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The map label for this gene is infC

Identifier: 57237211

GI number: 57237211

Start: 202080

End: 202598

Strand: Direct

Name: infC

Synonym: CJE0200

Alternate gene names: 57237211

Gene position: 202080-202598 (Clockwise)

Preceding gene: 57237210

Following gene: 57237212

Centisome position: 11.37

GC content: 32.95

Gene sequence:

>519_bases
TTGAGTAAAGAAAAAGAAGTATTGCTCAATGAAGAAATAAGAGCGGATGAAATCAGATGTGTTGGCGATGATGGCAAAGT
TTATGGTATTATCAGTAGTGATGAAGCTTTAGAAATTGCAAATCGTTTAGGACTTGATCTTGTAATGATAGCTGCAGATG
CTAAGCCACCTGTTTGCAAGATCATGGACTATGGTAAATTCCGTTATCAACAAGAGAAAAAACAAAAAGAAGCAAAGAAA
AAACAAAAAGTGATTGATATAAAAGAAATCAAACTTTCTGTAAAAATTGCTCAAAATGATATTAATTACAAGGTAAAACA
TGCTTTAGAATTTTTAGAACAAGGTAAGCATGTGAGATTTCGTGTGTTCTTAAAAGGACGTGAAATGGCAACTCCTGAAG
CAGGTGTAGCTTTGCTTGAAAAAATTTGGACTATGATAGAAAATGAAGCTAATCGTGACAAAGAGCCAAATTTTGAAGGT
CGTTATGTAAATATGCTTGTAACTCCTAAAAAGGCTTAA

Upstream 100 bases:

>100_bases
GTAGCGTTGCTTTAAGAGATAGAAGAGCTAAAGAACAAAAAAATCTTAGCTTGGACGAATTTATTAAATTAGTTAAGGAG
AAAATGAGTGAGGTACACTT

Downstream 100 bases:

>100_bases
TCCACTTTTGTGGATAAGGCTTTTAAAGGTTTTAAATTTTGAAAGAAAATCCTTCTTTTTTAAAAGAGCAAATTATAACT
TATCTTGGAAATAAAAGAGC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSKEKEVLLNEEIRADEIRCVGDDGKVYGIISSDEALEIANRLGLDLVMIAADAKPPVCKIMDYGKFRYQQEKKQKEAKK
KQKVIDIKEIKLSVKIAQNDINYKVKHALEFLEQGKHVRFRVFLKGREMATPEAGVALLEKIWTMIENEANRDKEPNFEG
RYVNMLVTPKKA

Sequences:

>Translated_172_residues
MSKEKEVLLNEEIRADEIRCVGDDGKVYGIISSDEALEIANRLGLDLVMIAADAKPPVCKIMDYGKFRYQQEKKQKEAKK
KQKVIDIKEIKLSVKIAQNDINYKVKHALEFLEQGKHVRFRVFLKGREMATPEAGVALLEKIWTMIENEANRDKEPNFEG
RYVNMLVTPKKA
>Mature_171_residues
SKEKEVLLNEEIRADEIRCVGDDGKVYGIISSDEALEIANRLGLDLVMIAADAKPPVCKIMDYGKFRYQQEKKQKEAKKK
QKVIDIKEIKLSVKIAQNDINYKVKHALEFLEQGKHVRFRVFLKGREMATPEAGVALLEKIWTMIENEANRDKEPNFEGR
YVNMLVTPKKA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=43.2926829268293, Blast_Score=114, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_CAMJ8 (A8FK08)

Other databases:

- EMBL:   CP000814
- RefSeq:   YP_001481772.1
- ProteinModelPortal:   A8FK08
- STRING:   A8FK08
- GeneID:   5618102
- GenomeReviews:   CP000814_GR
- KEGG:   cju:C8J_0196
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   CJEJ407148:C8J_0196-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 19781; Mature: 19650

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEKEVLLNEEIRADEIRCVGDDGKVYGIISSDEALEIANRLGLDLVMIAADAKPPVCK
CCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHCCCEEEEEEECCCCCEEE
IMDYGKFRYQQEKKQKEAKKKQKVIDIKEIKLSVKIAQNDINYKVKHALEFLEQGKHVRF
EECCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCCCCHHHHHHHHHHCCCCEEE
RVFLKGREMATPEAGVALLEKIWTMIENEANRDKEPNFEGRYVNMLVTPKKA
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCC
>Mature Secondary Structure 
SKEKEVLLNEEIRADEIRCVGDDGKVYGIISSDEALEIANRLGLDLVMIAADAKPPVCK
CCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHCCCEEEEEEECCCCCEEE
IMDYGKFRYQQEKKQKEAKKKQKVIDIKEIKLSVKIAQNDINYKVKHALEFLEQGKHVRF
EECCCHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEECCCCCCHHHHHHHHHHCCCCEEE
RVFLKGREMATPEAGVALLEKIWTMIENEANRDKEPNFEGRYVNMLVTPKKA
EEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA