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The map label for this gene is argJ

Identifier: 57233978

GI number: 57233978

Start: 1142595

End: 1143812

Strand: Direct

Name: argJ

Synonym: DET1256

Alternate gene names: 57233978

Gene position: 1142595-1143812 (Clockwise)

Preceding gene: 57233979

Following gene: 57233977

Centisome position: 77.74

GC content: 51.56

Gene sequence:

>1218_bases
ATGAAAAGCAGTATAGATATTTTGCCTGACGGCAGCATTACCACACCCAAAGGTTTCAAAACCGGCGCTATTTATGCGGG
TATCAAAAAGAAGTCCAAGAACAATCTGGATTTAACTATTTTGTACTCGGATACGCCCTGCGTGGCCGCAGGCATATTCA
CTACCAACAAATTCCGGGCTGCCCCGGTCTATATTTCAGAACACAATCTGGGTTTCCCGGATAACCGGGCTATTGTAGTC
AACAGCGGCTGTGCCAATGCCGGAACAGGTGAAGCCGGTATGGCAGATGCCATTGAGATGGTAAAGACTACGGCTGAAAC
CCTGAATATGCAGCCCAAAGATGTGCTGATAGCGTCTACCGGGGTTATCGGCCACCGCCTGCCCATGGATAAAATCAAAG
AGAGTATCCGCCTGATAGGTCTTTCCCAGCGCAACGGGCATGATTTTGCCCGGGCAATAATGACTACCGACACCCGCAGC
AAGGAGATTGCAGTCCGGGTAAATATAGAAGGTTTCCAGTTTTACATAGCCGGAGCGGCCAAAGGGGCGGGAATGATTCA
CCCCAATATGGCTACCCTGCTGGGTTTTATAACCACAGATGCCTCCGTAAGCAAGGATTTTTTGCAGTTTGCCCTTAAAG
AAGCGGCGGATATCAGCTTCAATATGATAACGGTAGACGGTGATACCTCTACTAATGACAGCCTCTTCATGCTGGCAAAC
GGCCAAGCCGAAAACCCCACCTTTGCCGGAGATACCGAATATTCGCTGGTATTCCAGCAGGCACTTAACATTGTCTGCCA
GTCTCTGGCTAAGAGTGTTGCCCGGGACGGTGAAGGCGCTAAACGGCTGATTGAAATACAGGTGGAAGGCGCAGCCAGCC
TGGAAGACGCCAGACTGATTGCCCGCGCGGTAGCCGGCTCACCGCTGGTGAAGACCGCTGTCCACGGGGCTGACCCCAAC
TGGGGACGGATACTGGCGGCCGCCGGACGGTCCGGGGCTGATTTTGATATAGAACGGGTGGACTTGTACCTTGGCGAAAG
CCGGGTACTCCAAAAAGGCCAGCGCACAGGTGCAGACGAAAAAGAACTGTCTTCGTGGCTTAAACAGGTAGAAGTTATTA
TAAAACTGAACCTGAACCTGGGCGAAGGCAAATCTACCGCCTGGGGTTGTGACCTTTCAGCCGAATACGTAAAAATAAAC
GCGGACTACACCACTTAA

Upstream 100 bases:

>100_bases
GGGGGACTTAGAAACCCTGCTGACAGGCGGGTAAATTTCACCTTGTCCAGGTGCCTTTTTAAATTGCCCTCCGGCTTGGG
AAGTGGTATATTCTAGTGCT

Downstream 100 bases:

>100_bases
ACTGAAATGAATGTATCCCAAGTGAGTAACCATATAGTTGTAATAAAGCTGGGGGGTTCAGTCCTTAGTTCCAAGGACAC
CTCCCTGAAAGATATTGCCG

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MKSSIDILPDGSITTPKGFKTGAIYAGIKKKSKNNLDLTILYSDTPCVAAGIFTTNKFRAAPVYISEHNLGFPDNRAIVV
NSGCANAGTGEAGMADAIEMVKTTAETLNMQPKDVLIASTGVIGHRLPMDKIKESIRLIGLSQRNGHDFARAIMTTDTRS
KEIAVRVNIEGFQFYIAGAAKGAGMIHPNMATLLGFITTDASVSKDFLQFALKEAADISFNMITVDGDTSTNDSLFMLAN
GQAENPTFAGDTEYSLVFQQALNIVCQSLAKSVARDGEGAKRLIEIQVEGAASLEDARLIARAVAGSPLVKTAVHGADPN
WGRILAAAGRSGADFDIERVDLYLGESRVLQKGQRTGADEKELSSWLKQVEVIIKLNLNLGEGKSTAWGCDLSAEYVKIN
ADYTT

Sequences:

>Translated_405_residues
MKSSIDILPDGSITTPKGFKTGAIYAGIKKKSKNNLDLTILYSDTPCVAAGIFTTNKFRAAPVYISEHNLGFPDNRAIVV
NSGCANAGTGEAGMADAIEMVKTTAETLNMQPKDVLIASTGVIGHRLPMDKIKESIRLIGLSQRNGHDFARAIMTTDTRS
KEIAVRVNIEGFQFYIAGAAKGAGMIHPNMATLLGFITTDASVSKDFLQFALKEAADISFNMITVDGDTSTNDSLFMLAN
GQAENPTFAGDTEYSLVFQQALNIVCQSLAKSVARDGEGAKRLIEIQVEGAASLEDARLIARAVAGSPLVKTAVHGADPN
WGRILAAAGRSGADFDIERVDLYLGESRVLQKGQRTGADEKELSSWLKQVEVIIKLNLNLGEGKSTAWGCDLSAEYVKIN
ADYTT
>Mature_405_residues
MKSSIDILPDGSITTPKGFKTGAIYAGIKKKSKNNLDLTILYSDTPCVAAGIFTTNKFRAAPVYISEHNLGFPDNRAIVV
NSGCANAGTGEAGMADAIEMVKTTAETLNMQPKDVLIASTGVIGHRLPMDKIKESIRLIGLSQRNGHDFARAIMTTDTRS
KEIAVRVNIEGFQFYIAGAAKGAGMIHPNMATLLGFITTDASVSKDFLQFALKEAADISFNMITVDGDTSTNDSLFMLAN
GQAENPTFAGDTEYSLVFQQALNIVCQSLAKSVARDGEGAKRLIEIQVEGAASLEDARLIARAVAGSPLVKTAVHGADPN
WGRILAAAGRSGADFDIERVDLYLGESRVLQKGQRTGADEKELSSWLKQVEVIIKLNLNLGEGKSTAWGCDLSAEYVKIN
ADYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=414, Percent_Identity=40.0966183574879, Blast_Score=266, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_DEHE1 (Q3Z731)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181968.1
- ProteinModelPortal:   Q3Z731
- SMR:   Q3Z731
- STRING:   Q3Z731
- MEROPS:   T05.001
- GeneID:   3229443
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET1256
- NMPDR:   fig|243164.3.peg.1204
- TIGR:   DET1256
- eggNOG:   COG1364
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- PhylomeDB:   Q3Z731
- ProtClustDB:   PRK05388
- BioCyc:   DETH243164:DET_1256-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 43306; Mature: 43306

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSIDILPDGSITTPKGFKTGAIYAGIKKKSKNNLDLTILYSDTPCVAAGIFTTNKFRA
CCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCEEE
APVYISEHNLGFPDNRAIVVNSGCANAGTGEAGMADAIEMVKTTAETLNMQPKDVLIAST
CEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
GVIGHRLPMDKIKESIRLIGLSQRNGHDFARAIMTTDTRSKEIAVRVNIEGFQFYIAGAA
CCCCCCCCHHHHHHHHEEEEECCCCCCHHHHHHHCCCCCCCEEEEEEEECCEEEEEEECC
KGAGMIHPNMATLLGFITTDASVSKDFLQFALKEAADISFNMITVDGDTSTNDSLFMLAN
CCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEC
GQAENPTFAGDTEYSLVFQQALNIVCQSLAKSVARDGEGAKRLIEIQVEGAASLEDARLI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHH
ARAVAGSPLVKTAVHGADPNWGRILAAAGRSGADFDIERVDLYLGESRVLQKGQRTGADE
HHHHCCCCHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCH
KELSSWLKQVEVIIKLNLNLGEGKSTAWGCDLSAEYVKINADYTT
HHHHHHHHHEEEEEEEECCCCCCCCCEECCCCCEEEEEEEECCCC
>Mature Secondary Structure
MKSSIDILPDGSITTPKGFKTGAIYAGIKKKSKNNLDLTILYSDTPCVAAGIFTTNKFRA
CCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCEEE
APVYISEHNLGFPDNRAIVVNSGCANAGTGEAGMADAIEMVKTTAETLNMQPKDVLIAST
CEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
GVIGHRLPMDKIKESIRLIGLSQRNGHDFARAIMTTDTRSKEIAVRVNIEGFQFYIAGAA
CCCCCCCCHHHHHHHHEEEEECCCCCCHHHHHHHCCCCCCCEEEEEEEECCEEEEEEECC
KGAGMIHPNMATLLGFITTDASVSKDFLQFALKEAADISFNMITVDGDTSTNDSLFMLAN
CCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEEC
GQAENPTFAGDTEYSLVFQQALNIVCQSLAKSVARDGEGAKRLIEIQVEGAASLEDARLI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHH
ARAVAGSPLVKTAVHGADPNWGRILAAAGRSGADFDIERVDLYLGESRVLQKGQRTGADE
HHHHCCCCHHHHHCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHCCCCH
KELSSWLKQVEVIIKLNLNLGEGKSTAWGCDLSAEYVKINADYTT
HHHHHHHHHEEEEEEEECCCCCCCCCEECCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA