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The map label for this gene is hycG [H]

Identifier: 57234359

GI number: 57234359

Start: 790726

End: 791193

Strand: Direct

Name: hycG [H]

Synonym: DET0862

Alternate gene names: 57234359

Gene position: 790726-791193 (Clockwise)

Preceding gene: 57234360

Following gene: 57234358

Centisome position: 53.8

GC content: 49.79

Gene sequence:

>468_bases
GTGGATTTTGTTACTAAATCTCAAATAAAATCACCCTGGCTGCTCCATTTTGACTGCGGCAGCTGTAACGGCTGTGATAT
TGAAATACTGGCCTGTCTTACCCCCCTTTATGATGTTGAACGCTTCGGCATTGTTAACATGGGTAACCCCAAACACTCGG
ATGTACTTCTGGTAACCGGCCCGGCCAATAAGCGTAATTACCGTGTTTTGCAAAACTTGTACCAGCAAATGCCTGACCCG
AAGGTAGTAATAGTTATCGGCACCTGCGGCTGCAGCGGCGGTGTTTTCCATAACTGCCCGAATATACTGGGCGGGGTAGA
CAAGGTAATACCGGTGGACGTATATGTGCCCGGTTGTGCCGCCAGACCGGAGGCTATTATAGACGGCGTGGTTATGGGGC
TGGGCAAGCTGGCTGAGAAAAAAGCCAAGGCCAAAACTGAAGCCAAACGTGAGGAACAGCATGTGTAA

Upstream 100 bases:

>100_bases
CCGCCTTACCTGGTCTTCCATGCTCAAAATCTCCTGGATGTTCGGTTTGGGTCTGGCTTTGGTTAATCTTATCGGACTTT
CAGCACTGGGAGGGGTTTAA

Downstream 100 bases:

>100_bases
TTGTGAAACCAAAGCACCTGAGGTTATAGACCTGTCAAAGCTGGATAATATCCTGGACGGTTACCGTGATAAAGCTGATA
TGCTTATTCAGGTACTCCTT

Product: hydrogenase, group 4, EchC subunit, putative

Products: CO2; H2; oxidized ferredoxin + [C]

Alternate protein names: FHL subunit 7; Hydrogenase-3 component G [H]

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MDFVTKSQIKSPWLLHFDCGSCNGCDIEILACLTPLYDVERFGIVNMGNPKHSDVLLVTGPANKRNYRVLQNLYQQMPDP
KVVIVIGTCGCSGGVFHNCPNILGGVDKVIPVDVYVPGCAARPEAIIDGVVMGLGKLAEKKAKAKTEAKREEQHV

Sequences:

>Translated_155_residues
MDFVTKSQIKSPWLLHFDCGSCNGCDIEILACLTPLYDVERFGIVNMGNPKHSDVLLVTGPANKRNYRVLQNLYQQMPDP
KVVIVIGTCGCSGGVFHNCPNILGGVDKVIPVDVYVPGCAARPEAIIDGVVMGLGKLAEKKAKAKTEAKREEQHV
>Mature_155_residues
MDFVTKSQIKSPWLLHFDCGSCNGCDIEILACLTPLYDVERFGIVNMGNPKHSDVLLVTGPANKRNYRVLQNLYQQMPDP
KVVIVIGTCGCSGGVFHNCPNILGGVDKVIPVDVYVPGCAARPEAIIDGVVMGLGKLAEKKAKAKTEAKREEQHV

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG3260

COG function: function code C; Ni,Fe-hydrogenase III small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI187281616, Length=140, Percent_Identity=32.8571428571429, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789074, Length=144, Percent_Identity=45.8333333333333, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1788834, Length=131, Percent_Identity=41.2213740458015, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1788624, Length=132, Percent_Identity=39.3939393939394, Blast_Score=95, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17509685, Length=148, Percent_Identity=37.1621621621622, Blast_Score=107, Evalue=3e-24,
Organism=Drosophila melanogaster, GI18859983, Length=145, Percent_Identity=35.1724137931034, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24642371, Length=145, Percent_Identity=35.1724137931034, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24651058, Length=145, Percent_Identity=32.4137931034483, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: NA

Molecular weight: Translated: 16838; Mature: 16838

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFVTKSQIKSPWLLHFDCGSCNGCDIEILACLTPLYDVERFGIVNMGNPKHSDVLLVTG
CCCCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEC
PANKRNYRVLQNLYQQMPDPKVVIVIGTCGCSGGVFHNCPNILGGVDKVIPVDVYVPGCA
CCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCC
ARPEAIIDGVVMGLGKLAEKKAKAKTEAKREEQHV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFVTKSQIKSPWLLHFDCGSCNGCDIEILACLTPLYDVERFGIVNMGNPKHSDVLLVTG
CCCCCCCCCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCEEECCCCCCCCEEEEEC
PANKRNYRVLQNLYQQMPDPKVVIVIGTCGCSGGVFHNCPNILGGVDKVIPVDVYVPGCA
CCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCC
ARPEAIIDGVVMGLGKLAEKKAKAKTEAKREEQHV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; Proton; reduced ferredoxin [C]

Specific reaction: formate = CO2 + H2 Proton + reduced ferredoxin = H2 + oxidized ferredoxin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]