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The map label for this gene is fabI1 [H]

Identifier: 57233945

GI number: 57233945

Start: 1160518

End: 1161357

Strand: Direct

Name: fabI1 [H]

Synonym: DET1272

Alternate gene names: 57233945

Gene position: 1160518-1161357 (Clockwise)

Preceding gene: 57233947

Following gene: 57233944

Centisome position: 78.96

GC content: 50.36

Gene sequence:

>840_bases
ATGACTCAAACGTCTTACGGATTGCTCAAGGGTAAAAAAGGAATTATATTCGGCCCCTTAAACGAGCAAAGTCTGGGCTG
GAAAATAGCCCTGGCCTGCCACCGCGAAGGAGCTGAACTGGCTATTTCCAACGTAGCTACCGCCCTTAAAATGGGAAACA
CCGCCGAACTGGCCCGCATTTGCGGCCAAGCCCCGCTGCTGGTTGCAGATGCCACCAGCGATGATGAGCTGAAAGCCCTG
TTTGCCGGACTAAAAACCAGCCTGGGGGAGATAGATTTTATAGTCCATTCGGTAGGTATGAGCGCCAATATCCGCAAGAA
AATACCGTATGAATCTACCAACTATATTTTTTATAACAAAGGGCTGGAGATTTCGGCCATATCCCTGCACAAAATAATCC
GTTATGCCCTTGAAGCCGGGGTATTAAAAGACAACGGCAGCATAGTGGCACTGTCTTATATAGGGGCACAAAGGGTATTT
TCCCAGTACAACGACATGAACGATGCCAAAGCCCTGCTGGAAGCTATTGCCCGAAATTTCGGTTCCCGCCTGGCAGACCG
GGGAATAAGGGTAAACACCGTTTCCCAGTCACCTACCCGCACCTCCGCCGGTTCGGGAATAAGCAATTTTGATGCCATGT
ACGAATACGCAAATCTGCTTGCCCCCTTGGGCAATGCCAGCGGGGAAGAATGCGCTGATTATGTGGTAACCCTGCTTTCA
GACCTCAGCCGCAAGGTTACCATGCAAAACCTTTATCATGACGGGGGGTTTTCCAGTGTAGGTATTTCCGAAAAACTGCT
TGGCCTGCTGGAACGCAGCCAGCCCGAAGCAGGTGTATAA

Upstream 100 bases:

>100_bases
TATTTGAATACGGCAGGCGGTATGGACTATAATATAACACACTTTTTATGCATTTTTTATTTTTGTGACAAATTTATAAA
ATATTTTGACGGGAGATATT

Downstream 100 bases:

>100_bases
TAGCTTAATCCTTTGAAAGAGAGGGTGTGATGGCCAAAAACTTCAGCCGCCTTATGTTTATATCTGTTTTAGTGTTTCTG
GTCAGTTTCTTTATCCACCT

Product: enoyl-(acyl-carrier-protein) reductase, putative

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase 1 [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTQTSYGLLKGKKGIIFGPLNEQSLGWKIALACHREGAELAISNVATALKMGNTAELARICGQAPLLVADATSDDELKAL
FAGLKTSLGEIDFIVHSVGMSANIRKKIPYESTNYIFYNKGLEISAISLHKIIRYALEAGVLKDNGSIVALSYIGAQRVF
SQYNDMNDAKALLEAIARNFGSRLADRGIRVNTVSQSPTRTSAGSGISNFDAMYEYANLLAPLGNASGEECADYVVTLLS
DLSRKVTMQNLYHDGGFSSVGISEKLLGLLERSQPEAGV

Sequences:

>Translated_279_residues
MTQTSYGLLKGKKGIIFGPLNEQSLGWKIALACHREGAELAISNVATALKMGNTAELARICGQAPLLVADATSDDELKAL
FAGLKTSLGEIDFIVHSVGMSANIRKKIPYESTNYIFYNKGLEISAISLHKIIRYALEAGVLKDNGSIVALSYIGAQRVF
SQYNDMNDAKALLEAIARNFGSRLADRGIRVNTVSQSPTRTSAGSGISNFDAMYEYANLLAPLGNASGEECADYVVTLLS
DLSRKVTMQNLYHDGGFSSVGISEKLLGLLERSQPEAGV
>Mature_278_residues
TQTSYGLLKGKKGIIFGPLNEQSLGWKIALACHREGAELAISNVATALKMGNTAELARICGQAPLLVADATSDDELKALF
AGLKTSLGEIDFIVHSVGMSANIRKKIPYESTNYIFYNKGLEISAISLHKIIRYALEAGVLKDNGSIVALSYIGAQRVFS
QYNDMNDAKALLEAIARNFGSRLADRGIRVNTVSQSPTRTSAGSGISNFDAMYEYANLLAPLGNASGEECADYVVTLLSD
LSRKVTMQNLYHDGGFSSVGISEKLLGLLERSQPEAGV

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=265, Percent_Identity=32.0754716981132, Blast_Score=117, Evalue=7e-28,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 29935; Mature: 29803

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTSYGLLKGKKGIIFGPLNEQSLGWKIALACHREGAELAISNVATALKMGNTAELARI
CCCCCCCHHCCCCCEEECCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
CGQAPLLVADATSDDELKALFAGLKTSLGEIDFIVHSVGMSANIRKKIPYESTNYIFYNK
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEEC
GLEISAISLHKIIRYALEAGVLKDNGSIVALSYIGAQRVFSQYNDMNDAKALLEAIARNF
CCEEEHHHHHHHHHHHHHHCEEECCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GSRLADRGIRVNTVSQSPTRTSAGSGISNFDAMYEYANLLAPLGNASGEECADYVVTLLS
HHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
DLSRKVTMQNLYHDGGFSSVGISEKLLGLLERSQPEAGV
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQTSYGLLKGKKGIIFGPLNEQSLGWKIALACHREGAELAISNVATALKMGNTAELARI
CCCCCCHHCCCCCEEECCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
CGQAPLLVADATSDDELKALFAGLKTSLGEIDFIVHSVGMSANIRKKIPYESTNYIFYNK
HCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCEEEEEC
GLEISAISLHKIIRYALEAGVLKDNGSIVALSYIGAQRVFSQYNDMNDAKALLEAIARNF
CCEEEHHHHHHHHHHHHHHCEEECCCCEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GSRLADRGIRVNTVSQSPTRTSAGSGISNFDAMYEYANLLAPLGNASGEECADYVVTLLS
HHHHHHCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
DLSRKVTMQNLYHDGGFSSVGISEKLLGLLERSQPEAGV
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]