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The map label for this gene is flhF [H]

Identifier: 57237074

GI number: 57237074

Start: 76322

End: 77776

Strand: Reverse

Name: flhF [H]

Synonym: CJE0061

Alternate gene names: 57237074

Gene position: 77776-76322 (Counterclockwise)

Preceding gene: 57237075

Following gene: 57237073

Centisome position: 4.37

GC content: 30.52

Gene sequence:

>1455_bases
ATGGGACAACTTATACATACTTTTACTGTTGAAGATACAGAACAAATTATACCCAAAGTAAAAGAAGATTACGGAGATAA
AGCTTTAATTATAACAAATAAACAAATTCGTCCTAAAACCTTAAATCGCAGTGCGCTTTATGAGGTTATGGTAGCCATAG
AAGAAAGCGACTATGAAGAACACTTAAAAAAACAAGGAAAATCTTTACCTGCAAAAAAAAGCTCGCCAAAACCATCTTCT
ACCTCTCTTGCAGAAGAAAAAATTAGATCTCAAATCCCTCAAGAAGATGAAGATGTAGTCTTGGATTTCTCAAACACTCG
CTTAAATACAAATTTAAACACTGTCAAAAACAATGACTTAACTAAAAAAACCTATCAAGATTTTCCACAAAACAAAATCA
ACCCTCATCAAAATAAGACTCTAGGCTTTGATGATTTTAAAGAAAAACTAAGTGAAGTTAGCAATGAAATTTCTAAAGTC
ACAAACACACCTTTAGAAAATTACACCCCTAATCCAAATTATAATAAAAAAATAGAAAATTTTGAAAAGCAATTTGAAAA
ACAAATCAACAAGCTTAACGATAAAATAGATCTTCTTGCAGATATGATGTGGGACGATAAAGCTGAAGCTAGAAAAAATC
TTATTATACCTCCTGAATTTGCAAGTATTTATAAACAAGCCAAAGAAAGTGGAATGCTTGAAAATCATCTAGAAGCGATT
ATGAAAGCAACTATAGAAAATATGCCAGCTGCTATGAAAACCAACAAAGATGCGGTTCAAAGATATTTTCACTCACTTTT
AAGAAATATCTTGCCTTGTCGTGTTGAAAGCGATATAAAAAAACAAAAAATCATGATGCTAGTAGGCCCAACAGGAGTCG
GAAAAACAACAACCTTAGCTAAGTTAGCTTTTCGCTATGCTTATGGAGATAAGCGTTATAAAACAGGTATTATTACGCTT
GATACTTATAGAATCGGTGCGGTTGAGCAACTTTTTCAGTATGCAAAAATGATGAAACTTCCTATTATTGATAGCATAGA
ACCAAAGGATTTAGATGAAGCGATAAAAAGCTTAAATAATTGCGAAGTAATTTTAGTTGATACTATAGGAAATTCACAAT
ACGATCAAAGCAAACTTGCTAAAACTAAAGAATTTTTAATGCACTCAAATGCAGAAATTGATGTAAATTTAGTGGTTTCT
GCAAACACCAAACAGGAAGATTTAATGGAAATTTATAAAAATTTTTCATTCTTAAATATTGATACTTTGATTATTACTAA
ATTTGATGAAACAAAGGTTTTTGGAAATATCTTCTCTCTTGTTTATGAAACAAATATTCCTCTAAGCTTTTTCTCTATAG
GACAAGAAGTGCCAGATGATTTAGAAGTAGCCAATAGTGATTTTCTAGTTCATTGTATTTTAGAAGGGTTTAACAAAGGA
AAAAATAATGAATAA

Upstream 100 bases:

>100_bases
ACAAAAAGTCAAGCGTGATAAGTGGTGTGAGGTGCCTCATAAAGGGGCTAAAGAAAGAGTGAGTGTAATTTTGCCTTTAG
GCATGATATAAGGAATATAA

Downstream 100 bases:

>100_bases
CCAAGCAAATAAACTTCGCAATCTCATGAGTCAAAATGGAACCAAAAAATCCCAAAACACTCATTTTATAGCTATTACAA
GTGGAAAAGGTGGCGTTGGA

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MGQLIHTFTVEDTEQIIPKVKEDYGDKALIITNKQIRPKTLNRSALYEVMVAIEESDYEEHLKKQGKSLPAKKSSPKPSS
TSLAEEKIRSQIPQEDEDVVLDFSNTRLNTNLNTVKNNDLTKKTYQDFPQNKINPHQNKTLGFDDFKEKLSEVSNEISKV
TNTPLENYTPNPNYNKKIENFEKQFEKQINKLNDKIDLLADMMWDDKAEARKNLIIPPEFASIYKQAKESGMLENHLEAI
MKATIENMPAAMKTNKDAVQRYFHSLLRNILPCRVESDIKKQKIMMLVGPTGVGKTTTLAKLAFRYAYGDKRYKTGIITL
DTYRIGAVEQLFQYAKMMKLPIIDSIEPKDLDEAIKSLNNCEVILVDTIGNSQYDQSKLAKTKEFLMHSNAEIDVNLVVS
ANTKQEDLMEIYKNFSFLNIDTLIITKFDETKVFGNIFSLVYETNIPLSFFSIGQEVPDDLEVANSDFLVHCILEGFNKG
KNNE

Sequences:

>Translated_484_residues
MGQLIHTFTVEDTEQIIPKVKEDYGDKALIITNKQIRPKTLNRSALYEVMVAIEESDYEEHLKKQGKSLPAKKSSPKPSS
TSLAEEKIRSQIPQEDEDVVLDFSNTRLNTNLNTVKNNDLTKKTYQDFPQNKINPHQNKTLGFDDFKEKLSEVSNEISKV
TNTPLENYTPNPNYNKKIENFEKQFEKQINKLNDKIDLLADMMWDDKAEARKNLIIPPEFASIYKQAKESGMLENHLEAI
MKATIENMPAAMKTNKDAVQRYFHSLLRNILPCRVESDIKKQKIMMLVGPTGVGKTTTLAKLAFRYAYGDKRYKTGIITL
DTYRIGAVEQLFQYAKMMKLPIIDSIEPKDLDEAIKSLNNCEVILVDTIGNSQYDQSKLAKTKEFLMHSNAEIDVNLVVS
ANTKQEDLMEIYKNFSFLNIDTLIITKFDETKVFGNIFSLVYETNIPLSFFSIGQEVPDDLEVANSDFLVHCILEGFNKG
KNNE
>Mature_483_residues
GQLIHTFTVEDTEQIIPKVKEDYGDKALIITNKQIRPKTLNRSALYEVMVAIEESDYEEHLKKQGKSLPAKKSSPKPSST
SLAEEKIRSQIPQEDEDVVLDFSNTRLNTNLNTVKNNDLTKKTYQDFPQNKINPHQNKTLGFDDFKEKLSEVSNEISKVT
NTPLENYTPNPNYNKKIENFEKQFEKQINKLNDKIDLLADMMWDDKAEARKNLIIPPEFASIYKQAKESGMLENHLEAIM
KATIENMPAAMKTNKDAVQRYFHSLLRNILPCRVESDIKKQKIMMLVGPTGVGKTTTLAKLAFRYAYGDKRYKTGIITLD
TYRIGAVEQLFQYAKMMKLPIIDSIEPKDLDEAIKSLNNCEVILVDTIGNSQYDQSKLAKTKEFLMHSNAEIDVNLVVSA
NTKQEDLMEIYKNFSFLNIDTLIITKFDETKVFGNIFSLVYETNIPLSFFSIGQEVPDDLEVANSDFLVHCILEGFNKGK
NNE

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=230, Percent_Identity=30.8695652173913, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4507215, Length=230, Percent_Identity=30.8695652173913, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1789874, Length=209, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17539958, Length=202, Percent_Identity=32.1782178217822, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325345, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17647949, Length=191, Percent_Identity=32.9842931937173, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 55360; Mature: 55229

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQLIHTFTVEDTEQIIPKVKEDYGDKALIITNKQIRPKTLNRSALYEVMVAIEESDYEE
CCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHH
HLKKQGKSLPAKKSSPKPSSTSLAEEKIRSQIPQEDEDVVLDFSNTRLNTNLNTVKNNDL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCEECCCCCCCCCCCC
TKKTYQDFPQNKINPHQNKTLGFDDFKEKLSEVSNEISKVTNTPLENYTPNPNYNKKIEN
CHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
FEKQFEKQINKLNDKIDLLADMMWDDKAEARKNLIIPPEFASIYKQAKESGMLENHLEAI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHH
MKATIENMPAAMKTNKDAVQRYFHSLLRNILPCRVESDIKKQKIMMLVGPTGVGKTTTLA
HHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCEEEEEECCCCCCCHHHHH
KLAFRYAYGDKRYKTGIITLDTYRIGAVEQLFQYAKMMKLPIIDSIEPKDLDEAIKSLNN
HHHHHHHHCCCEEECEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
CEVILVDTIGNSQYDQSKLAKTKEFLMHSNAEIDVNLVVSANTKQEDLMEIYKNFSFLNI
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCEEEE
DTLIITKFDETKVFGNIFSLVYETNIPLSFFSIGQEVPDDLEVANSDFLVHCILEGFNKG
EEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHCCCCHHHHHHHHHHCCC
KNNE
CCCC
>Mature Secondary Structure 
GQLIHTFTVEDTEQIIPKVKEDYGDKALIITNKQIRPKTLNRSALYEVMVAIEESDYEE
CCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCHHH
HLKKQGKSLPAKKSSPKPSSTSLAEEKIRSQIPQEDEDVVLDFSNTRLNTNLNTVKNNDL
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCEECCCCCCCCCCCC
TKKTYQDFPQNKINPHQNKTLGFDDFKEKLSEVSNEISKVTNTPLENYTPNPNYNKKIEN
CHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
FEKQFEKQINKLNDKIDLLADMMWDDKAEARKNLIIPPEFASIYKQAKESGMLENHLEAI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHH
MKATIENMPAAMKTNKDAVQRYFHSLLRNILPCRVESDIKKQKIMMLVGPTGVGKTTTLA
HHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCEEEEEECCCCCCCHHHHH
KLAFRYAYGDKRYKTGIITLDTYRIGAVEQLFQYAKMMKLPIIDSIEPKDLDEAIKSLNN
HHHHHHHHCCCEEECEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCC
CEVILVDTIGNSQYDQSKLAKTKEFLMHSNAEIDVNLVVSANTKQEDLMEIYKNFSFLNI
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHCCCEEEE
DTLIITKFDETKVFGNIFSLVYETNIPLSFFSIGQEVPDDLEVANSDFLVHCILEGFNKG
EEEEEEECCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHCCCCHHHHHHHHHHCCC
KNNE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]