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The map label for this gene is kamA [H]

Identifier: 57234982

GI number: 57234982

Start: 212825

End: 214951

Strand: Direct

Name: kamA [H]

Synonym: DET0221

Alternate gene names: 57234982

Gene position: 212825-214951 (Clockwise)

Preceding gene: 57234992

Following gene: 57234980

Centisome position: 14.48

GC content: 51.2

Gene sequence:

>2127_bases
ATGGCCCACAAGATAAGCTCTGACTACAGTGAGGAAGAGTGGGGGAACTGGAAATGGCATGTTTCCCATACTATTAAGGA
CTTGGCTACCGTTGAAAAACTGCTGGGGGTGAAATTTTCAGTTGAAAAACGCCGCAGTCTGGAAGATACTATCCGCAATT
TCCCCATGAGTATTACCCCGTATTACTTTTCCCTGATTGACCCCAAAAATTTTGAAAATGACCCGGTTTTTATTCAGTCT
GTACCCAGTGCCGCCGAGCTTAATTTCAGCTGCCATGATAAGGAAGACCCACTGGCTGAAGATGTGGACAGCCCCGCCCC
CGGCATTACCCACCGCTATCCTGACAGGGTGCTGTTTCATGTTTCAAACCGCTGTGCCATGTACTGCCGCCACTGTACCC
GCAAACGTAAAGTGGGGGATGTTGACAAGACCCTGTCCCGTGATGACCTGGTAAAGGGCTTGGAATATATCAAAAATACC
CCCCAGGTTCGGGATGTGCTGCTATCCGGGGGTGACCCCCTGCTGCTTTCAGACAGTATGCTTGAGTGGCTGCTGTCTGA
GCTGAAGGCCATACCCCATGTTCAGGTAATACGCATCGGCACACGGGTGCCGGTGGTACTGCCCCAGCGGATTACCCCCC
ATCTGGTAAAAATCATTAAAAAATACCACCCTGTCTGGGTAAATACCCACTTCAACCACCCCAGAGAGATTACTGCTACC
TCTATCCGGGCGCTTCGCCTGCTGGCGGATGCCGGTATCCCGCTGGGTAACCAGACCGTCCTGCTGGCCAAAGTAAATGA
CTGCCCACGGGTTATGAAGGCTCTGGTGCACAAACTGGTGGAAAACAGGGTAAGGCCTTATTACCTGTATCAGTGTGACC
CGGCGCAGGGGCTTTCCCATTTCCGCACTTCCATAGGCAAGGGGATAGAGATTATTGAAAATCTTATCGGGCATACCAGC
GGTTTCGCTGTGCCTACCTATGTAATAGACGCCCCCAACGGCGGCGGCAAGATACCCATTATGCCGAATTACCTGATATC
CCAGTCCTCCAGCAAGGTTATCCTGCGTAATTACGAAGGGATTATAACCGCCTATTACCAGCCGGAAGACTATCACCCGC
CCAAGTGCGGCCAGGACTGTTCGGCCTGTAACCTTGAGCTTGATTTAAACGGTGCGGCCGAAGGGTCACTGGTGGGCATT
GCCCGCTTGCTTTCAAATCATGAAGACACTGATTATTTAGTCCCCACCGAATGTGACCGGATGGACCGCCGCAAGAGCGG
TTATGACCAGATAGTCACTCTGGGTACGTCTTTGATTCAGCACGGCAAAAACAGTGACCGTATTTACCTGATGCGGCTGG
CTGCCGAGGAAACCGCTACCCTGCTGCCTGAAATGCAATCACTGGCCGCTGAAAACGGCTATACCAAGCTGTTTGCCAAA
GTGCCCGGTGATGTTAAAACCCTGTTTGAGGCAGACGGTTTTGAAACCGAAGCGGTTATTCCCTGTTTTTACGGCGGGAC
TAAGGCCGGTTATTTTATGGGCAAATTTATAGATGAGGGCAGGAAAACAGAGGAAAATGCCGAATTGCTGGAAGATGTGC
TGAAGGTGGCCCATTCCAAAGCCGGTAAGGCACTTTCGTTTAAACTGCCTAGGGGATACACCCTTCGCAAATGCACTGCT
GACGATACTGCGGCCATGGCCGAGGTGTTTTCCACTGTATTTGCCTCATACCCGTTCCCTATTTACGAACCGGAATATAT
CAGCCGCACCATGACCGAGAGTATAACCTATTATGGTATCTGGCACGGGCAGAAACTGGCGGCGCTGGCTTCGGCTGAGC
AGTATCCGCTGGAAGGCCATGTGGAACTGACAGATTTCGCCACCCTGCCGGATTACCGCCGCCGCAAGCTGGCGGGTATC
TTGCTGCATACTATGGAAACCGAAATGAAACAAAAAGGTTTCGGGGTAAGCTATACGTCTGCGGTGGCAGAGTCTTACGG
TATGAATATAAGCTTTGCCAGACAGGGGTATGAGTTTGCCGGCCGGCTTAAGAATAATACCCAGATAAACGGCGGCCTGA
AAAGCATGAATATCTGGTACAAATGCCTGAAGAAACAGACTAAATAA

Upstream 100 bases:

>100_bases
GTTGGGGTGTATCCCGCACAAAGGAAGGATTAACATGGTTTTAACACATATTGAAGAAAAGATGCCCCAGACCTCTTTGC
CGGAGCATGATTACCGCCTG

Downstream 100 bases:

>100_bases
GCCGGATTTTTATGGCATTATATAAGAAAGCGGGCACCCCTGAGAGGTGTCCGCTCTTTTTCTTACAGACTGGTATTATT
TCAGGCGGTGGGGTCTATTA

Product: GNAT family L-lysine 2,3-aminomutase/acetyltransferase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 708; Mature: 707

Protein sequence:

>708_residues
MAHKISSDYSEEEWGNWKWHVSHTIKDLATVEKLLGVKFSVEKRRSLEDTIRNFPMSITPYYFSLIDPKNFENDPVFIQS
VPSAAELNFSCHDKEDPLAEDVDSPAPGITHRYPDRVLFHVSNRCAMYCRHCTRKRKVGDVDKTLSRDDLVKGLEYIKNT
PQVRDVLLSGGDPLLLSDSMLEWLLSELKAIPHVQVIRIGTRVPVVLPQRITPHLVKIIKKYHPVWVNTHFNHPREITAT
SIRALRLLADAGIPLGNQTVLLAKVNDCPRVMKALVHKLVENRVRPYYLYQCDPAQGLSHFRTSIGKGIEIIENLIGHTS
GFAVPTYVIDAPNGGGKIPIMPNYLISQSSSKVILRNYEGIITAYYQPEDYHPPKCGQDCSACNLELDLNGAAEGSLVGI
ARLLSNHEDTDYLVPTECDRMDRRKSGYDQIVTLGTSLIQHGKNSDRIYLMRLAAEETATLLPEMQSLAAENGYTKLFAK
VPGDVKTLFEADGFETEAVIPCFYGGTKAGYFMGKFIDEGRKTEENAELLEDVLKVAHSKAGKALSFKLPRGYTLRKCTA
DDTAAMAEVFSTVFASYPFPIYEPEYISRTMTESITYYGIWHGQKLAALASAEQYPLEGHVELTDFATLPDYRRRKLAGI
LLHTMETEMKQKGFGVSYTSAVAESYGMNISFARQGYEFAGRLKNNTQINGGLKSMNIWYKCLKKQTK

Sequences:

>Translated_708_residues
MAHKISSDYSEEEWGNWKWHVSHTIKDLATVEKLLGVKFSVEKRRSLEDTIRNFPMSITPYYFSLIDPKNFENDPVFIQS
VPSAAELNFSCHDKEDPLAEDVDSPAPGITHRYPDRVLFHVSNRCAMYCRHCTRKRKVGDVDKTLSRDDLVKGLEYIKNT
PQVRDVLLSGGDPLLLSDSMLEWLLSELKAIPHVQVIRIGTRVPVVLPQRITPHLVKIIKKYHPVWVNTHFNHPREITAT
SIRALRLLADAGIPLGNQTVLLAKVNDCPRVMKALVHKLVENRVRPYYLYQCDPAQGLSHFRTSIGKGIEIIENLIGHTS
GFAVPTYVIDAPNGGGKIPIMPNYLISQSSSKVILRNYEGIITAYYQPEDYHPPKCGQDCSACNLELDLNGAAEGSLVGI
ARLLSNHEDTDYLVPTECDRMDRRKSGYDQIVTLGTSLIQHGKNSDRIYLMRLAAEETATLLPEMQSLAAENGYTKLFAK
VPGDVKTLFEADGFETEAVIPCFYGGTKAGYFMGKFIDEGRKTEENAELLEDVLKVAHSKAGKALSFKLPRGYTLRKCTA
DDTAAMAEVFSTVFASYPFPIYEPEYISRTMTESITYYGIWHGQKLAALASAEQYPLEGHVELTDFATLPDYRRRKLAGI
LLHTMETEMKQKGFGVSYTSAVAESYGMNISFARQGYEFAGRLKNNTQINGGLKSMNIWYKCLKKQTK
>Mature_707_residues
AHKISSDYSEEEWGNWKWHVSHTIKDLATVEKLLGVKFSVEKRRSLEDTIRNFPMSITPYYFSLIDPKNFENDPVFIQSV
PSAAELNFSCHDKEDPLAEDVDSPAPGITHRYPDRVLFHVSNRCAMYCRHCTRKRKVGDVDKTLSRDDLVKGLEYIKNTP
QVRDVLLSGGDPLLLSDSMLEWLLSELKAIPHVQVIRIGTRVPVVLPQRITPHLVKIIKKYHPVWVNTHFNHPREITATS
IRALRLLADAGIPLGNQTVLLAKVNDCPRVMKALVHKLVENRVRPYYLYQCDPAQGLSHFRTSIGKGIEIIENLIGHTSG
FAVPTYVIDAPNGGGKIPIMPNYLISQSSSKVILRNYEGIITAYYQPEDYHPPKCGQDCSACNLELDLNGAAEGSLVGIA
RLLSNHEDTDYLVPTECDRMDRRKSGYDQIVTLGTSLIQHGKNSDRIYLMRLAAEETATLLPEMQSLAAENGYTKLFAKV
PGDVKTLFEADGFETEAVIPCFYGGTKAGYFMGKFIDEGRKTEENAELLEDVLKVAHSKAGKALSFKLPRGYTLRKCTAD
DTAAMAEVFSTVFASYPFPIYEPEYISRTMTESITYYGIWHGQKLAALASAEQYPLEGHVELTDFATLPDYRRRKLAGIL
LHTMETEMKQKGFGVSYTSAVAESYGMNISFARQGYEFAGRLKNNTQINGGLKSMNIWYKCLKKQTK

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=341, Percent_Identity=30.791788856305, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 79605; Mature: 79474

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHKISSDYSEEEWGNWKWHVSHTIKDLATVEKLLGVKFSVEKRRSLEDTIRNFPMSITP
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECC
YYFSLIDPKNFENDPVFIQSVPSAAELNFSCHDKEDPLAEDVDSPAPGITHRYPDRVLFH
CEEEEECCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEE
VSNRCAMYCRHCTRKRKVGDVDKTLSRDDLVKGLEYIKNTPQVRDVLLSGGDPLLLSDSM
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECHHH
LEWLLSELKAIPHVQVIRIGTRVPVVLPQRITPHLVKIIKKYHPVWVNTHFNHPREITAT
HHHHHHHHHHCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHCCEEEECCCCCCCHHHHH
SIRALRLLADAGIPLGNQTVLLAKVNDCPRVMKALVHKLVENRVRPYYLYQCDPAQGLSH
HHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
FRTSIGKGIEIIENLIGHTSGFAVPTYVIDAPNGGGKIPIMPNYLISQSSSKVILRNYEG
HHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCEEEEEECCC
IITAYYQPEDYHPPKCGQDCSACNLELDLNGAAEGSLVGIARLLSNHEDTDYLVPTECDR
EEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEECCCCHHH
MDRRKSGYDQIVTLGTSLIQHGKNSDRIYLMRLAAEETATLLPEMQSLAAENGYTKLFAK
HHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEE
VPGDVKTLFEADGFETEAVIPCFYGGTKAGYFMGKFIDEGRKTEENAELLEDVLKVAHSK
CCCHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
AGKALSFKLPRGYTLRKCTADDTAAMAEVFSTVFASYPFPIYEPEYISRTMTESITYYGI
CCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCEEEEEE
WHGQKLAALASAEQYPLEGHVELTDFATLPDYRRRKLAGILLHTMETEMKQKGFGVSYTS
ECCCHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AVAESYGMNISFARQGYEFAGRLKNNTQINGGLKSMNIWYKCLKKQTK
HHHHHHCCCEEEHHCCHHHHHHCCCCCEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHKISSDYSEEEWGNWKWHVSHTIKDLATVEKLLGVKFSVEKRRSLEDTIRNFPMSITP
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEECC
YYFSLIDPKNFENDPVFIQSVPSAAELNFSCHDKEDPLAEDVDSPAPGITHRYPDRVLFH
CEEEEECCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCEEEE
VSNRCAMYCRHCTRKRKVGDVDKTLSRDDLVKGLEYIKNTPQVRDVLLSGGDPLLLSDSM
HHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECHHH
LEWLLSELKAIPHVQVIRIGTRVPVVLPQRITPHLVKIIKKYHPVWVNTHFNHPREITAT
HHHHHHHHHHCCCEEEEEECCCCCEEECCCCCHHHHHHHHHHCCEEEECCCCCCCHHHHH
SIRALRLLADAGIPLGNQTVLLAKVNDCPRVMKALVHKLVENRVRPYYLYQCDPAQGLSH
HHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHH
FRTSIGKGIEIIENLIGHTSGFAVPTYVIDAPNGGGKIPIMPNYLISQSSSKVILRNYEG
HHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCEEEEEECCC
IITAYYQPEDYHPPKCGQDCSACNLELDLNGAAEGSLVGIARLLSNHEDTDYLVPTECDR
EEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEECCCCHHH
MDRRKSGYDQIVTLGTSLIQHGKNSDRIYLMRLAAEETATLLPEMQSLAAENGYTKLFAK
HHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCCEEEEEE
VPGDVKTLFEADGFETEAVIPCFYGGTKAGYFMGKFIDEGRKTEENAELLEDVLKVAHSK
CCCHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHC
AGKALSFKLPRGYTLRKCTADDTAAMAEVFSTVFASYPFPIYEPEYISRTMTESITYYGI
CCCEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCEEEEEE
WHGQKLAALASAEQYPLEGHVELTDFATLPDYRRRKLAGILLHTMETEMKQKGFGVSYTS
ECCCHHHHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
AVAESYGMNISFARQGYEFAGRLKNNTQINGGLKSMNIWYKCLKKQTK
HHHHHHCCCEEEHHCCHHHHHHCCCCCEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]