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The map label for this gene is ydjJ [C]

Identifier: 57235047

GI number: 57235047

Start: 122839

End: 123864

Strand: Direct

Name: ydjJ [C]

Synonym: DET0125

Alternate gene names: 57235047

Gene position: 122839-123864 (Clockwise)

Preceding gene: 57235050

Following gene: 57235046

Centisome position: 8.36

GC content: 55.75

Gene sequence:

>1026_bases
ATGAAAGCGGTCTTGCTGGAAGAACCGGCTAAACTTAGCCTGGCGGAGGTGGACACTCCGTCCTGCCCCAAGGGTGGTGT
GCTCTTGGAGGTAGCCTGCTGTGCAATCTGCGGCACAGACGTAAAGATGTTCCGGCGGGGACACCGTGACCTTAAGTATC
CCCGGATACTGGGGCATGAAATAGCCGCTGTGGTAGCCTGCTCTGAACACCCTGATTTCAAGGCGGGTGACAGGGTGCAG
GTTTATCCGGGTATTGCCTGCGGGGTCTGCCCGCTTTGCCTGCAGGGCAGGGAGAATTTGTGCGGGCAGGTGAAAATAAT
CGGTTTTAATTATGACGGGGGCTTGGCCGAATATATGGCACTTCCCCCTGAAAGCCTGCCTGGCGGGCTTAACATAATAC
CTGAGAATGTTTCAGACGAAGAAGCCTCTCTGGCTGAGCCGCTTGCCAGCTGTATCCACAGCCAGTCTGTTAGCCGGGTG
GGGGACGGAGACCGGGTGCTGGTGCTGGGGGCTGGGCCTTTAGGTCTTTTACAGGCCATGCTCGCCCGGCATAACGGGGC
GGAAAAGGTGCTTATGGCCGAAGTCCTGCCTGACAGGGTGTGTGGGGCGGAACTGGCCTGCCCTGACGGGGTGATAGATT
TGGCAAAGACCAGCCTCAGGCAGGGGGTTTTTGAGCAGACCGGGGGGGCGGGGGTAGATGTGATTTTGATTGCCAGTTCG
GGGGTAGAAGTGGGAGAGCTGCCCTCTGTTTTGAGCCCCGGCGGGCGGATAAATTTCTTTTCCGGTCTGCCTAAAGACCG
TTCTGAATTCAGCCTGGACGCCAACACTATCCATTACCGGGAGCTGGCCTTGAGCGGCTCTTACGGCTCTACTCCAGCGG
ATAATACCCGGGCGCTTAGCCTGATAACGGATGGGATTATACCTGTAAAAAGGCTTATCAGCCGGGTAACGGGTATTTCA
GATATAGAGGAGGCTTTTCTGGGGGTGGAAAAGCTAAAAGGCCTTAAAACCATTATCAAATTTTAA

Upstream 100 bases:

>100_bases
GTGGGAAATGGTAAATCCCTGAGCCGAAAGGTTTGGGGTTTTATTTTTTTTAATCCTCAAACCTTGGTGGTTTGGGGATT
TTTTTATTATGGGGGGAAAT

Downstream 100 bases:

>100_bases
TAAAAAAGAGGGAAACAAAAGTGGACGAAAACAGGGTAAAAAATTTCGGGGCTGTCATAAGCCGCCTTATTTCAAAGGAA
AATCTTAACCGTGAAGAAGT

Product: alcohol dehydrogenase, zinc-containing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKAVLLEEPAKLSLAEVDTPSCPKGGVLLEVACCAICGTDVKMFRRGHRDLKYPRILGHEIAAVVACSEHPDFKAGDRVQ
VYPGIACGVCPLCLQGRENLCGQVKIIGFNYDGGLAEYMALPPESLPGGLNIIPENVSDEEASLAEPLASCIHSQSVSRV
GDGDRVLVLGAGPLGLLQAMLARHNGAEKVLMAEVLPDRVCGAELACPDGVIDLAKTSLRQGVFEQTGGAGVDVILIASS
GVEVGELPSVLSPGGRINFFSGLPKDRSEFSLDANTIHYRELALSGSYGSTPADNTRALSLITDGIIPVKRLISRVTGIS
DIEEAFLGVEKLKGLKTIIKF

Sequences:

>Translated_341_residues
MKAVLLEEPAKLSLAEVDTPSCPKGGVLLEVACCAICGTDVKMFRRGHRDLKYPRILGHEIAAVVACSEHPDFKAGDRVQ
VYPGIACGVCPLCLQGRENLCGQVKIIGFNYDGGLAEYMALPPESLPGGLNIIPENVSDEEASLAEPLASCIHSQSVSRV
GDGDRVLVLGAGPLGLLQAMLARHNGAEKVLMAEVLPDRVCGAELACPDGVIDLAKTSLRQGVFEQTGGAGVDVILIASS
GVEVGELPSVLSPGGRINFFSGLPKDRSEFSLDANTIHYRELALSGSYGSTPADNTRALSLITDGIIPVKRLISRVTGIS
DIEEAFLGVEKLKGLKTIIKF
>Mature_341_residues
MKAVLLEEPAKLSLAEVDTPSCPKGGVLLEVACCAICGTDVKMFRRGHRDLKYPRILGHEIAAVVACSEHPDFKAGDRVQ
VYPGIACGVCPLCLQGRENLCGQVKIIGFNYDGGLAEYMALPPESLPGGLNIIPENVSDEEASLAEPLASCIHSQSVSRV
GDGDRVLVLGAGPLGLLQAMLARHNGAEKVLMAEVLPDRVCGAELACPDGVIDLAKTSLRQGVFEQTGGAGVDVILIASS
GVEVGELPSVLSPGGRINFFSGLPKDRSEFSLDANTIHYRELALSGSYGSTPADNTRALSLITDGIIPVKRLISRVTGIS
DIEEAFLGVEKLKGLKTIIKF

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=349, Percent_Identity=27.7936962750716, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1788073, Length=347, Percent_Identity=29.6829971181556, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI226510992, Length=332, Percent_Identity=27.710843373494, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787863, Length=272, Percent_Identity=31.25, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1790045, Length=357, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788075, Length=343, Percent_Identity=27.4052478134111, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082125, Length=362, Percent_Identity=29.5580110497238, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790718, Length=343, Percent_Identity=26.2390670553936, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788407, Length=306, Percent_Identity=24.5098039215686, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786825, Length=266, Percent_Identity=27.8195488721804, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87081918, Length=357, Percent_Identity=28.8515406162465, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=338, Percent_Identity=28.4023668639053, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562878, Length=194, Percent_Identity=33.5051546391753, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323099, Length=355, Percent_Identity=28.169014084507, Blast_Score=116, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6322619, Length=337, Percent_Identity=28.7833827893175, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319955, Length=338, Percent_Identity=28.9940828402367, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319258, Length=204, Percent_Identity=27.4509803921569, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319257, Length=338, Percent_Identity=25.4437869822485, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17737897, Length=334, Percent_Identity=30.2395209580838, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI17137530, Length=323, Percent_Identity=30.030959752322, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221457811, Length=192, Percent_Identity=27.6041666666667, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550770, Length=192, Percent_Identity=27.6041666666667, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45551930, Length=192, Percent_Identity=27.6041666666667, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35944; Mature: 35944

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLLEEPAKLSLAEVDTPSCPKGGVLLEVACCAICGTDVKMFRRGHRDLKYPRILGHE
CCCEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHH
IAAVVACSEHPDFKAGDRVQVYPGIACGVCPLCLQGRENLCGQVKIIGFNYDGGLAEYMA
HEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHC
LPPESLPGGLNIIPENVSDEEASLAEPLASCIHSQSVSRVGDGDRVLVLGAGPLGLLQAM
CCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
LARHNGAEKVLMAEVLPDRVCGAELACPDGVIDLAKTSLRQGVFEQTGGAGVDVILIASS
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GVEVGELPSVLSPGGRINFFSGLPKDRSEFSLDANTIHYRELALSGSYGSTPADNTRALS
CCCCCCCCHHHCCCCCEEECCCCCCCCHHCCCCCCEEEEEEEEEECCCCCCCCCCCEEEH
LITDGIIPVKRLISRVTGISDIEEAFLGVEKLKGLKTIIKF
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAVLLEEPAKLSLAEVDTPSCPKGGVLLEVACCAICGTDVKMFRRGHRDLKYPRILGHE
CCCEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHH
IAAVVACSEHPDFKAGDRVQVYPGIACGVCPLCLQGRENLCGQVKIIGFNYDGGLAEYMA
HEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHC
LPPESLPGGLNIIPENVSDEEASLAEPLASCIHSQSVSRVGDGDRVLVLGAGPLGLLQAM
CCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
LARHNGAEKVLMAEVLPDRVCGAELACPDGVIDLAKTSLRQGVFEQTGGAGVDVILIASS
HHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GVEVGELPSVLSPGGRINFFSGLPKDRSEFSLDANTIHYRELALSGSYGSTPADNTRALS
CCCCCCCCHHHCCCCCEEECCCCCCCCHHCCCCCCEEEEEEEEEECCCCCCCCCCCEEEH
LITDGIIPVKRLISRVTGISDIEEAFLGVEKLKGLKTIIKF
HHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]