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The map label for this gene is fabZ

Identifier: 57237329

GI number: 57237329

Start: 286903

End: 287343

Strand: Direct

Name: fabZ

Synonym: CJE0322

Alternate gene names: 57237329

Gene position: 286903-287343 (Clockwise)

Preceding gene: 57237328

Following gene: 57237330

Centisome position: 16.14

GC content: 34.24

Gene sequence:

>441_bases
ATGATAGATGTAATGCAAATTCAAGAAATCTTACCACACCGTTATCCTTTTTTACTGGTAGATAAAATTACAGAATTAAA
AGTTAAAGAAGTGGTGCTAGGATATAAAAACATCAGTATAAGTGATCATGTTTTTATGGGACATTTTCCAGGGCATCCTA
TTTATCCTGGAGTTTTGATTTTAGAAGGTATGGCTCAAACAGGTGGAGTTTTAGCTTTTGAAAGTATGGAAGATAAAGTG
GATCCAAAAAGTAAAGTAGTTTATTTCACAGGCATAGATGGAGCAAAATTTAGAAATCCTGTGCGTCCTGGAGATAGGCT
TGATTATGAAATGAGCGTGGTTAAAAATCGTGGTAATATGTGGATTTTTAAAGGGCAAGCTTTTGTAGATGGAAATTTAG
TTGCAGAGGCCGAGCTTAAAGCTATGATAGTGGATAAATAA

Upstream 100 bases:

>100_bases
AATTTAAGAAATTTATTAAGAAAAACTTTTTTGTTAATATAATTTTTAATGATTTTTTTATATAATAAAATTTTTAATTG
TTTTCAAGGTTAATTTAATA

Downstream 100 bases:

>100_bases
TGAAAAAAATTCATCCAAGTGCGGTGATTGAAGAGGGTGCACAACTTGGTGACGATGTTGTAGTAGAAGCTTATGCTTAT
GTAAGCAAAGATGCTAAAAT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: trans-Delta2-enoyl-acyl-ACP; H2O [C]

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MIDVMQIQEILPHRYPFLLVDKITELKVKEVVLGYKNISISDHVFMGHFPGHPIYPGVLILEGMAQTGGVLAFESMEDKV
DPKSKVVYFTGIDGAKFRNPVRPGDRLDYEMSVVKNRGNMWIFKGQAFVDGNLVAEAELKAMIVDK

Sequences:

>Translated_146_residues
MIDVMQIQEILPHRYPFLLVDKITELKVKEVVLGYKNISISDHVFMGHFPGHPIYPGVLILEGMAQTGGVLAFESMEDKV
DPKSKVVYFTGIDGAKFRNPVRPGDRLDYEMSVVKNRGNMWIFKGQAFVDGNLVAEAELKAMIVDK
>Mature_146_residues
MIDVMQIQEILPHRYPFLLVDKITELKVKEVVLGYKNISISDHVFMGHFPGHPIYPGVLILEGMAQTGGVLAFESMEDKV
DPKSKVVYFTGIDGAKFRNPVRPGDRLDYEMSVVKNRGNMWIFKGQAFVDGNLVAEAELKAMIVDK

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=138, Percent_Identity=47.1014492753623, Blast_Score=136, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_CAMJ8 (A8FK62)

Other databases:

- EMBL:   CP000814
- RefSeq:   YP_001481826.1
- ProteinModelPortal:   A8FK62
- SMR:   A8FK62
- STRING:   A8FK62
- GeneID:   5618377
- GenomeReviews:   CP000814_GR
- KEGG:   cju:C8J_0250
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- ProtClustDB:   PRK00006
- BioCyc:   CJEJ407148:C8J_0250-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.- [C]

Molecular weight: Translated: 16441; Mature: 16441

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: ACT_SITE 48-48

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDVMQIQEILPHRYPFLLVDKITELKVKEVVLGYKNISISDHVFMGHFPGHPIYPGVLI
CCCHHHHHHHCCCCCCEEEECHHHHHEEEHHEECCCCCCCCCCEEECCCCCCCCCCCEEE
LEGMAQTGGVLAFESMEDKVDPKSKVVYFTGIDGAKFRNPVRPGDRLDYEMSVVKNRGNM
EECCCCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHCCCCCCCCCCCEEEEEEECCCCE
WIFKGQAFVDGNLVAEAELKAMIVDK
EEECCCEEECCCEEEECEEEEEEECC
>Mature Secondary Structure
MIDVMQIQEILPHRYPFLLVDKITELKVKEVVLGYKNISISDHVFMGHFPGHPIYPGVLI
CCCHHHHHHHCCCCCCEEEECHHHHHEEEHHEECCCCCCCCCCEEECCCCCCCCCCCEEE
LEGMAQTGGVLAFESMEDKVDPKSKVVYFTGIDGAKFRNPVRPGDRLDYEMSVVKNRGNM
EECCCCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHCCCCCCCCCCCEEEEEEECCCCE
WIFKGQAFVDGNLVAEAELKAMIVDK
EEECCCEEECCCEEEECEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-3-hydroxy-acyl-ACP [C]

Specific reaction: D-3-hydroxy-acyl-ACP = trans-Delta2-enoyl-acyl-ACP + H2O [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA