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The map label for this gene is nuoG [H]

Identifier: 57234356

GI number: 57234356

Start: 793607

End: 794200

Strand: Direct

Name: nuoG [H]

Synonym: DET0865

Alternate gene names: 57234356

Gene position: 793607-794200 (Clockwise)

Preceding gene: 57234357

Following gene: 57234355

Centisome position: 54.0

GC content: 52.02

Gene sequence:

>594_bases
ATGGAAGAAATCAAGCTTACCATAGATGGCAGGGAAGTTACTGCCCAAAGCGGGCAAACTGTTTTTCAGGCAGCGGCGGC
AGCCGGTATTCATATACCCGCGCTTTGCTTCCATGAACAGCTTGAACCATATGGCGGCTGCCGTGTCTGCAGCGTGGAGG
TAGTAACAGGCTCACGCTCCAAGGTGGTAGCTTCGTGTGTTTATCCGGCGTCAAACGGCCTGGTAGTAAATACCAATACC
GAAAAAATACGCCATATCCGCAAGGTACTTATAGAGCTGCTGCTCACCAAAGCCCCCGCTTCAAAACCCATACGAGACCT
GGCAGAAGAATACGGGGCGGATGCCGCCCGCTTCAGCCATGATGCCTCTTTCTGCGTGCTCTGCGGTTTATGTGTGCGCT
ACTGTACCGAGGTTAAAAAAGCCAACGCTTTGTGCTTTATCAGCCGGGGTACTCAGCGGGAGGTAACCTTCGTACCGGAG
ATAGCCAGCCGGGAATGCGAAAAATGCCAGCAGTGCTTTGATATCTGCCCCACCAATTTTATCCGGGCTAATTTTGAAAT
GGCCAAAGCTCTCACTTTCGGGACTGAGGAATAG

Upstream 100 bases:

>100_bases
CCTGCCCGGCCAAATTTTATGCGGTCAGGAAAATATCCGGCATACCTATACCGGACAACGTACCGTCTGAACCTATTCCT
TTAAACCGGAAGGCAGAATA

Downstream 100 bases:

>100_bases
TTATGTTAGAAAATGCTGAATATATAAAAGCCGAGGAACTGCTTGACCAGACCCAGAAGCTTTATGACGAGGGGGCGATA
TTCTGTACCGCCTCCTGCGT

Product: hydrogenase subunit HymC, putative

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MEEIKLTIDGREVTAQSGQTVFQAAAAAGIHIPALCFHEQLEPYGGCRVCSVEVVTGSRSKVVASCVYPASNGLVVNTNT
EKIRHIRKVLIELLLTKAPASKPIRDLAEEYGADAARFSHDASFCVLCGLCVRYCTEVKKANALCFISRGTQREVTFVPE
IASRECEKCQQCFDICPTNFIRANFEMAKALTFGTEE

Sequences:

>Translated_197_residues
MEEIKLTIDGREVTAQSGQTVFQAAAAAGIHIPALCFHEQLEPYGGCRVCSVEVVTGSRSKVVASCVYPASNGLVVNTNT
EKIRHIRKVLIELLLTKAPASKPIRDLAEEYGADAARFSHDASFCVLCGLCVRYCTEVKKANALCFISRGTQREVTFVPE
IASRECEKCQQCFDICPTNFIRANFEMAKALTFGTEE
>Mature_197_residues
MEEIKLTIDGREVTAQSGQTVFQAAAAAGIHIPALCFHEQLEPYGGCRVCSVEVVTGSRSKVVASCVYPASNGLVVNTNT
EKIRHIRKVLIELLLTKAPASKPIRDLAEEYGADAARFSHDASFCVLCGLCVRYCTEVKKANALCFISRGTQREVTFVPE
IASRECEKCQQCFDICPTNFIRANFEMAKALTFGTEE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=200, Percent_Identity=30.5, Blast_Score=94, Evalue=6e-20,
Organism=Escherichia coli, GI145693161, Length=202, Percent_Identity=26.2376237623762, Blast_Score=81, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193209088, Length=205, Percent_Identity=29.2682926829268, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32566231, Length=205, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17565758, Length=205, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24640559, Length=207, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640557, Length=207, Percent_Identity=30.4347826086957, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 21589; Mature: 21589

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
6.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEIKLTIDGREVTAQSGQTVFQAAAAAGIHIPALCFHEQLEPYGGCRVCSVEVVTGSRS
CCCEEEEECCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCH
KVVASCVYPASNGLVVNTNTEKIRHIRKVLIELLLTKAPASKPIRDLAEEYGADAARFSH
HEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCC
DASFCVLCGLCVRYCTEVKKANALCFISRGTQREVTFVPEIASRECEKCQQCFDICPTNF
CCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCHH
IRANFEMAKALTFGTEE
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEEIKLTIDGREVTAQSGQTVFQAAAAAGIHIPALCFHEQLEPYGGCRVCSVEVVTGSRS
CCCEEEEECCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCCH
KVVASCVYPASNGLVVNTNTEKIRHIRKVLIELLLTKAPASKPIRDLAEEYGADAARFSH
HEEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHCC
DASFCVLCGLCVRYCTEVKKANALCFISRGTQREVTFVPEIASRECEKCQQCFDICPTNF
CCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHCCCHH
IRANFEMAKALTFGTEE
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA