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The map label for this gene is argS

Identifier: 57233947

GI number: 57233947

Start: 1158377

End: 1160047

Strand: Direct

Name: argS

Synonym: DET1270

Alternate gene names: 57233947

Gene position: 1158377-1160047 (Clockwise)

Preceding gene: 57233948

Following gene: 57233945

Centisome position: 78.82

GC content: 51.59

Gene sequence:

>1671_bases
TTGAACAGTATCTTAGCTATCAAAAATATTATTATAGAGTCTCTCAGCCAGGCTCTGGAAAAAGCCCGTCAGGAAGGGCA
GATTCCGGCGCTCAGCGTGGATATAAGCATAGAGCACCCCCAAAAAACCAATTATGGTGACTATGCCACCAGCCTGCCTT
TGCGGCTAGCCAAGGCTACCGGCAAACGCCCCATGGAGCTGGCTGAAATACTGGCCGGCTATATTGAACCCGGTGAAGGC
ATTGCCAAAGTAAGCGTAGCCCCTCCCGGCTTTATAAATTTCACTTTCTCCAAAGAGTGGCTGTGCAATCTGGTGAAAAC
CATCCTCGGCGAAGCTGAAAGCTATGGCAATATAAATATGGGCGGCGGCAGCCGCGTTCAAATAGAGTTTGTCAGCGCCA
ACCCCACCGGGCCTATACATATAGGGCATGGGCGGGGGGCAGTGCTGGGCAGCACCCTTTCAAACGTGCTTAAAGCCGCC
GGTTATTATGTGGAAGAGGAGTTTTATATCAATGATGCCGGCAGCCAGATAGACGCTTTCAAACGCACCCTGTTTGCCCG
CTACCAGCAGGCTCTGGGTAAGGAGGCGGCTGTTCCCCAGGATGGTTATCACGGACAGTACATGGTAGAGCTGGCGGCCG
AAATGGTAGCCAAATACGGGGATAAATACCTGCAAATGCCGCTTGAAATAGCCCAAAATGACCTGGGGGAGATAGGCATG
GCACGTATGCTCTGCCTTATCAGTGATGATTTGAAATCCCTCAAGGTGGATTTTGACGTCTGGTTTTCAGAGAGGTCTTT
ATATAGCGGCGGGCAGTACAAAACCGCCATGGATATACTTTTGGCCAACAACTACATTGCCGAAAGGGACAATGCCACCT
GGTTCAGCTCCACCCTGCTGGGAGACAGCAAGGACAACGTAATAGTCCGCAGTGACGGCACACCCACCTATTTTGCGTCT
GATATCGCTTACCACTACAACAAGTTTATTGAACGCAAATTTGACCGGGTTATAAATATCTGGGGGGCAGACCATCAGGG
GCATGTATCCCGCATGAAAGCCATGCTAAGCGCTCTGGGTATCAATCCCGAACGGCTGACTACCCTGCTTTTCCAGATGA
TTACCCTGAAGCGGGGCGGTGAGCTGGTACGCCTTTCCAAACGCACCGGTGAAATGATAAGCCTGAGTGAGGTTATTGAG
GAAGTGGGGGCAGACGCCTGCCGTTTCTTCTTCCTGTCCCGCTCCACCGAAAGCCAGATGGATTTTGATTTGGAACTGGC
CAAGAAGGAATCGGCCGAAAATCCGGTATATTATGTCCAGTATGCCCATGCCCGTATTTGCAGTATTTTGTCTCTGGCAA
AGGAAAAAGGGCTTTCTTACAGCGGCGGGGATACCGCCCTGCTTGGGGAAGAAGCCGAGCTTGAGCTTATCCGCAAGATG
GCCGAACTGCCTGAGATTGTGGAGACTGTGGCCCGCACCCTTGAACCCCACCACCTGACCTATTACGCCCAGGAACTGGC
CAATGCTTTCCACCAGTTTTACAAAGACTGCCGGGTGATTTCAGATAATACTGAACTAAGCTCAGCCCGCCTGAAACTGG
TAGACGCCAGCCGTATTGTGCTGGCCAGAACCTTGCACCTTATGGGTATGACCTCACCCCAAAGCATGTAA

Upstream 100 bases:

>100_bases
TAAATCATAAAAAACCCCTCCAGACATTATCATCTTCCCATTATGTGATATAATCTATTTTCCAGTTTAAACCGCAATAA
TAAATACTCGGAGTTTAGTC

Downstream 100 bases:

>100_bases
AGAGATACTCCGTTTAAGTTGCAATCAGGGCAGACCATAAATGGTCTGCCCTTTTTAGTGCCTACTTTGCCGAAATAGAT
TAGAGGACCAGACAGGTAAC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MNSILAIKNIIIESLSQALEKARQEGQIPALSVDISIEHPQKTNYGDYATSLPLRLAKATGKRPMELAEILAGYIEPGEG
IAKVSVAPPGFINFTFSKEWLCNLVKTILGEAESYGNINMGGGSRVQIEFVSANPTGPIHIGHGRGAVLGSTLSNVLKAA
GYYVEEEFYINDAGSQIDAFKRTLFARYQQALGKEAAVPQDGYHGQYMVELAAEMVAKYGDKYLQMPLEIAQNDLGEIGM
ARMLCLISDDLKSLKVDFDVWFSERSLYSGGQYKTAMDILLANNYIAERDNATWFSSTLLGDSKDNVIVRSDGTPTYFAS
DIAYHYNKFIERKFDRVINIWGADHQGHVSRMKAMLSALGINPERLTTLLFQMITLKRGGELVRLSKRTGEMISLSEVIE
EVGADACRFFFLSRSTESQMDFDLELAKKESAENPVYYVQYAHARICSILSLAKEKGLSYSGGDTALLGEEAELELIRKM
AELPEIVETVARTLEPHHLTYYAQELANAFHQFYKDCRVISDNTELSSARLKLVDASRIVLARTLHLMGMTSPQSM

Sequences:

>Translated_556_residues
MNSILAIKNIIIESLSQALEKARQEGQIPALSVDISIEHPQKTNYGDYATSLPLRLAKATGKRPMELAEILAGYIEPGEG
IAKVSVAPPGFINFTFSKEWLCNLVKTILGEAESYGNINMGGGSRVQIEFVSANPTGPIHIGHGRGAVLGSTLSNVLKAA
GYYVEEEFYINDAGSQIDAFKRTLFARYQQALGKEAAVPQDGYHGQYMVELAAEMVAKYGDKYLQMPLEIAQNDLGEIGM
ARMLCLISDDLKSLKVDFDVWFSERSLYSGGQYKTAMDILLANNYIAERDNATWFSSTLLGDSKDNVIVRSDGTPTYFAS
DIAYHYNKFIERKFDRVINIWGADHQGHVSRMKAMLSALGINPERLTTLLFQMITLKRGGELVRLSKRTGEMISLSEVIE
EVGADACRFFFLSRSTESQMDFDLELAKKESAENPVYYVQYAHARICSILSLAKEKGLSYSGGDTALLGEEAELELIRKM
AELPEIVETVARTLEPHHLTYYAQELANAFHQFYKDCRVISDNTELSSARLKLVDASRIVLARTLHLMGMTSPQSM
>Mature_556_residues
MNSILAIKNIIIESLSQALEKARQEGQIPALSVDISIEHPQKTNYGDYATSLPLRLAKATGKRPMELAEILAGYIEPGEG
IAKVSVAPPGFINFTFSKEWLCNLVKTILGEAESYGNINMGGGSRVQIEFVSANPTGPIHIGHGRGAVLGSTLSNVLKAA
GYYVEEEFYINDAGSQIDAFKRTLFARYQQALGKEAAVPQDGYHGQYMVELAAEMVAKYGDKYLQMPLEIAQNDLGEIGM
ARMLCLISDDLKSLKVDFDVWFSERSLYSGGQYKTAMDILLANNYIAERDNATWFSSTLLGDSKDNVIVRSDGTPTYFAS
DIAYHYNKFIERKFDRVINIWGADHQGHVSRMKAMLSALGINPERLTTLLFQMITLKRGGELVRLSKRTGEMISLSEVIE
EVGADACRFFFLSRSTESQMDFDLELAKKESAENPVYYVQYAHARICSILSLAKEKGLSYSGGDTALLGEEAELELIRKM
AELPEIVETVARTLEPHHLTYYAQELANAFHQFYKDCRVISDNTELSSARLKLVDASRIVLARTLHLMGMTSPQSM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=601, Percent_Identity=22.2961730449251, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI1788184, Length=599, Percent_Identity=23.2053422370618, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71985061, Length=616, Percent_Identity=23.0519480519481, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71985068, Length=578, Percent_Identity=22.8373702422145, Blast_Score=100, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320548, Length=560, Percent_Identity=24.8214285714286, Blast_Score=126, Evalue=8e-30,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_DEHE1 (Q3Z717)

Other databases:

- EMBL:   CP000027
- RefSeq:   YP_181982.1
- ProteinModelPortal:   Q3Z717
- STRING:   Q3Z717
- GeneID:   3229412
- GenomeReviews:   CP000027_GR
- KEGG:   det:DET1270
- NMPDR:   fig|243164.3.peg.1263
- TIGR:   DET1270
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   DETH243164:DET_1270-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61770; Mature: 61770

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSILAIKNIIIESLSQALEKARQEGQIPALSVDISIEHPQKTNYGDYATSLPLRLAKAT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHCHHHHHHHC
GKRPMELAEILAGYIEPGEGIAKVSVAPPGFINFTFSKEWLCNLVKTILGEAESYGNINM
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHCCHHCCCCEEC
GGGSRVQIEFVSANPTGPIHIGHGRGAVLGSTLSNVLKAAGYYVEEEFYINDAGSQIDAF
CCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHH
KRTLFARYQQALGKEAAVPQDGYHGQYMVELAAEMVAKYGDKYLQMPLEIAQNDLGEIGM
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHCCHHHHHCCHHHHHH
ARMLCLISDDLKSLKVDFDVWFSERSLYSGGQYKTAMDILLANNYIAERDNATWFSSTLL
HHHHHHHHHCHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCEECCCCCCEEHHHHC
GDSKDNVIVRSDGTPTYFASDIAYHYNKFIERKFDRVINIWGADHQGHVSRMKAMLSALG
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHC
INPERLTTLLFQMITLKRGGELVRLSKRTGEMISLSEVIEEVGADACRFFFLSRSTESQM
CCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCCHHHHHHHHCCCCCCCC
DFDLELAKKESAENPVYYVQYAHARICSILSLAKEKGLSYSGGDTALLGEEAELELIRKM
CCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHH
AELPEIVETVARTLEPHHLTYYAQELANAFHQFYKDCRVISDNTELSSARLKLVDASRIV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCEEEEECHHHHH
LARTLHLMGMTSPQSM
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNSILAIKNIIIESLSQALEKARQEGQIPALSVDISIEHPQKTNYGDYATSLPLRLAKAT
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHCHHHHHHHC
GKRPMELAEILAGYIEPGEGIAKVSVAPPGFINFTFSKEWLCNLVKTILGEAESYGNINM
CCCHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHCCHHCCCCEEC
GGGSRVQIEFVSANPTGPIHIGHGRGAVLGSTLSNVLKAAGYYVEEEFYINDAGSQIDAF
CCCCEEEEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHH
KRTLFARYQQALGKEAAVPQDGYHGQYMVELAAEMVAKYGDKYLQMPLEIAQNDLGEIGM
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHCCHHHHHCCHHHHHH
ARMLCLISDDLKSLKVDFDVWFSERSLYSGGQYKTAMDILLANNYIAERDNATWFSSTLL
HHHHHHHHHCHHHEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCEECCCCCCEEHHHHC
GDSKDNVIVRSDGTPTYFASDIAYHYNKFIERKFDRVINIWGADHQGHVSRMKAMLSALG
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHC
INPERLTTLLFQMITLKRGGELVRLSKRTGEMISLSEVIEEVGADACRFFFLSRSTESQM
CCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHCCHHHHHHHHCCCCCCCC
DFDLELAKKESAENPVYYVQYAHARICSILSLAKEKGLSYSGGDTALLGEEAELELIRKM
CCCHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHHH
AELPEIVETVARTLEPHHLTYYAQELANAFHQFYKDCRVISDNTELSSARLKLVDASRIV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCEEEEECHHHHH
LARTLHLMGMTSPQSM
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA