Click here to switch to the map view.

The map label for this gene is dcuA [H]

Identifier: 57237095

GI number: 57237095

Start: 96514

End: 97842

Strand: Direct

Name: dcuA [H]

Synonym: CJE0083

Alternate gene names: 57237095

Gene position: 96514-97842 (Clockwise)

Preceding gene: 57237094

Following gene: 57237096

Centisome position: 5.43

GC content: 37.4

Gene sequence:

>1329_bases
ATGATAATTTTGCAAGTAATCGTCCTTCTTGGGGCGATTTTTATCGGTATTCGCCTAGGCGGCATTGCTATAGGTTATGC
TGGAGGATTAGGTGTAGTTATACTAGGACTTGTTTTAGGTATGAAACCTGGTAATATTCCTTGGGATGTTATTTTAATTA
TTGCTGCAGCTATTGCAGCAATTTCTGCTATGCAACAAGCAGGTGGACTTGATTATATGGTAAGGGTGACAGAAAAAATT
TTAAGATCAAGCCCTAAATTTATAAATTATTTAGCTCCAGCTTGTGGATGGTTGCTTACAATCTTAGCAGGAACAGGAAA
TGCAGTATTTTCTTTAATGCCTGTTGTAGTTGATGTTGCAAAATCTCAAAACATAAAACCTAGTGTTCCACTTTCATTAA
TGGTTGTTTCTTCGCAAATTGGAATCACTGCTTCTCCTGTAAGTGCAGCTGTGGTTTATATGAGCGGAGTTTTAGAGCCA
CTTGGATGGAATTATCCAACTTTAATTGGAATTTGGATTAGCACAACTTTTGTAGCTTGTATGCTTGCAGCTTTTATAGT
GAGTTTAATCACTCCTATGGATTTGAGTAAGGATAGTGTTTATCAAGAACGATTAAAAGCAGGACTTGTAAAGGATGCAG
GAGCTGTTTTGCATGGCGAAGATAAACCAGGTGCTAAACTTTCAGTGGTAATTTTCTTGATCACTGTTTTGGCAGTTGTA
CTTTATGCAACCGCAATTTCAAGTAATATTAAATGGATTGATCCTGTTGTGGTTCCAAGAGATGCAGCTATTATGAGCTT
TTTACTTACTGCAGCAACTTTGATCACTTGGCTTTGTAAAGTTGAACCAGGTAAAATTCTTGACACTAGTGTATTTAAAA
GCGGTATGACTGCTTGTGTTTGTGTTTTTGGTGTAGCATGGCTTGGAAATACTTTTGTTGCAGGACACGAAGCTTCTATC
AAAGAAGTAGCAGGCGACTGGGTTAAACAAACCCCTGCTATGTTAGCAGTTGCATTTTTCTTTGCAAGTATGCTTTTATA
TTCCCAAGCAGCAACCGCAAAGGCCATTGTACCTGTAATTATCACTGCTTTAGGAATTTCAGCAGCAAATCCGCATGATT
CTTATATGCTTGTAGCTTGTTTTGCAGCAGTTTCAGCACTTTTTGTACTTCCAACTTATCCGACTTTGTTAGGTGCAGTG
CAAATGGATGATACAGGAACGACTAGAATTGGTAAATTTATATTTAATCACTCATTCTTTATACCAGGGGTTTTAGCTAT
TGCAATTGCTGTAGTATTAGGCTTTGTATTAGCTCCTATGCTTATTTAA

Upstream 100 bases:

>100_bases
TTAAGTAAAGAACAAATTGATGAAATTTTAACTCCATCAAATATGCTAAATCCTCACATGGAAGCTAAAAAATAGCATTT
TAGGATTTAATATGGATATA

Downstream 100 bases:

>100_bases
ATCAAACCCTAGGTTTTTCTCCTAGGGTTAAATTTTTTTCATTAGTTTTTAAGTATATACTACGTTATAATATTCATTTT
CAATTTTCTTTAAGAAAGGA

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVILGLVLGMKPGNIPWDVILIIAAAIAAISAMQQAGGLDYMVRVTEKI
LRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVAKSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEP
LGWNYPTLIGIWISTTFVACMLAAFIVSLITPMDLSKDSVYQERLKAGLVKDAGAVLHGEDKPGAKLSVVIFLITVLAVV
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACVCVFGVAWLGNTFVAGHEASI
KEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVIITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAV
QMDDTGTTRIGKFIFNHSFFIPGVLAIAIAVVLGFVLAPMLI

Sequences:

>Translated_442_residues
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVILGLVLGMKPGNIPWDVILIIAAAIAAISAMQQAGGLDYMVRVTEKI
LRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVAKSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEP
LGWNYPTLIGIWISTTFVACMLAAFIVSLITPMDLSKDSVYQERLKAGLVKDAGAVLHGEDKPGAKLSVVIFLITVLAVV
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACVCVFGVAWLGNTFVAGHEASI
KEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVIITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAV
QMDDTGTTRIGKFIFNHSFFIPGVLAIAIAVVLGFVLAPMLI
>Mature_442_residues
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVILGLVLGMKPGNIPWDVILIIAAAIAAISAMQQAGGLDYMVRVTEKI
LRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVAKSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEP
LGWNYPTLIGIWISTTFVACMLAAFIVSLITPMDLSKDSVYQERLKAGLVKDAGAVLHGEDKPGAKLSVVIFLITVLAVV
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACVCVFGVAWLGNTFVAGHEASI
KEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVIITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAV
QMDDTGTTRIGKFIFNHSFFIPGVLAIAIAVVLGFVLAPMLI

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790580, Length=442, Percent_Identity=53.393665158371, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1790565, Length=418, Percent_Identity=35.4066985645933, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 46388; Mature: 46388

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVILGLVLGMKPGNIPWDVILIIAAAIAA
CHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ISAMQQAGGLDYMVRVTEKILRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVA
HHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEPLGWNYPTLIGIWISTTFVAC
HCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MLAAFIVSLITPMDLSKDSVYQERLKAGLVKDAGAVLHGEDKPGAKLSVVIFLITVLAVV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHH
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACV
HHHHHHHCCCCEECCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CVFGVAWLGNTFVAGHEASIKEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVI
HHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAVQMDDTGTTRIGKFIFNHSFF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHHHHHCCCCH
IPGVLAIAIAVVLGFVLAPMLI
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIILQVIVLLGAIFIGIRLGGIAIGYAGGLGVVILGLVLGMKPGNIPWDVILIIAAAIAA
CHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ISAMQQAGGLDYMVRVTEKILRSSPKFINYLAPACGWLLTILAGTGNAVFSLMPVVVDVA
HHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
KSQNIKPSVPLSLMVVSSQIGITASPVSAAVVYMSGVLEPLGWNYPTLIGIWISTTFVAC
HCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
MLAAFIVSLITPMDLSKDSVYQERLKAGLVKDAGAVLHGEDKPGAKLSVVIFLITVLAVV
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHH
LYATAISSNIKWIDPVVVPRDAAIMSFLLTAATLITWLCKVEPGKILDTSVFKSGMTACV
HHHHHHHCCCCEECCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CVFGVAWLGNTFVAGHEASIKEVAGDWVKQTPAMLAVAFFFASMLLYSQAATAKAIVPVI
HHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITALGISAANPHDSYMLVACFAAVSALFVLPTYPTLLGAVQMDDTGTTRIGKFIFNHSFF
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHHHHHCCCCH
IPGVLAIAIAVVLGFVLAPMLI
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]