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The map label for this gene is trpD-1 [H]

Identifier: 57235046

GI number: 57235046

Start: 123885

End: 125009

Strand: Direct

Name: trpD-1 [H]

Synonym: DET0126

Alternate gene names: 57235046

Gene position: 123885-125009 (Clockwise)

Preceding gene: 57235047

Following gene: 57235029

Centisome position: 8.43

GC content: 53.42

Gene sequence:

>1125_bases
GTGGACGAAAACAGGGTAAAAAATTTCGGGGCTGTCATAAGCCGCCTTATTTCAAAGGAAAATCTTAACCGTGAAGAAGT
AAAAGACTGTTTCTGCCAGATAATGCGGAATGAACAGCCTGACCTCCAGCAGGGTGCCTTTATGGCCGCCCTAACCGCCA
AGGGTGAAACAGCACCGGAGATAGCCGGTGTCTGGGAAGCTATATATGAGCAGGATACGGTAAGGGTTAAGCCTTTGGTA
AATAAACCTTTGGTGGATAACTGCGGTACGGGCATGGACAGCCTGAAGACCTTTAACATCAGCACGGCTGCTTCCATTGT
GGCGGCGGCGGGCGGGGTGGTACTGGCAAAACACGGTGCCAGAGCCCTTTCCGGCAGCTTAGGGACTATTGATATGCTGG
AATCACTGGGTGTTGACGTGGAAACAGACGTGGAGACCGTCAGGCGGAGTATTGAAACGGCGGGTATAGGCATTTTTAAC
GGCATGAGCGCCAAAGTTCACCCCCAGGCTCTTTTCCGTATCCTTTCCCAGATACGTTTCGGGACTACCCTTAATATTGC
CGGTTCGCTGGCAAACCCGGCTTTGCCCCGTTATGCGGTCAGGGGGGTATATTCAGCCGAACTATTGCAGCCGGTGGCCG
AGGTGATGCGTGAGATAGGTTATAAAAAAGCCCTGGTTATCTACGGCTCTGCCCCCGGCGGCCGGGGAATGGATGAACTT
TCCGTTTTGGGCGAAAGCCGCATTGCCGAGCTTGGCGAAGACGGGCAGATTATTAACTACAGCTTGTCTCCGGCAGATTT
TGGTTTAAAACCCGGCCGGACGGAGGATATTCTTACTTCGGGTGATAAACAACGCGAAACCCTGCGGCTTCTCCGTATTC
TTTCTGGCGGTGAAAACGGGGCTGCTTTTAACGCGGTTTGTCTGAATGCCGCTCCTGTTTTTTATATAGCCGGTGAGGCT
GACAGCCTTCAGCAGGGTTATGCTAAAGCGGCGGAGATAATCCGTTCCGGTGCGGCTATTGCCAAGCTCCGGCAGTGGGT
GCAGACCCAGAATTCCAACCCCCAAGCCGGTCTTGCCCGGCTGGACAGCCTGCTGGCTGAACTGGACGGAACAAAGGTCA
GCTAA

Upstream 100 bases:

>100_bases
TAACGGGTATTTCAGATATAGAGGAGGCTTTTCTGGGGGTGGAAAAGCTAAAAGGCCTTAAAACCATTATCAAATTTTAA
TAAAAAAGAGGGAAACAAAA

Downstream 100 bases:

>100_bases
GGGTATTTATTTGGGGAAATTTAAAAGCTGGCTTAGAGTGAATCGGTGCTGTTTTTGCAAGCCCACTTGGCTTGCGGGAG
AGGTTTAACCCGGGATGACT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MDENRVKNFGAVISRLISKENLNREEVKDCFCQIMRNEQPDLQQGAFMAALTAKGETAPEIAGVWEAIYEQDTVRVKPLV
NKPLVDNCGTGMDSLKTFNISTAASIVAAAGGVVLAKHGARALSGSLGTIDMLESLGVDVETDVETVRRSIETAGIGIFN
GMSAKVHPQALFRILSQIRFGTTLNIAGSLANPALPRYAVRGVYSAELLQPVAEVMREIGYKKALVIYGSAPGGRGMDEL
SVLGESRIAELGEDGQIINYSLSPADFGLKPGRTEDILTSGDKQRETLRLLRILSGGENGAAFNAVCLNAAPVFYIAGEA
DSLQQGYAKAAEIIRSGAAIAKLRQWVQTQNSNPQAGLARLDSLLAELDGTKVS

Sequences:

>Translated_374_residues
MDENRVKNFGAVISRLISKENLNREEVKDCFCQIMRNEQPDLQQGAFMAALTAKGETAPEIAGVWEAIYEQDTVRVKPLV
NKPLVDNCGTGMDSLKTFNISTAASIVAAAGGVVLAKHGARALSGSLGTIDMLESLGVDVETDVETVRRSIETAGIGIFN
GMSAKVHPQALFRILSQIRFGTTLNIAGSLANPALPRYAVRGVYSAELLQPVAEVMREIGYKKALVIYGSAPGGRGMDEL
SVLGESRIAELGEDGQIINYSLSPADFGLKPGRTEDILTSGDKQRETLRLLRILSGGENGAAFNAVCLNAAPVFYIAGEA
DSLQQGYAKAAEIIRSGAAIAKLRQWVQTQNSNPQAGLARLDSLLAELDGTKVS
>Mature_374_residues
MDENRVKNFGAVISRLISKENLNREEVKDCFCQIMRNEQPDLQQGAFMAALTAKGETAPEIAGVWEAIYEQDTVRVKPLV
NKPLVDNCGTGMDSLKTFNISTAASIVAAAGGVVLAKHGARALSGSLGTIDMLESLGVDVETDVETVRRSIETAGIGIFN
GMSAKVHPQALFRILSQIRFGTTLNIAGSLANPALPRYAVRGVYSAELLQPVAEVMREIGYKKALVIYGSAPGGRGMDEL
SVLGESRIAELGEDGQIINYSLSPADFGLKPGRTEDILTSGDKQRETLRLLRILSGGENGAAFNAVCLNAAPVFYIAGEA
DSLQQGYAKAAEIIRSGAAIAKLRQWVQTQNSNPQAGLARLDSLLAELDGTKVS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=332, Percent_Identity=32.2289156626506, Blast_Score=152, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6320561, Length=370, Percent_Identity=25.9459459459459, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 39869; Mature: 39869

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDENRVKNFGAVISRLISKENLNREEVKDCFCQIMRNEQPDLQQGAFMAALTAKGETAPE
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCHH
IAGVWEAIYEQDTVRVKPLVNKPLVDNCGTGMDSLKTFNISTAASIVAAAGGVVLAKHGA
HHHHHHHHHCCCCEEECCCCCCCCHHHCCCCHHHHEEECCHHHHHHHHHCCCEEEECCCC
RALSGSLGTIDMLESLGVDVETDVETVRRSIETAGIGIFNGMSAKVHPQALFRILSQIRF
HHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHC
GTTLNIAGSLANPALPRYAVRGVYSAELLQPVAEVMREIGYKKALVIYGSAPGGRGMDEL
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHH
SVLGESRIAELGEDGQIINYSLSPADFGLKPGRTEDILTSGDKQRETLRLLRILSGGENG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCC
AAFNAVCLNAAPVFYIAGEADSLQQGYAKAAEIIRSGAAIAKLRQWVQTQNSNPQAGLAR
CEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHH
LDSLLAELDGTKVS
HHHHHHHCCCCCCC
>Mature Secondary Structure
MDENRVKNFGAVISRLISKENLNREEVKDCFCQIMRNEQPDLQQGAFMAALTAKGETAPE
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHCCEEEEEECCCCCCHH
IAGVWEAIYEQDTVRVKPLVNKPLVDNCGTGMDSLKTFNISTAASIVAAAGGVVLAKHGA
HHHHHHHHHCCCCEEECCCCCCCCHHHCCCCHHHHEEECCHHHHHHHHHCCCEEEECCCC
RALSGSLGTIDMLESLGVDVETDVETVRRSIETAGIGIFNGMSAKVHPQALFRILSQIRF
HHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHC
GTTLNIAGSLANPALPRYAVRGVYSAELLQPVAEVMREIGYKKALVIYGSAPGGRGMDEL
CCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHH
SVLGESRIAELGEDGQIINYSLSPADFGLKPGRTEDILTSGDKQRETLRLLRILSGGENG
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCC
AAFNAVCLNAAPVFYIAGEADSLQQGYAKAAEIIRSGAAIAKLRQWVQTQNSNPQAGLAR
CEEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHH
LDSLLAELDGTKVS
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA