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The map label for this gene is coaX [H]

Identifier: 57234779

GI number: 57234779

Start: 400891

End: 401667

Strand: Direct

Name: coaX [H]

Synonym: DET0428

Alternate gene names: 57234779

Gene position: 400891-401667 (Clockwise)

Preceding gene: 57234780

Following gene: 57234778

Centisome position: 27.28

GC content: 51.35

Gene sequence:

>777_bases
ATGTCTGAAAAACTGGTGGCGGTAGATATCGGCAATACCAGCGTAAATATAGGTATATTTGAGGGCGAAAAACTGCTGGC
AAACTGGCATCTGGGTTCGGTTGCCCAGCGTATGGCTGATGAATATGCCAGTCTGCTCTTAGGCCTGTTGCAGCACGCCG
GTATACACCCGGAAGAGCTAAACAGGGTAATCATGTGCAGTGTTGTGCCGCCCCTGACCACTACTTTTGAAGAGGTATTT
AAAAGCTATTTCAAGGCTGCTCCTCTGGTAGTGGGTGCAGGTATAAAGAGCGGGGTTAAGGTGCGCATGGATAACCCCCG
TGAGGTTGGGGCTGACCGCATAGTAAATGCCGCTGCCGCCAGGGTGCTTTATCCGGGGGCGTGCATAATAGTGGACATGG
GTACGGCCACTACCTTTGATACCCTTTCCGAGGGTGGGGCATATATAGGCGGGGCGATTGCACCCGGTATTGCCACCTCA
GCCCAGGCTATTGCGGAAAAGACTTCAAAACTGCCCAAGATTGAGATAATCCGTCCTGCCAAAGTTATCGGCTCTAATAC
TGTGTCGGCTATGCAGTCAGGTATATACTTCGGTTATATCGGGCTGGTGGAAGAGCTGGTCAGGCGGATTCAAACTGAAT
TGGGGCAGAAAACCAGAGTTGTGGCTACCGGCGGTTATGCCGCGCTTATAGCCGAAGGCAGCCGTATTTTTGATATTGTC
CGCCCTGACCTTACCCTTCAGGGACTCAGGATTATTTACCAGATGAATCAGGCTTAG

Upstream 100 bases:

>100_bases
GAGTGAAATGGGTGATGCCGGTGTACTGGCTTCGGATCTGCTGTTAAAATTGCCTGCGGTTATAAAAGAATTGAAACAGA
GCTGAGAGATGGATAAACAA

Downstream 100 bases:

>100_bases
TTATCGGTGTATATTAAAAGCAGGAATGTAGGCTGCGGTAAGAGCCTTACTGCTTAAGGGATACTAGCTGAAAAGACTTG
CCGGGGGGAGTGCAGACGGA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSEKLVAVDIGNTSVNIGIFEGEKLLANWHLGSVAQRMADEYASLLLGLLQHAGIHPEELNRVIMCSVVPPLTTTFEEVF
KSYFKAAPLVVGAGIKSGVKVRMDNPREVGADRIVNAAAARVLYPGACIIVDMGTATTFDTLSEGGAYIGGAIAPGIATS
AQAIAEKTSKLPKIEIIRPAKVIGSNTVSAMQSGIYFGYIGLVEELVRRIQTELGQKTRVVATGGYAALIAEGSRIFDIV
RPDLTLQGLRIIYQMNQA

Sequences:

>Translated_258_residues
MSEKLVAVDIGNTSVNIGIFEGEKLLANWHLGSVAQRMADEYASLLLGLLQHAGIHPEELNRVIMCSVVPPLTTTFEEVF
KSYFKAAPLVVGAGIKSGVKVRMDNPREVGADRIVNAAAARVLYPGACIIVDMGTATTFDTLSEGGAYIGGAIAPGIATS
AQAIAEKTSKLPKIEIIRPAKVIGSNTVSAMQSGIYFGYIGLVEELVRRIQTELGQKTRVVATGGYAALIAEGSRIFDIV
RPDLTLQGLRIIYQMNQA
>Mature_257_residues
SEKLVAVDIGNTSVNIGIFEGEKLLANWHLGSVAQRMADEYASLLLGLLQHAGIHPEELNRVIMCSVVPPLTTTFEEVFK
SYFKAAPLVVGAGIKSGVKVRMDNPREVGADRIVNAAAARVLYPGACIIVDMGTATTFDTLSEGGAYIGGAIAPGIATSA
QAIAEKTSKLPKIEIIRPAKVIGSNTVSAMQSGIYFGYIGLVEELVRRIQTELGQKTRVVATGGYAALIAEGSRIFDIVR
PDLTLQGLRIIYQMNQA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 27490; Mature: 27359

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKLVAVDIGNTSVNIGIFEGEKLLANWHLGSVAQRMADEYASLLLGLLQHAGIHPEEL
CCCCEEEEEECCCEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
NRVIMCSVVPPLTTTFEEVFKSYFKAAPLVVGAGIKSGVKVRMDNPREVGADRIVNAAAA
CEEEEEECCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHH
RVLYPGACIIVDMGTATTFDTLSEGGAYIGGAIAPGIATSAQAIAEKTSKLPKIEIIRPA
HHCCCCEEEEEECCCCCCHHHHHCCCCEECCHHCCCHHHHHHHHHHHHHCCCCEEEECCH
KVIGSNTVSAMQSGIYFGYIGLVEELVRRIQTELGQKTRVVATGGYAALIAEGSRIFDIV
HHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCEEEEC
RPDLTLQGLRIIYQMNQA
CCCCHHHHHHHEEEECCC
>Mature Secondary Structure 
SEKLVAVDIGNTSVNIGIFEGEKLLANWHLGSVAQRMADEYASLLLGLLQHAGIHPEEL
CCCEEEEEECCCEEEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHC
NRVIMCSVVPPLTTTFEEVFKSYFKAAPLVVGAGIKSGVKVRMDNPREVGADRIVNAAAA
CEEEEEECCCCHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHH
RVLYPGACIIVDMGTATTFDTLSEGGAYIGGAIAPGIATSAQAIAEKTSKLPKIEIIRPA
HHCCCCEEEEEECCCCCCHHHHHCCCCEECCHHCCCHHHHHHHHHHHHHCCCCEEEECCH
KVIGSNTVSAMQSGIYFGYIGLVEELVRRIQTELGQKTRVVATGGYAALIAEGSRIFDIV
HHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCEEEEC
RPDLTLQGLRIIYQMNQA
CCCCHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA