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The map label for this gene is queF [H]

Identifier: 57236909

GI number: 57236909

Start: 1770705

End: 1771088

Strand: Reverse

Name: queF [H]

Synonym: CJE1892

Alternate gene names: 57236909

Gene position: 1771088-1770705 (Counterclockwise)

Preceding gene: 57236911

Following gene: 57236908

Centisome position: 99.62

GC content: 31.51

Gene sequence:

>384_bases
ATGCGTTATGGTGAAAAAGAAATCAAAGAATTTGATGTAGAAAATATGGAAATTTGGCCAAATGATGCGAAAAATGACTA
TATCATTAAAATCACTTTGCCTGAATTTATGTGTTGTTGTCCGCGTTCGGGCTATCCTGACTTTGCAACGATTTATCTTG
AGTATATGCCTAATAAATTTGTGGTTGAGCTTAAGGCTATAAAACTTTATATCAATACTTTTATGTATAGAAATGTTTCA
CATGAAGCAAGTATCAATGAAATTTATAATACTTTAAAAGATAAATTAAAACCAAAATGGATTAAAGTTGTTGGGGATTT
TAACCCGCGTGGAAATGTACATACGGTGATAGAATGTCGTAGCGATATGGTAGTGCCAAAATAA

Upstream 100 bases:

>100_bases
TTTGTCTTTTTTATGCAATTTGCTAAAAATGTTTATTTTTCAATTGCTCTAAAAGTAATTTTTTATATAATTTTCTAAAA
ATTTTCAATAAGGAAAGCTC

Downstream 100 bases:

>100_bases
TATTTGAGTAAAATATTAACATATTTTTATGTAAAGATTAAGTATTTTATAAAAAATTCTTATTTAATCTTTGAAGAATA
TATAATATAAAAAGATCTAA

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MRYGEKEIKEFDVENMEIWPNDAKNDYIIKITLPEFMCCCPRSGYPDFATIYLEYMPNKFVVELKAIKLYINTFMYRNVS
HEASINEIYNTLKDKLKPKWIKVVGDFNPRGNVHTVIECRSDMVVPK

Sequences:

>Translated_127_residues
MRYGEKEIKEFDVENMEIWPNDAKNDYIIKITLPEFMCCCPRSGYPDFATIYLEYMPNKFVVELKAIKLYINTFMYRNVS
HEASINEIYNTLKDKLKPKWIKVVGDFNPRGNVHTVIECRSDMVVPK
>Mature_127_residues
MRYGEKEIKEFDVENMEIWPNDAKNDYIIKITLPEFMCCCPRSGYPDFATIYLEYMPNKFVVELKAIKLYINTFMYRNVS
HEASINEIYNTLKDKLKPKWIKVVGDFNPRGNVHTVIECRSDMVVPK

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) [H]

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016856
- InterPro:   IPR020602 [H]

Pfam domain/function: PF01227 GTP_cyclohydroI [H]

EC number: =1.7.1.13 [H]

Molecular weight: Translated: 15039; Mature: 15039

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYGEKEIKEFDVENMEIWPNDAKNDYIIKITLPEFMCCCPRSGYPDFATIYLEYMPNKF
CCCCHHHHHHCCCCCEEECCCCCCCCEEEEEECCHHHHCCCCCCCCCCEEEEEEECCCEE
VVELKAIKLYINTFMYRNVSHEASINEIYNTLKDKLKPKWIKVVGDFNPRGNVHTVIECR
EEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEC
SDMVVPK
CCCCCCC
>Mature Secondary Structure
MRYGEKEIKEFDVENMEIWPNDAKNDYIIKITLPEFMCCCPRSGYPDFATIYLEYMPNKF
CCCCHHHHHHCCCCCEEECCCCCCCCEEEEEECCHHHHCCCCCCCCCCEEEEEEECCCEE
VVELKAIKLYINTFMYRNVSHEASINEIYNTLKDKLKPKWIKVVGDFNPRGNVHTVIECR
EEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEEEEC
SDMVVPK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA