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The map label for this gene is bdhA [H]

Identifier: 57233580

GI number: 57233580

Start: 46311

End: 47453

Strand: Direct

Name: bdhA [H]

Synonym: DET0053

Alternate gene names: 57233580

Gene position: 46311-47453 (Clockwise)

Preceding gene: 57233581

Following gene: 57233579

Centisome position: 3.15

GC content: 52.41

Gene sequence:

>1143_bases
ATGATAACAACATTTGAGCTATCCACCCGCATTATCTTCGGGGTGGGCAGCATAAGCAGCCTTAATCACGAAGCTTCACT
GCTGGGCAGGCACGCTTTGCTGGTCACCGGTAAAAATTCGGTACGCCGTTTAGGCATACTGGAACGGGCCGCATTTTTGC
TGAAAGAGGCCTGTATTCAAACCACCCTGTTTGACAGGGTAGAGCCCAACCCCCGTTCGTCTACGGTAGATGAGGCTATT
GCCTTAGCCAGAGAGAAAGGGATAGACCTGATTATTGCTTTGGGCGGCGGAAGCGCTATGGATGCCGCCAAGGCCATTGC
TTTCGGGCTGGCCTGTGAAGGACCTGTTTGGGATTACATAAAACAGGGAGAGTACCCTGAGGGTGATTTTCTGCCTCTTA
TTATGATACCCACCGTTGCCGCCAGCGGCTCGGAGGCAAACGGGAATGCGGTTATTTCCAACTGGGAAAAGCATGAAAAA
AGGGTTATTTCGGATAGCCGTCTTCAGCCCAAAGTATCTCTGGTAGACCCCCTGCTGACCCTCAGCCTGCCTTCCCGCCA
AACAGCCCAGGGCGGAGTAGATATATTCTGCCATCTGGCAGAACCTTATCTGACCGCCGCAGATGATGCTCCCCTGCGGG
ACGGAATGGCTGAACTGGCCATGCGGCTGGTAACAGAATATTTACCCAAAGCGGTTAAGACCCCGCATGACCTTCAGGCC
CGCACCCAGCTTAGCTGGCTTTCAACTATTGCCTGTTCCCAGTTTATGTCACTGGGCGGCAGAAGCGGCGGCATGACCAT
GCACGGCTTGGAGCATGCCTTAAGCGGTTACTATGACATTGCTCACGCTGACGGTTTGGCTGCCCTTTTGCCGGCTTACA
TGAGAAACCTTTACCCGGTGCGGCGGCACCGTATAGAAATGCTGGGGGAAAAAGTATTCGGGCAGACAGACGGGATAGCA
GCAGTTGAAAACTGGCTCAAAAAAAATAATATGGGTTTCAGCCTGAAAGAGCTGGGGGTTTCCGAAGCTAAAATTGATGA
AATGGCGGCGGCGGCAATCGTGATGTCACCCTGGGTGAAAAACCATCCCGGTCTCCTTGACAAGAGGGTGGCTGCAAGTC
TATACTCTGATGCTTTTAATTAA

Upstream 100 bases:

>100_bases
CTCTTCCTAGATATTATCTGGCGGCTGTCTTGCGGCAGGGATAAAAAACGGGAGGTCAGGGGGCTGTTTTAACAGTGCTG
TTTTCTGTTATTATATTTTT

Downstream 100 bases:

>100_bases
GCGCCTTTTACACAGCTTAAAAATCTGAAAAAATCTCCAAGGTTTTTCCCGCTGAACGTGGGGCCGCCCTTGACAGCGGC
TAAAGCAATGGGATATAATA

Product: alcohol dehydrogenase, iron-containing

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MITTFELSTRIIFGVGSISSLNHEASLLGRHALLVTGKNSVRRLGILERAAFLLKEACIQTTLFDRVEPNPRSSTVDEAI
ALAREKGIDLIIALGGGSAMDAAKAIAFGLACEGPVWDYIKQGEYPEGDFLPLIMIPTVAASGSEANGNAVISNWEKHEK
RVISDSRLQPKVSLVDPLLTLSLPSRQTAQGGVDIFCHLAEPYLTAADDAPLRDGMAELAMRLVTEYLPKAVKTPHDLQA
RTQLSWLSTIACSQFMSLGGRSGGMTMHGLEHALSGYYDIAHADGLAALLPAYMRNLYPVRRHRIEMLGEKVFGQTDGIA
AVENWLKKNNMGFSLKELGVSEAKIDEMAAAAIVMSPWVKNHPGLLDKRVAASLYSDAFN

Sequences:

>Translated_380_residues
MITTFELSTRIIFGVGSISSLNHEASLLGRHALLVTGKNSVRRLGILERAAFLLKEACIQTTLFDRVEPNPRSSTVDEAI
ALAREKGIDLIIALGGGSAMDAAKAIAFGLACEGPVWDYIKQGEYPEGDFLPLIMIPTVAASGSEANGNAVISNWEKHEK
RVISDSRLQPKVSLVDPLLTLSLPSRQTAQGGVDIFCHLAEPYLTAADDAPLRDGMAELAMRLVTEYLPKAVKTPHDLQA
RTQLSWLSTIACSQFMSLGGRSGGMTMHGLEHALSGYYDIAHADGLAALLPAYMRNLYPVRRHRIEMLGEKVFGQTDGIA
AVENWLKKNNMGFSLKELGVSEAKIDEMAAAAIVMSPWVKNHPGLLDKRVAASLYSDAFN
>Mature_380_residues
MITTFELSTRIIFGVGSISSLNHEASLLGRHALLVTGKNSVRRLGILERAAFLLKEACIQTTLFDRVEPNPRSSTVDEAI
ALAREKGIDLIIALGGGSAMDAAKAIAFGLACEGPVWDYIKQGEYPEGDFLPLIMIPTVAASGSEANGNAVISNWEKHEK
RVISDSRLQPKVSLVDPLLTLSLPSRQTAQGGVDIFCHLAEPYLTAADDAPLRDGMAELAMRLVTEYLPKAVKTPHDLQA
RTQLSWLSTIACSQFMSLGGRSGGMTMHGLEHALSGYYDIAHADGLAALLPAYMRNLYPVRRHRIEMLGEKVFGQTDGIA
AVENWLKKNNMGFSLKELGVSEAKIDEMAAAAIVMSPWVKNHPGLLDKRVAASLYSDAFN

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=349, Percent_Identity=29.2263610315186, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789386, Length=348, Percent_Identity=31.0344827586207, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI48994951, Length=365, Percent_Identity=28.4931506849315, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87082107, Length=356, Percent_Identity=30.8988764044944, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1789163, Length=354, Percent_Identity=28.2485875706215, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787493, Length=307, Percent_Identity=28.9902280130293, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17537053, Length=299, Percent_Identity=29.0969899665552, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=366, Percent_Identity=30.327868852459, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24657991, Length=394, Percent_Identity=29.9492385786802, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 41173; Mature: 41173

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00913 ADH_IRON_1 ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTFELSTRIIFGVGSISSLNHEASLLGRHALLVTGKNSVRRLGILERAAFLLKEACIQ
CCEEEEECCEEEEECCCCCCCCHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
TTLFDRVEPNPRSSTVDEAIALAREKGIDLIIALGGGSAMDAAKAIAFGLACEGPVWDYI
HHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHH
KQGEYPEGDFLPLIMIPTVAASGSEANGNAVISNWEKHEKRVISDSRLQPKVSLVDPLLT
HCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHHHH
LSLPSRQTAQGGVDIFCHLAEPYLTAADDAPLRDGMAELAMRLVTEYLPKAVKTPHDLQA
CCCCCCCCCCCCCEEEEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RTQLSWLSTIACSQFMSLGGRSGGMTMHGLEHALSGYYDIAHADGLAALLPAYMRNLYPV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RRHRIEMLGEKVFGQTDGIAAVENWLKKNNMGFSLKELGVSEAKIDEMAAAAIVMSPWVK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCC
NHPGLLDKRVAASLYSDAFN
CCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITTFELSTRIIFGVGSISSLNHEASLLGRHALLVTGKNSVRRLGILERAAFLLKEACIQ
CCEEEEECCEEEEECCCCCCCCHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
TTLFDRVEPNPRSSTVDEAIALAREKGIDLIIALGGGSAMDAAKAIAFGLACEGPVWDYI
HHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHH
KQGEYPEGDFLPLIMIPTVAASGSEANGNAVISNWEKHEKRVISDSRLQPKVSLVDPLLT
HCCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHHHH
LSLPSRQTAQGGVDIFCHLAEPYLTAADDAPLRDGMAELAMRLVTEYLPKAVKTPHDLQA
CCCCCCCCCCCCCEEEEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RTQLSWLSTIACSQFMSLGGRSGGMTMHGLEHALSGYYDIAHADGLAALLPAYMRNLYPV
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RRHRIEMLGEKVFGQTDGIAAVENWLKKNNMGFSLKELGVSEAKIDEMAAAAIVMSPWVK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCC
NHPGLLDKRVAASLYSDAFN
CCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]