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The map label for this gene is dcuB [H]

Identifier: 57236980

GI number: 57236980

Start: 704384

End: 705808

Strand: Direct

Name: dcuB [H]

Synonym: CJE0772

Alternate gene names: 57236980

Gene position: 704384-705808 (Clockwise)

Preceding gene: 57236979

Following gene: 57236981

Centisome position: 39.62

GC content: 35.3

Gene sequence:

>1425_bases
ATGGACTTTTTAACAAGCCTTAGTGAGGGAGGGCAATTTGCAATCCAAATCATTATCGTTTTAATTTGTCTTTTTTACGG
TGCAAAAAAAGGCGGCATAGCGCTTGGTTTACTTGGTGGTATAGGTATTTTAATGCTTGTATTTACTTTTCATATAAAGC
CTGGAAAACCAGCCATAGATGTTATGCTTACAATTTTAGCGGTAGTGGTTGCGAGTGCAACTTTGCAAGCAAGCGGTGGT
TTGGATGTTATGCTTCAAATAGCAGAAAGAATTTTAAGACGCAATCCTAAATTTTTAACAATATTAGCGCCTTTTGTAAC
CTGCTTTTTGACTATACTTTGTGGAACAGGACATGTGGTTTATACTATTATGCCTATTATTTATGATATAGCGATTAAAA
ACGGTATTCGTCCTGAGCGTCCAATGGCGGCAGCTTCTATATCATCACAAATGGGTATTATTGCATCTCCTGTATCTGTG
GCTGTTGTGAGTTTGACTGCTTTGCTTTTAAATGCTAATCATAAATTAGCAGGTTTTGATGGCTATATCAATCTTCTTCA
AATTACTATACCTAGTACGCTTTTTGGTGTTTTATGTGTGGGAATTTTTTCTTGGTTTAGAGGAAAAGATTTGGATAAAG
ATGAAGTATTTCAAGAAAAACTTAAAGATCCTGAATTTAAAAAATATGTTTATGGGGATTCTAAAACACTTTTAGGTGTT
AAACTTCCAAAAAGCAATTGGGTTGCAATGTGGATTTTCTTAGGAGCTATTGCTTTAGTGGCTTTATTAGGTGTATTTGA
TTTCTTGCGTCCAAACTGGGGACAAGTTGTAAAAAATGGCATTCCTCAAGTAGACGCTTTAGGCAATCCTAAAATGGATG
TTTTATCCATGGTTTCAGTTATTCAGATGTTTATGCTTTTAGCAGGTTCTTTGATTATCATCTTTACTAAAACAGATGCA
AAGAAAATCGGCTCTAATGAAATTTTTAAATCAGGTATGATAGCTCTTGTTGCAGTTTTTGGAATTTCTTGGATGGCTGA
TACTATGTTTGCAGTTCACACTCCTATGATGAAAGCAGCGCTTGGAGATATAGTAAAAGAGCATCCTTGGACTTATGCTG
TAATGCTTCTTTTAATTTCAAAATTTGTAAATTCTCAAGCAGCGGCTATTTCGGCTTTTGTTCCTTTGGCTTTAGGAATT
GGTGTTGAACCTGGTGCAATTGTTGCCTTTGCGGCTGCTTGTTATGGATATTATATTTTACCAACTTATCCAAGCGATTT
GGCTACTATACAATTTGACAGATCAGGTACTACTCACATTGGTAAATTTGTTATCAATCATAGTTTTATTTTACCAGGTC
TTATAGGTGTAATCACTTCTTGTATAGCGGGATATTTTATCGCTATGGCAGCGGGTTATCTTTAA

Upstream 100 bases:

>100_bases
ATAAAAAATTATTGTTTTATTTTTAGAAATATTATTCTTTAATTTAAAAATGTGATACAATAATAACTGTTTTTAAATAT
TAATTTTCAAAGGAGTTAAA

Downstream 100 bases:

>100_bases
AAATTTTTAGTAGGATTTTTCCTGCTAAATTCTTCATTTGTCTTTTTATTTAATATAGATAAAAATTATAAATAAATCAT
AAAATTAGTATTAATCAAAA

Product: anaerobic C4-dicarboxylate transporter

Products: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MDFLTSLSEGGQFAIQIIIVLICLFYGAKKGGIALGLLGGIGILMLVFTFHIKPGKPAIDVMLTILAVVVASATLQASGG
LDVMLQIAERILRRNPKFLTILAPFVTCFLTILCGTGHVVYTIMPIIYDIAIKNGIRPERPMAAASISSQMGIIASPVSV
AVVSLTALLLNANHKLAGFDGYINLLQITIPSTLFGVLCVGIFSWFRGKDLDKDEVFQEKLKDPEFKKYVYGDSKTLLGV
KLPKSNWVAMWIFLGAIALVALLGVFDFLRPNWGQVVKNGIPQVDALGNPKMDVLSMVSVIQMFMLLAGSLIIIFTKTDA
KKIGSNEIFKSGMIALVAVFGISWMADTMFAVHTPMMKAALGDIVKEHPWTYAVMLLLISKFVNSQAAAISAFVPLALGI
GVEPGAIVAFAAACYGYYILPTYPSDLATIQFDRSGTTHIGKFVINHSFILPGLIGVITSCIAGYFIAMAAGYL

Sequences:

>Translated_474_residues
MDFLTSLSEGGQFAIQIIIVLICLFYGAKKGGIALGLLGGIGILMLVFTFHIKPGKPAIDVMLTILAVVVASATLQASGG
LDVMLQIAERILRRNPKFLTILAPFVTCFLTILCGTGHVVYTIMPIIYDIAIKNGIRPERPMAAASISSQMGIIASPVSV
AVVSLTALLLNANHKLAGFDGYINLLQITIPSTLFGVLCVGIFSWFRGKDLDKDEVFQEKLKDPEFKKYVYGDSKTLLGV
KLPKSNWVAMWIFLGAIALVALLGVFDFLRPNWGQVVKNGIPQVDALGNPKMDVLSMVSVIQMFMLLAGSLIIIFTKTDA
KKIGSNEIFKSGMIALVAVFGISWMADTMFAVHTPMMKAALGDIVKEHPWTYAVMLLLISKFVNSQAAAISAFVPLALGI
GVEPGAIVAFAAACYGYYILPTYPSDLATIQFDRSGTTHIGKFVINHSFILPGLIGVITSCIAGYFIAMAAGYL
>Mature_474_residues
MDFLTSLSEGGQFAIQIIIVLICLFYGAKKGGIALGLLGGIGILMLVFTFHIKPGKPAIDVMLTILAVVVASATLQASGG
LDVMLQIAERILRRNPKFLTILAPFVTCFLTILCGTGHVVYTIMPIIYDIAIKNGIRPERPMAAASISSQMGIIASPVSV
AVVSLTALLLNANHKLAGFDGYINLLQITIPSTLFGVLCVGIFSWFRGKDLDKDEVFQEKLKDPEFKKYVYGDSKTLLGV
KLPKSNWVAMWIFLGAIALVALLGVFDFLRPNWGQVVKNGIPQVDALGNPKMDVLSMVSVIQMFMLLAGSLIIIFTKTDA
KKIGSNEIFKSGMIALVAVFGISWMADTMFAVHTPMMKAALGDIVKEHPWTYAVMLLLISKFVNSQAAAISAFVPLALGI
GVEPGAIVAFAAACYGYYILPTYPSDLATIQFDRSGTTHIGKFVINHSFILPGLIGVITSCIAGYFIAMAAGYL

Specific function: Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane [H]

COG id: COG2704

COG function: function code R; Anaerobic C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuA/dcuB transporter (TC 2.A.13.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790565, Length=454, Percent_Identity=68.942731277533, Blast_Score=566, Evalue=1e-162,
Organism=Escherichia coli, GI1790580, Length=452, Percent_Identity=34.9557522123894, Blast_Score=263, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004668 [H]

Pfam domain/function: PF03605 DcuA_DcuB [H]

EC number: NA

Molecular weight: Translated: 50988; Mature: 50988

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFLTSLSEGGQFAIQIIIVLICLFYGAKKGGIALGLLGGIGILMLVFTFHIKPGKPAID
CCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHH
VMLTILAVVVASATLQASGGLDVMLQIAERILRRNPKFLTILAPFVTCFLTILCGTGHVV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHH
YTIMPIIYDIAIKNGIRPERPMAAASISSQMGIIASPVSVAVVSLTALLLNANHKLAGFD
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GYINLLQITIPSTLFGVLCVGIFSWFRGKDLDKDEVFQEKLKDPEFKKYVYGDSKTLLGV
HHEEHHEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHEECCCCEEEEE
KLPKSNWVAMWIFLGAIALVALLGVFDFLRPNWGQVVKNGIPQVDALGNPKMDVLSMVSV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHH
IQMFMLLAGSLIIIFTKTDAKKIGSNEIFKSGMIALVAVFGISWMADTMFAVHTPMMKAA
HHHHHHHHCCEEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDIVKEHPWTYAVMLLLISKFVNSQAAAISAFVPLALGIGVEPGAIVAFAAACYGYYIL
HHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEE
PTYPSDLATIQFDRSGTTHIGKFVINHSFILPGLIGVITSCIAGYFIAMAAGYL
CCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFLTSLSEGGQFAIQIIIVLICLFYGAKKGGIALGLLGGIGILMLVFTFHIKPGKPAID
CCCHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHH
VMLTILAVVVASATLQASGGLDVMLQIAERILRRNPKFLTILAPFVTCFLTILCGTGHVV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCHHH
YTIMPIIYDIAIKNGIRPERPMAAASISSQMGIIASPVSVAVVSLTALLLNANHKLAGFD
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GYINLLQITIPSTLFGVLCVGIFSWFRGKDLDKDEVFQEKLKDPEFKKYVYGDSKTLLGV
HHEEHHEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHEECCCCEEEEE
KLPKSNWVAMWIFLGAIALVALLGVFDFLRPNWGQVVKNGIPQVDALGNPKMDVLSMVSV
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCCCHHHHHHHHH
IQMFMLLAGSLIIIFTKTDAKKIGSNEIFKSGMIALVAVFGISWMADTMFAVHTPMMKAA
HHHHHHHHCCEEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGDIVKEHPWTYAVMLLLISKFVNSQAAAISAFVPLALGIGVEPGAIVAFAAACYGYYIL
HHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCEEEE
PTYPSDLATIQFDRSGTTHIGKFVINHSFILPGLIGVITSCIAGYFIAMAAGYL
CCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: C4-dicarboxylates [Periplasm]; C4-dicarboxylates [Periplasm] [C]

Specific reaction: C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] = C4-dicarboxylates [Periplasm] + C4-dicarboxylates [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]