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The map label for this gene is nuoC2 [H]

Identifier: 57234305

GI number: 57234305

Start: 846594

End: 847040

Strand: Direct

Name: nuoC2 [H]

Synonym: DET0925

Alternate gene names: 57234305

Gene position: 846594-847040 (Clockwise)

Preceding gene: 57234306

Following gene: 57234304

Centisome position: 57.6

GC content: 45.41

Gene sequence:

>447_bases
ATGACCGCCGTACTTGATTACCAACAACTGAAGGCTGATTTATCTAAAGAACTGCCCGGGATTGAAATCCAGGCGGAAAG
TTCTTTCCTGCTGGCTTTGCCTGAGGATATACACCATGTGTGCCAATATCTGGTTTCCCGGCCGTTGCAAATGGACTACC
TGACCAACCTTACCGCGGCTGACTATCCTGAATACATAGAAATAATTTTCCATTTGAATTCAATTGTGAACAATACCGCC
ATGACACTTAAAACCCGCCTGACTGACAAGACTAACCCCAAAATGGCTTCGGTAGTGGATATCTGGCGGGGAGCAGAACT
GCAGGAACGTGAAATATATGACCTTTTCGGAGTGGTTTTTGAAAACCATATAGGCCTGAAACGCATTTTCCTGTGGGAGG
GCTTTGAAGGTTATCCTTTGCGCAAGGACTTTGCAAATGGCCATTAA

Upstream 100 bases:

>100_bases
TATGTACCCGGCTGCCCTCCCCGTCCGGAAGCCCTTTTAAGGGCTATCATGGATATCCACGAAAAAATAGATAAAACCCG
CATTATAAAGAGATAGATTC

Downstream 100 bases:

>100_bases
AACTGAAAGCTTTATTTTAAATATAGGCCCCCAGCACCCCAGCACCCACGGGGTGTTCCGTCTGCGGCTGATTCTGGACG
GTGAGGTTATTACCGACCTG

Product: proton-translocating NADH-quinone oxidoreductase, C subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C 2; NDH-1 subunit C 2 [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MTAVLDYQQLKADLSKELPGIEIQAESSFLLALPEDIHHVCQYLVSRPLQMDYLTNLTAADYPEYIEIIFHLNSIVNNTA
MTLKTRLTDKTNPKMASVVDIWRGAELQEREIYDLFGVVFENHIGLKRIFLWEGFEGYPLRKDFANGH

Sequences:

>Translated_148_residues
MTAVLDYQQLKADLSKELPGIEIQAESSFLLALPEDIHHVCQYLVSRPLQMDYLTNLTAADYPEYIEIIFHLNSIVNNTA
MTLKTRLTDKTNPKMASVVDIWRGAELQEREIYDLFGVVFENHIGLKRIFLWEGFEGYPLRKDFANGH
>Mature_147_residues
TAVLDYQQLKADLSKELPGIEIQAESSFLLALPEDIHHVCQYLVSRPLQMDYLTNLTAADYPEYIEIIFHLNSIVNNTAM
TLKTRLTDKTNPKMASVVDIWRGAELQEREIYDLFGVVFENHIGLKRIFLWEGFEGYPLRKDFANGH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=98, Percent_Identity=43.8775510204082, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563621, Length=119, Percent_Identity=36.9747899159664, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71990788, Length=119, Percent_Identity=36.9747899159664, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24656494, Length=119, Percent_Identity=35.2941176470588, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17076; Mature: 16945

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVLDYQQLKADLSKELPGIEIQAESSFLLALPEDIHHVCQYLVSRPLQMDYLTNLTAA
CCCCCCHHHHHHHHHHCCCCEEEEECCCEEEECCHHHHHHHHHHHHCCCCHHHHHCCCCC
DYPEYIEIIFHLNSIVNNTAMTLKTRLTDKTNPKMASVVDIWRGAELQEREIYDLFGVVF
CCHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
ENHIGLKRIFLWEGFEGYPLRKDFANGH
HCCCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TAVLDYQQLKADLSKELPGIEIQAESSFLLALPEDIHHVCQYLVSRPLQMDYLTNLTAA
CCCCCHHHHHHHHHHCCCCEEEEECCCEEEECCHHHHHHHHHHHHCCCCHHHHHCCCCC
DYPEYIEIIFHLNSIVNNTAMTLKTRLTDKTNPKMASVVDIWRGAELQEREIYDLFGVVF
CCHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
ENHIGLKRIFLWEGFEGYPLRKDFANGH
HCCCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA