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The map label for this gene is nuoA [H]

Identifier: 57234307

GI number: 57234307

Start: 845625

End: 845996

Strand: Direct

Name: nuoA [H]

Synonym: DET0923

Alternate gene names: 57234307

Gene position: 845625-845996 (Clockwise)

Preceding gene: 57234308

Following gene: 57234306

Centisome position: 57.54

GC content: 46.24

Gene sequence:

>372_bases
ATGCTGACTGATTACGGCTATATTGCACTATTCCTTGTCGCTGCAATACTCTTTACCGCCATAGTACTAGGCCTACCGGT
TCTCCTTCGTATAATCGGCATCGTGCCTAACAAACCTGACAAAGTCAAAAATGCCACCTATGAATGCGGTGTGGAAACCC
AAGGCCGCACCTGGGTTCAGTTTAATTTCCGTTATTATTATTATGCCCTGCTGCTGATTGCTTTTGATGTACTGCTGGTC
TTTCTTTTCCCCTGGGCAACCCAGATAGGTTCGCTCGGGTTTTATGCTTTTGGAATAGTGCTTGCCTTTCTGATAATAGT
CATGGTGGGCTACCTGTATGCCTGGAAGAAGGGGGCTTTGGAATGGAACTAG

Upstream 100 bases:

>100_bases
CTTTAAGTTACTATTTTATAATACCATTACATCATATTTAAGCTTTACTCTTCAAGGGGACTAATGCTATAGTAGTAAAA
AGTATTTCAGGGGAGGAATT

Downstream 100 bases:

>100_bases
ATTCGGGAAAACCACTGAGCCTGCTTACGCTGGATGAAATTGACCAGCATGAAGGCGGCATAATTCAAAGCTTCCGCACC
GGTCATACCACGCCTTACCC

Product: proton-translocating NADH-quinone oxidoreductase, A subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MLTDYGYIALFLVAAILFTAIVLGLPVLLRIIGIVPNKPDKVKNATYECGVETQGRTWVQFNFRYYYYALLLIAFDVLLV
FLFPWATQIGSLGFYAFGIVLAFLIIVMVGYLYAWKKGALEWN

Sequences:

>Translated_123_residues
MLTDYGYIALFLVAAILFTAIVLGLPVLLRIIGIVPNKPDKVKNATYECGVETQGRTWVQFNFRYYYYALLLIAFDVLLV
FLFPWATQIGSLGFYAFGIVLAFLIIVMVGYLYAWKKGALEWN
>Mature_123_residues
MLTDYGYIALFLVAAILFTAIVLGLPVLLRIIGIVPNKPDKVKNATYECGVETQGRTWVQFNFRYYYYALLLIAFDVLLV
FLFPWATQIGSLGFYAFGIVLAFLIIVMVGYLYAWKKGALEWN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 14005; Mature: 14005

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDYGYIALFLVAAILFTAIVLGLPVLLRIIGIVPNKPDKVKNATYECGVETQGRTWVQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCEEEE
FNFRYYYYALLLIAFDVLLVFLFPWATQIGSLGFYAFGIVLAFLIIVMVGYLYAWKKGAL
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EWN
CCC
>Mature Secondary Structure
MLTDYGYIALFLVAAILFTAIVLGLPVLLRIIGIVPNKPDKVKNATYECGVETQGRTWVQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCEEEE
FNFRYYYYALLLIAFDVLLVFLFPWATQIGSLGFYAFGIVLAFLIIVMVGYLYAWKKGAL
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EWN
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA