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The map label for this gene is coaD

Identifier: 57235054

GI number: 57235054

Start: 184562

End: 185041

Strand: Direct

Name: coaD

Synonym: DET0190

Alternate gene names: 57235054

Gene position: 184562-185041 (Clockwise)

Preceding gene: 57235055

Following gene: 57235053

Centisome position: 12.56

GC content: 50.0

Gene sequence:

>480_bases
TTGATAGCCATTTACCCGGGCCGGTTTGACCCGGTAACCCTAGGCCATCTCAGCGTCGCCAGACGCGCTTCTGGCTTTTG
TGACCGGCTGATTATTGCTGTCTTTGATAATCCTGCCAAACCGGGTCTTTTTACGGCTGCCGAAAGGGTAGACCTTATTA
AGCAATCCGTCAAAGACCTTCCTAATGTAGAGGTGCATTCTTTCAGCGGGCTTATGGTTAATTTTGCCCGCAGGATGGGT
GTTTCACTTATAATCCGCGGCCTCAGGGTAGGGGCTGATTTTGAGCGTGAAATGGAAATGTACGTCATGAACCGCCGTCT
GGACGAGGGGATTGAGCTTTGCTGTCTTTTCTCAGAGCCTCAGTATCAGTATCTCAGTGCTTCGCTTATCAAAGAAGTGG
TGATGCTGGGGGGGGATTCAAGCGGGTTAATCTCGGAACATGTGGCAGATGCTTTAAAAAACAAGTTGGCGTCTGCCTAG

Upstream 100 bases:

>100_bases
GCCCATCTGACCCTGGCGGAGCGTTACGGGCGGCTTACGATGTTAAAAGAACATCGTCACGGTGATAGCCTGATTGCTAT
ATATAGAAAGGACAGCCGTT

Downstream 100 bases:

>100_bases
TGTGGTATAATCAATTAATTATTTTACAGGAGGGTGTATCGCCAGAAGAAGTTTTGCTTAAGACAGATTTTGGAGGTAGA
AGGAATTTATGTCGTTCAAG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MIAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDLIKQSVKDLPNVEVHSFSGLMVNFARRMG
VSLIIRGLRVGADFEREMEMYVMNRRLDEGIELCCLFSEPQYQYLSASLIKEVVMLGGDSSGLISEHVADALKNKLASA

Sequences:

>Translated_159_residues
MIAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDLIKQSVKDLPNVEVHSFSGLMVNFARRMG
VSLIIRGLRVGADFEREMEMYVMNRRLDEGIELCCLFSEPQYQYLSASLIKEVVMLGGDSSGLISEHVADALKNKLASA
>Mature_159_residues
MIAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDLIKQSVKDLPNVEVHSFSGLMVNFARRMG
VSLIIRGLRVGADFEREMEMYVMNRRLDEGIELCCLFSEPQYQYLSASLIKEVVMLGGDSSGLISEHVADALKNKLASA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=45.1612903225806, Blast_Score=138, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_DEHE1 (Q3ZA11)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_180938.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q3ZA11
- SMR:   Q3ZA11
- STRING:   Q3ZA11
- GeneID:   3230524
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET0190
- NMPDR:   fig|243164.3.peg.195
- TIGR:   DET0190
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q3ZA11
- ProtClustDB:   PRK00168
- BioCyc:   DETH243164:DET_0190-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17566; Mature: 17566

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDLIKQSVKDL
CEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHC
PNVEVHSFSGLMVNFARRMGVSLIIRGLRVGADFEREMEMYVMNRRLDEGIELCCLFSEP
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCC
QYQYLSASLIKEVVMLGGDSSGLISEHVADALKNKLASA
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIAIYPGRFDPVTLGHLSVARRASGFCDRLIIAVFDNPAKPGLFTAAERVDLIKQSVKDL
CEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHC
PNVEVHSFSGLMVNFARRMGVSLIIRGLRVGADFEREMEMYVMNRRLDEGIELCCLFSEP
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCC
QYQYLSASLIKEVVMLGGDSSGLISEHVADALKNKLASA
CHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA