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The map label for this gene is ttdA [C]

Identifier: 57234728

GI number: 57234728

Start: 429325

End: 430167

Strand: Direct

Name: ttdA [C]

Synonym: DET0453

Alternate gene names: 57234728

Gene position: 429325-430167 (Clockwise)

Preceding gene: 57234729

Following gene: 57234727

Centisome position: 29.21

GC content: 52.91

Gene sequence:

>843_bases
GTGCGGGAGATAGATTCATCCCAAATAAGTGCGGCTCTCTCGGAGCTTATTGTAAAAACCAGTACCAGCTTGGGTGATGA
CATTTTAACAGCTTTACATAAAGCATATGAAGCTGAAGTGTCTCCTGCCGGGCGGGATATACTTCTGAGTTTGCTTGAAA
ATGCCTGTATTGCCGGGGAGAAAAAAATACCCCTCTGTCAGGATACCGGTACGGCCATTGTCTTTGCCGAAGCAGGGCAG
GATGTGCATATAAATGGCAATCTTGTTGATGCTATAAATTTGGGTGTCAGGCAGGGGTACGAGCAGGCTTACCTCAGGAA
ATCTATTGTCTCCCAGCCGTTTTCCGAACGTGTAAATACCCAAGACAATACTCCGGCGGTTATTCATACTGAAATAGTTC
CCGGTGACCGTCTGAAGCTCAGTTTTATGGCTAAGGGAAGCGGAGCGGAGAATATGAGCCGCCTTTTCATGCTTAAGCCC
GGGGTGGGGCATGAAGGGGTGATAGAGGCGGTGCTGGAAACAGTGGAAAATGCCGGCGGCAGTCCCTGTCCGCCTATTAT
TATCGGGTTGGGGGTAGGGGCAACTGCCGAAAAGGCCATGTTTATGGCTAAAAAGGCTTTGCTTCGGCCGCTGGGCGTAT
CCAGCCCTGAGGCTGAGGTGGCGGCTCTGGAAGCCGAGGTGCTGAAACGGGTAAATGGCCTGGGTATAGGTCCGCTTGGC
TTAGGCGGTAGGGTGACTGCCCTGGGAGTGATGGCAGAAGCCGCACCCACCCATATTGCCAGTTTGCCGGTGGCGGTAAA
CCTGCAGTGCCATAGCGCCCGCCATGGTGAGGTGGTGCTGTGA

Upstream 100 bases:

>100_bases
GACCGAGCAGAACCGCGAAGAGGGTAAAGATGGTGCTTACAAAATGAAACAGGCCGGAGACCTGTTTGTAAAGGCCAGCG
AGTATTTAGAGGGTAAATAA

Downstream 100 bases:

>100_bases
TATCCGGTATAAAACTGAATTCCCCGTTTAACCCTGCTGAACTGGAAAAGCTGCAAGCCGGAGATAGGGTGCTGATATCC
GGTGTTATATATGCCGCCCG

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MREIDSSQISAALSELIVKTSTSLGDDILTALHKAYEAEVSPAGRDILLSLLENACIAGEKKIPLCQDTGTAIVFAEAGQ
DVHINGNLVDAINLGVRQGYEQAYLRKSIVSQPFSERVNTQDNTPAVIHTEIVPGDRLKLSFMAKGSGAENMSRLFMLKP
GVGHEGVIEAVLETVENAGGSPCPPIIIGLGVGATAEKAMFMAKKALLRPLGVSSPEAEVAALEAEVLKRVNGLGIGPLG
LGGRVTALGVMAEAAPTHIASLPVAVNLQCHSARHGEVVL

Sequences:

>Translated_280_residues
MREIDSSQISAALSELIVKTSTSLGDDILTALHKAYEAEVSPAGRDILLSLLENACIAGEKKIPLCQDTGTAIVFAEAGQ
DVHINGNLVDAINLGVRQGYEQAYLRKSIVSQPFSERVNTQDNTPAVIHTEIVPGDRLKLSFMAKGSGAENMSRLFMLKP
GVGHEGVIEAVLETVENAGGSPCPPIIIGLGVGATAEKAMFMAKKALLRPLGVSSPEAEVAALEAEVLKRVNGLGIGPLG
LGGRVTALGVMAEAAPTHIASLPVAVNLQCHSARHGEVVL
>Mature_280_residues
MREIDSSQISAALSELIVKTSTSLGDDILTALHKAYEAEVSPAGRDILLSLLENACIAGEKKIPLCQDTGTAIVFAEAGQ
DVHINGNLVDAINLGVRQGYEQAYLRKSIVSQPFSERVNTQDNTPAVIHTEIVPGDRLKLSFMAKGSGAENMSRLFMLKP
GVGHEGVIEAVLETVENAGGSPCPPIIIGLGVGATAEKAMFMAKKALLRPLGVSSPEAEVAALEAEVLKRVNGLGIGPLG
LGGRVTALGVMAEAAPTHIASLPVAVNLQCHSARHGEVVL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=288, Percent_Identity=31.5972222222222, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790564, Length=254, Percent_Identity=30.3149606299213, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787897, Length=254, Percent_Identity=31.1023622047244, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 29211; Mature: 29211

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIDSSQISAALSELIVKTSTSLGDDILTALHKAYEAEVSPAGRDILLSLLENACIAGE
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
KKIPLCQDTGTAIVFAEAGQDVHINGNLVDAINLGVRQGYEQAYLRKSIVSQPFSERVNT
CCCCEECCCCCEEEEEECCCEEEECCCEEHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCC
QDNTPAVIHTEIVPGDRLKLSFMAKGSGAENMSRLFMLKPGVGHEGVIEAVLETVENAGG
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
SPCPPIIIGLGVGATAEKAMFMAKKALLRPLGVSSPEAEVAALEAEVLKRVNGLGIGPLG
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
LGGRVTALGVMAEAAPTHIASLPVAVNLQCHSARHGEVVL
CCCHHHHHHHHHHHCCHHHHHCCEEEEEEECCCCCCCEEC
>Mature Secondary Structure
MREIDSSQISAALSELIVKTSTSLGDDILTALHKAYEAEVSPAGRDILLSLLENACIAGE
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
KKIPLCQDTGTAIVFAEAGQDVHINGNLVDAINLGVRQGYEQAYLRKSIVSQPFSERVNT
CCCCEECCCCCEEEEEECCCEEEECCCEEHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCC
QDNTPAVIHTEIVPGDRLKLSFMAKGSGAENMSRLFMLKPGVGHEGVIEAVLETVENAGG
CCCCCEEEEEEECCCCCEEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCC
SPCPPIIIGLGVGATAEKAMFMAKKALLRPLGVSSPEAEVAALEAEVLKRVNGLGIGPLG
CCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
LGGRVTALGVMAEAAPTHIASLPVAVNLQCHSARHGEVVL
CCCHHHHHHHHHHHCCHHHHHCCEEEEEEECCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]