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The map label for this gene is aroB [H]

Identifier: 57234788

GI number: 57234788

Start: 379397

End: 380491

Strand: Direct

Name: aroB [H]

Synonym: DET0400

Alternate gene names: 57234788

Gene position: 379397-380491 (Clockwise)

Preceding gene: 57234789

Following gene: 57234787

Centisome position: 25.81

GC content: 47.4

Gene sequence:

>1095_bases
ATGGGTAAAGTGGATACACTGGCTTATGACATTGGGAATAACCGTACCCGCCACGTATATATAGGCAGTGACATACTGGG
TAGTCTGCCCGAATATGCAAAACAGCTAAATGCGGACAAATTTTTTATAATAACTGATTCCAATCTGGAAAATATTCTAA
AAGATAAAATAAAAGATTTGCTTTCCGGGGTGACCGAAACCCACCTGCTGGCTTTCCCGGCCGGTGAAGCCTCAAAAACT
CTGTCTACTCTGGAAGACATAGGCTCAAAAATCCTTGACCTCAGGGCTACCAAATCAAGCGTTATCGTCTGTTTGGGGGG
TGGGGTAGTAGGGAATCTGGGCGGTCTTACCGCCGCACTCCTTTTCAGGGGTTTGCGCTTTTTCCATATTCCTACCACCA
TGGTTGCCCAGATAGACAGTGCCATTGGCCAGAAACAGGCCGTTAACTACAAAATGGGTAAAAACCTGTTCGGACAGTAT
TATGCCCCTGAGTTTGTCTTTATAGATTTTAATTTCCTGCGGACTCTGCCCGAACGCCAGATACGGGCGGGTTTGGCCGA
ATCTGTAAAACACGGCTTGTGCCAGGAATCCTCCTTTTTTGACTATATAGAAGAACACGCCGGTGATTATTCGCCGGAAG
TTATAGATTATATCTCCCGCCATACCATAGAGCTTAAGCTGGAGCTGCTTAAGATTGACCCCTTTGAGGGCAAGCTTGAC
CCCCAGCTGGAGCTTGGGCATACCATAGGCCATGCGGTAGAGATTATTAAAAACGGCCAGCTTTTGCATGGTGAGTCCAT
TGCTATCGGCATGGTGGCTGAGGCCGCCCTTTCCTGTGAGATGGGCTATATGAAGCCCGAACTGGCCGCTAAAATAGAGC
GTATTTTCAAGAAGCTGGGTTTGCCCACCCGTATTCCGGCGGATGTTCCTCTGGAAGGGGTGCTGGAAGCCCTGCGCTAT
GATAACAAACGCCGTACTGCCCGTACAGACTTCTTTTTGCTTGAGGATTTTACCCGTTTCCACAAGGAAAATGGTAAAAT
AGGTACCAAGGTTTCTGAAGAGGTTTTGAAGAAAGTTCTTGAAAGCGCTTACTAG

Upstream 100 bases:

>100_bases
ATGTCTATCCTCCAGAATCAGGGTTTTATAAATATCAAATCCCGCTATCAGAGCGGTGGTATGGGTACACTGACCGTGGC
CTATAAGCCGGAGAATTAAA

Downstream 100 bases:

>100_bases
CGAACGTCCGGATTTTCAGGACTGGATACAGGCTGCCCGTCTCAAGTTCCTGCCCCAGGGTGTAATGCCGGTGGTAATAG
CCGGCGCTTTGGCTTTTTCT

Product: 3-dehydroquinate synthase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MGKVDTLAYDIGNNRTRHVYIGSDILGSLPEYAKQLNADKFFIITDSNLENILKDKIKDLLSGVTETHLLAFPAGEASKT
LSTLEDIGSKILDLRATKSSVIVCLGGGVVGNLGGLTAALLFRGLRFFHIPTTMVAQIDSAIGQKQAVNYKMGKNLFGQY
YAPEFVFIDFNFLRTLPERQIRAGLAESVKHGLCQESSFFDYIEEHAGDYSPEVIDYISRHTIELKLELLKIDPFEGKLD
PQLELGHTIGHAVEIIKNGQLLHGESIAIGMVAEAALSCEMGYMKPELAAKIERIFKKLGLPTRIPADVPLEGVLEALRY
DNKRRTARTDFFLLEDFTRFHKENGKIGTKVSEEVLKKVLESAY

Sequences:

>Translated_364_residues
MGKVDTLAYDIGNNRTRHVYIGSDILGSLPEYAKQLNADKFFIITDSNLENILKDKIKDLLSGVTETHLLAFPAGEASKT
LSTLEDIGSKILDLRATKSSVIVCLGGGVVGNLGGLTAALLFRGLRFFHIPTTMVAQIDSAIGQKQAVNYKMGKNLFGQY
YAPEFVFIDFNFLRTLPERQIRAGLAESVKHGLCQESSFFDYIEEHAGDYSPEVIDYISRHTIELKLELLKIDPFEGKLD
PQLELGHTIGHAVEIIKNGQLLHGESIAIGMVAEAALSCEMGYMKPELAAKIERIFKKLGLPTRIPADVPLEGVLEALRY
DNKRRTARTDFFLLEDFTRFHKENGKIGTKVSEEVLKKVLESAY
>Mature_363_residues
GKVDTLAYDIGNNRTRHVYIGSDILGSLPEYAKQLNADKFFIITDSNLENILKDKIKDLLSGVTETHLLAFPAGEASKTL
STLEDIGSKILDLRATKSSVIVCLGGGVVGNLGGLTAALLFRGLRFFHIPTTMVAQIDSAIGQKQAVNYKMGKNLFGQYY
APEFVFIDFNFLRTLPERQIRAGLAESVKHGLCQESSFFDYIEEHAGDYSPEVIDYISRHTIELKLELLKIDPFEGKLDP
QLELGHTIGHAVEIIKNGQLLHGESIAIGMVAEAALSCEMGYMKPELAAKIERIFKKLGLPTRIPADVPLEGVLEALRYD
NKRRTARTDFFLLEDFTRFHKENGKIGTKVSEEVLKKVLESAY

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=315, Percent_Identity=33.6507936507937, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6320332, Length=406, Percent_Identity=29.3103448275862, Blast_Score=163, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 40455; Mature: 40324

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVDTLAYDIGNNRTRHVYIGSDILGSLPEYAKQLNADKFFIITDSNLENILKDKIKDL
CCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
LSGVTETHLLAFPAGEASKTLSTLEDIGSKILDLRATKSSVIVCLGGGVVGNLGGLTAAL
HHCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHHHHHHHHH
LFRGLRFFHIPTTMVAQIDSAIGQKQAVNYKMGKNLFGQYYAPEFVFIDFNFLRTLPERQ
HHHCHHHEECCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHCHHHH
IRAGLAESVKHGLCQESSFFDYIEEHAGDYSPEVIDYISRHTIELKLELLKIDPFEGKLD
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCEEEEEEEEEEECCCCCCCC
PQLELGHTIGHAVEIIKNGQLLHGESIAIGMVAEAALSCEMGYMKPELAAKIERIFKKLG
CCHHHHHHHHHHHHHHHCCCEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
LPTRIPADVPLEGVLEALRYDNKRRTARTDFFLLEDFTRFHKENGKIGTKVSEEVLKKVL
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ESAY
HHCC
>Mature Secondary Structure 
GKVDTLAYDIGNNRTRHVYIGSDILGSLPEYAKQLNADKFFIITDSNLENILKDKIKDL
CCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
LSGVTETHLLAFPAGEASKTLSTLEDIGSKILDLRATKSSVIVCLGGGVVGNLGGLTAAL
HHCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCHHHHHHHHHHHH
LFRGLRFFHIPTTMVAQIDSAIGQKQAVNYKMGKNLFGQYYAPEFVFIDFNFLRTLPERQ
HHHCHHHEECCHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHCHHHH
IRAGLAESVKHGLCQESSFFDYIEEHAGDYSPEVIDYISRHTIELKLELLKIDPFEGKLD
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCEEEEEEEEEEECCCCCCCC
PQLELGHTIGHAVEIIKNGQLLHGESIAIGMVAEAALSCEMGYMKPELAAKIERIFKKLG
CCHHHHHHHHHHHHHHHCCCEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
LPTRIPADVPLEGVLEALRYDNKRRTARTDFFLLEDFTRFHKENGKIGTKVSEEVLKKVL
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
ESAY
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA