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The map label for this gene is arsB [H]

Identifier: 57234339

GI number: 57234339

Start: 833734

End: 835008

Strand: Direct

Name: arsB [H]

Synonym: DET0908

Alternate gene names: 57234339

Gene position: 833734-835008 (Clockwise)

Preceding gene: 57234342

Following gene: 57234330

Centisome position: 56.73

GC content: 45.73

Gene sequence:

>1275_bases
ATGCTCTGGTTGGCTTTATCTATATTCGTTACCACCATTCTGTTAGTGGTATTTAAACCTCGGCCGTTTAACGAAGCCGG
GGCTATTTGTTTTGGGGTCTTTTTAATGCTTGTGCTGGGGCTGATTCCCCTGTCAAGTATCGGGCAGACTTTAGCTACCA
ACCTGAACATTTTATTTTTCTTCCTCGGGCTCATGCTGGTTAGTTATTTCGCAGAGTTGTCCGGTTTTTTTGATTCGGCC
GCTAACTTGGCTCTGAAGCTTTCAAACGGCAGCTCTTGGCGGCTGCTGGGGCTGGTTTTTGCACTGGGTATTGTTATCAC
TATGTTTATGTCAAATGATGCCACTGCCCTGCTCTTAACCCCGGTAATTTTTATGCTTGTCCAGCGCTACGGGCTGAAGC
CTTTGCCATATGTATTTGCCTGCGCTTTTGTGGCTAACGCAGCCTCATTTATCTTCCCTTTTTCCAATCCGGTAAATCTA
CTGGCGGTAGATAAATTCGGCCTTAGCCTAAGTGAATATCTGGGATTTATGTTAATCCCAGCCCTGCTTGCTATTACCAT
TATGATAGTCATATTTTACTTTATTTTCCGCCGTGACCTTAAAGCGGGGTTTTCACTGGTAACGGCTAAGGCGGTTGTAG
CAAATAATTTTTCTCGCTCGGTCAGGCTGGCATTGGTTTTTCTGGCAATAGGCTGCCTTTTAACTTCGTTTATGGGGTGG
CCACTGGCAATCCCTCTTATGCTGACTGCATTTATTCTGATGGGCATAACCCTATTCTATAAAAAAATGGATTTCGGGCA
TCTTCGGCAGTCTGTTTCATGGTCAATACTGCCCTTTGTACTGGGATTGGCTTTTATGGTAAACGGATTGGAAAATGCCG
GAATTACTTCGGCACTGGGGAATTGGCTTTCCGGCACTATGGCCGGCGACAACCAGCTGGAAACAGGGCTAATTACCTCT
TTCGGGACAGCTATCGGTTCTAACCTTATAAATAACTGGCCGATGATGATGGTCTCAGTATCCAGTTTATCCGCCATAAC
TGATATCAGCGGCGGCAATGCATGGCTGGTGTATCAGGCTATTTTGGGCGCAGATTTGGGGCCTAATCTGCTGATAATGG
GTTCTCTGTCCACCATGCTCTGGCTTATGCTCCTGCGGAAACGGGGGCTGATAATAAAGCCCCTGGATTATACCAGACTG
GGTCTTATTATAACCCCGCCGTCTCTGTTGGTATCTACATTTGCCATATTTCAATTAGGAAAACTGAGTAATTAA

Upstream 100 bases:

>100_bases
GCTGCCAAGCCCGTTAAAAAGTAACTGGTAATCAACTGATGGTAAAGGGCAGGAGAATCTCTCTCGCATCAAGGGTGATT
CTCCTGCATTATTTTTGAAT

Downstream 100 bases:

>100_bases
GATGAAAAATATCACTCGCCAGAGTTTAGATAACAGCATCAAAGACGGAGCGGCCTATTCAGCCATGCTGGGGCTGACCC
AGGATTATGTAACACCTTTT

Product: arsenical pump membrane protein, putative

Products: ADP; phosphate; arsenite [Periplasm] [C]

Alternate protein names: Arsenic efflux pump protein [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MLWLALSIFVTTILLVVFKPRPFNEAGAICFGVFLMLVLGLIPLSSIGQTLATNLNILFFFLGLMLVSYFAELSGFFDSA
ANLALKLSNGSSWRLLGLVFALGIVITMFMSNDATALLLTPVIFMLVQRYGLKPLPYVFACAFVANAASFIFPFSNPVNL
LAVDKFGLSLSEYLGFMLIPALLAITIMIVIFYFIFRRDLKAGFSLVTAKAVVANNFSRSVRLALVFLAIGCLLTSFMGW
PLAIPLMLTAFILMGITLFYKKMDFGHLRQSVSWSILPFVLGLAFMVNGLENAGITSALGNWLSGTMAGDNQLETGLITS
FGTAIGSNLINNWPMMMVSVSSLSAITDISGGNAWLVYQAILGADLGPNLLIMGSLSTMLWLMLLRKRGLIIKPLDYTRL
GLIITPPSLLVSTFAIFQLGKLSN

Sequences:

>Translated_424_residues
MLWLALSIFVTTILLVVFKPRPFNEAGAICFGVFLMLVLGLIPLSSIGQTLATNLNILFFFLGLMLVSYFAELSGFFDSA
ANLALKLSNGSSWRLLGLVFALGIVITMFMSNDATALLLTPVIFMLVQRYGLKPLPYVFACAFVANAASFIFPFSNPVNL
LAVDKFGLSLSEYLGFMLIPALLAITIMIVIFYFIFRRDLKAGFSLVTAKAVVANNFSRSVRLALVFLAIGCLLTSFMGW
PLAIPLMLTAFILMGITLFYKKMDFGHLRQSVSWSILPFVLGLAFMVNGLENAGITSALGNWLSGTMAGDNQLETGLITS
FGTAIGSNLINNWPMMMVSVSSLSAITDISGGNAWLVYQAILGADLGPNLLIMGSLSTMLWLMLLRKRGLIIKPLDYTRL
GLIITPPSLLVSTFAIFQLGKLSN
>Mature_424_residues
MLWLALSIFVTTILLVVFKPRPFNEAGAICFGVFLMLVLGLIPLSSIGQTLATNLNILFFFLGLMLVSYFAELSGFFDSA
ANLALKLSNGSSWRLLGLVFALGIVITMFMSNDATALLLTPVIFMLVQRYGLKPLPYVFACAFVANAASFIFPFSNPVNL
LAVDKFGLSLSEYLGFMLIPALLAITIMIVIFYFIFRRDLKAGFSLVTAKAVVANNFSRSVRLALVFLAIGCLLTSFMGW
PLAIPLMLTAFILMGITLFYKKMDFGHLRQSVSWSILPFVLGLAFMVNGLENAGITSALGNWLSGTMAGDNQLETGLITS
FGTAIGSNLINNWPMMMVSVSSLSAITDISGGNAWLVYQAILGADLGPNLLIMGSLSTMLWLMLLRKRGLIIKPLDYTRL
GLIITPPSLLVSTFAIFQLGKLSN

Specific function: Involved in arsenical resistance. Thought to form the channel of an arsenite pump [H]

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsB family [H]

Homologues:

Organism=Escherichia coli, GI87082277, Length=423, Percent_Identity=30.2600472813239, Blast_Score=155, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802 [H]

Pfam domain/function: PF02040 ArsB [H]

EC number: NA

Molecular weight: Translated: 46113; Mature: 46113

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWLALSIFVTTILLVVFKPRPFNEAGAICFGVFLMLVLGLIPLSSIGQTLATNLNILFF
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
FLGLMLVSYFAELSGFFDSAANLALKLSNGSSWRLLGLVFALGIVITMFMSNDATALLLT
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PVIFMLVQRYGLKPLPYVFACAFVANAASFIFPFSNPVNLLAVDKFGLSLSEYLGFMLIP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCEEEEEHHCCCHHHHHHHHHHH
ALLAITIMIVIFYFIFRRDLKAGFSLVTAKAVVANNFSRSVRLALVFLAIGCLLTSFMGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
PLAIPLMLTAFILMGITLFYKKMDFGHLRQSVSWSILPFVLGLAFMVNGLENAGITSALG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
NWLSGTMAGDNQLETGLITSFGTAIGSNLINNWPMMMVSVSSLSAITDISGGNAWLVYQA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEHHHHH
ILGADLGPNLLIMGSLSTMLWLMLLRKRGLIIKPLDYTRLGLIITPPSLLVSTFAIFQLG
HHCCCCCCCEEEECCHHHHHHHHHHHHCCCEEECCCCCCEEEEECCHHHHHHHHHHHHHH
KLSN
CCCC
>Mature Secondary Structure
MLWLALSIFVTTILLVVFKPRPFNEAGAICFGVFLMLVLGLIPLSSIGQTLATNLNILFF
CHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
FLGLMLVSYFAELSGFFDSAANLALKLSNGSSWRLLGLVFALGIVITMFMSNDATALLLT
HHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PVIFMLVQRYGLKPLPYVFACAFVANAASFIFPFSNPVNLLAVDKFGLSLSEYLGFMLIP
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCCCCEEEEEHHCCCHHHHHHHHHHH
ALLAITIMIVIFYFIFRRDLKAGFSLVTAKAVVANNFSRSVRLALVFLAIGCLLTSFMGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCC
PLAIPLMLTAFILMGITLFYKKMDFGHLRQSVSWSILPFVLGLAFMVNGLENAGITSALG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
NWLSGTMAGDNQLETGLITSFGTAIGSNLINNWPMMMVSVSSLSAITDISGGNAWLVYQA
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEHHHHH
ILGADLGPNLLIMGSLSTMLWLMLLRKRGLIIKPLDYTRLGLIITPPSLLVSTFAIFQLG
HHCCCCCCCEEEECCHHHHHHHHHHHHCCCEEECCCCCCEEEEECCHHHHHHHHHHHHHH
KLSN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arsenite [Cytoplasm]; H2O [C]

Specific reaction: ATP + arsenite [Cytoplasm] + H2O = ADP + phosphate + arsenite [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA