: Direct

Name: fur [H]

Synonym: CJE0449

Alternate gene names: 57237455

Gene position: 402928-403401 (Clockwise)

Preceding gene: 57237454

Following gene: 57237456

Centisome position: 22.66

GC content: 30.59

Gene sequence:

>474_bases
ATGCTGATAGAAAATGTGGAATATGATGTTTTACTTGAGAGGTTTAAAAAAATATTAAGACAAGGCGGACTTAAATATAC
TAAGCAAAGAGAAGTGCTTTTAAAAACTCTTTATCACAGTGATACTCATTACACACCCGAAAGTTTATATATGGAAATCA
AACAAGCTGAACCTGATTTAAATGTAGGAATTGCAACTGTTTATCGTACTTTAAATTTACTTGAAGAAGCAGAAATGGTA
ACTTCCATTTCTTTTGGTTCAGCAGGTAAAAAATATGAGCTTGCTAATAAACCTCACCATGATCATATGATATGTAAAAA
TTGCGGAAAAATTATAGAGTTTGAAAATCCTATTATAGAAAGACAGCAAGCCTTGATTGCAAAAGAACATGGTTTTAAAC
TTACAGGGCATTTGATGCAGCTTTATGGTGTTTGTGGTGATTGTAATAATCAAAAAGTAAAGGTAAAAATATAA

Upstream 100 bases:

>100_bases
ATTATGAATCAACCTTTAACAGAAAATAGTCTAGATCATGCTAGTGAAAAGTTGCAAGATATTGTAAGTGATTTAAACAA
TACTCAAAAAGGGGAGTGAT

Downstream 100 bases:

>100_bases
ATGTTTGATAATATTTTAGAGCAGCAAAGAATAGAAAAAGCTAAAGAGTTAAAAAATTTAGGGATTAATCCTTATCCTCA
TTTTTTAGAAAAGGAAATGT

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MLIENVEYDVLLERFKKILRQGGLKYTKQREVLLKTLYHSDTHYTPESLYMEIKQAEPDLNVGIATVYRTLNLLEEAEMV
TSISFGSAGKKYELANKPHHDHMICKNCGKIIEFENPIIERQQALIAKEHGFKLTGHLMQLYGVCGDCNNQKVKVKI

Sequences:

>Translated_157_residues
MLIENVEYDVLLERFKKILRQGGLKYTKQREVLLKTLYHSDTHYTPESLYMEIKQAEPDLNVGIATVYRTLNLLEEAEMV
TSISFGSAGKKYELANKPHHDHMICKNCGKIIEFENPIIERQQALIAKEHGFKLTGHLMQLYGVCGDCNNQKVKVKI
>Mature_157_residues
MLIENVEYDVLLERFKKILRQGGLKYTKQREVLLKTLYHSDTHYTPESLYMEIKQAEPDLNVGIATVYRTLNLLEEAEMV
TSISFGSAGKKYELANKPHHDHMICKNCGKIIEFENPIIERQQALIAKEHGFKLTGHLMQLYGVCGDCNNQKVKVKI

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=133, Percent_Identity=42.1052631578947, Blast_Score=103, Evalue=7e-24,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18082; Mature: 18082

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIENVEYDVLLERFKKILRQGGLKYTKQREVLLKTLYHSDTHYTPESLYMEIKQAEPDL
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
NVGIATVYRTLNLLEEAEMVTSISFGSAGKKYELANKPHHDHMICKNCGKIIEFENPIIE
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHCCCCEECCCHHHH
RQQALIAKEHGFKLTGHLMQLYGVCGDCNNQKVKVKI
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEC
>Mature Secondary Structure
MLIENVEYDVLLERFKKILRQGGLKYTKQREVLLKTLYHSDTHYTPESLYMEIKQAEPDL
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
NVGIATVYRTLNLLEEAEMVTSISFGSAGKKYELANKPHHDHMICKNCGKIIEFENPIIE
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHCCCCEECCCHHHH
RQQALIAKEHGFKLTGHLMQLYGVCGDCNNQKVKVKI
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]