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The map label for this gene is pbpG [H]

Identifier: 56965657

GI number: 56965657

Start: 4056485

End: 4058611

Strand: Direct

Name: pbpG [H]

Synonym: ABC3899

Alternate gene names: 56965657

Gene position: 4056485-4058611 (Clockwise)

Preceding gene: 56965651

Following gene: 56965659

Centisome position: 94.25

GC content: 48.38

Gene sequence:

>2127_bases
ATGCAGACAGTTACGCGCAAAAAGCGGAAACGCTTTCGCAAAATCAGGCTTATTTGGCGGCTTTTGTTGCTTTCTCTTAT
CGTCATCGCGTTAGGCATTATTCTATTATTATCTTATACGCGCATGCAAGGCCCCCCACCAATTGACGCCGTGCAAACAA
CACAGTTTTTGGCGGCAGACGGAACGGTTATGGGGAAAGAAGAAGCCGGTCAAAACCGCTTTTCTCTCCCGCTAACAGAA
ATGTCACCTTATTTGTTGCAAGCAACAATCGCGATTGAAGACCGAAAGTTTTACTCCCATTACGGCTTTGACCTTAAACG
AATCGGCGGAGCGCTCCTTGCCAATTTGCAATCTGGCTCAAAAGCACAAGGGGCGAGCACCATTACGCAACAATACGCAC
GTAACCTTTATTTGAGCCACGAAAAAACCTATATGCGGAAATGGAATGAGCTGCTTTACGCACTCCGTTTGGAGATGAAT
TTTTCAAAAGACGAGATTTTAGCTGGTTACTTAAACACCGTCTATTATGGGCATGGCGCCTATGGAGTTGAAGCAGCTGC
ACAGCATTTCTTTGGGAAATCGGCAAAAGACGTGTCATTGGCAGAAGCGGCAATGCTTGCAGGCATTCCGAAAGGACCAA
GCTACTATTCGCCATTGAATGATCTCGAAAAAGCGAAAAGCAGGCAAGAGCTGATTTTGGATAGCATGGTTGGGGAAGGC
ATGATTGAGGAGGCAGAAGCAGACAAAGCAAAAGCGGAAAAACTGGTTTTTGCGGACGAAGCTGATAAAGAGGAAGAAGA
AATCGCGCCTTATTTTCAAGACCATGTTAAAGCGCTGCTACACAATGAAGCGCAAATGGACGAAGCGGCCGTTGACACAG
GTGGACTGATCATTGAGACGACGCTTGATCCCGCCTTGCAGCAACAGGCCGAAGATTTGGTCGAAAAGCATATGCCCGAC
AACGGGCTGCAAGTCGCCCTGATCGCCATGGACCCACGCAATGGGGAAGTAAAGGCGCTTGTCGGCGGCACAGATTACAA
TGAAAGTTCCTATAACCGCGCTACACAGGCCATGCGCAACCCTGGGTCGACCATTAAACCATTTTTGTATTACGCTGCAC
TCGAGAACGGTTTTACGCCCGTATCGACGTTTTTAAGTGAAGCGACATCCTTTTCCTATGATGATGGCCGAGAAGACTAC
GCTCCGAGTAACTACAACGACATTTACGCCAATGATTTTATTACAATGCTTGAAGCCATCGCTTACTCAGACAATATTTA
TGCGATGAAAACGCATTTGTCTATTGGCACAGACGAACTAGTAAATGTCTCTGAAAAACTGGGACTTGGTACATTTGAAA
ACCGCCCTTCCCTTGCTTTAGGGGCACAACCTGTCACCGTCCTCGATATCGCCAATGCTTACGCGGCTTTAGCCGACGGA
GGAAAACAACGGGAACCGGTATTCATACGCCAAGTGCGTGACGGCGAGGGAAACAAAGTCTACGAACAAAAACCGCCTGT
CCGCCAAGTCCTCCGTGAAGATACAGCCTTTGTGCTGACCGATATGTTGCGCGGCGTATTTGAACCGGCGCTAAACAGCT
ACACATCGGTTACCGGTGCAAGCGTAGCCGCACAGCTAACGCACCCGACAGCCGGAAAATCTGGATCAACACCTCGGGAC
AGCTGGATGGTTGGCTATACACCACAGCTTGTTACTGCTGTGTGGGTTGGTTTTGATAAAGACAAAGACATCAATCAATC
GGTTGAAGGGCAAATCTCGAAACGGATTTGGGCGGACTTTATGGAAGCAGCGATGGCCAATGAACTAAAGCTTCCGTTTA
AAGAACCGCCAGGGGTTGAAGCCGTTGACATCGACCCCCACACTGGGTTGTTAACGAGCGACGCCTGTCCTAATGGCCGC
ACGACTTACTTTTTAGCAGGAACTGCTCCTGTAAATACTTGCGCTGAGCCAGAGGCAGCCGAAGACTTACAAGAAGAGCC
AGAAACGAAAGATCCAGGCTTTTTCAAACGTTTTTTTAAATGGTTTAGCATTGAAGACGGTGACCCGAGTGATCCCTCTG
GGCCAACCATTCTTGATGAAGGTGAAGAGAGTCCCGCCACTGAATAA

Upstream 100 bases:

>100_bases
AGCGGATGCGTTACGAATTGCAAAGACAACAAGGTTTAAAAAAACCGCTTTTTTCCCAAACTGTATACTAAACAAGTTGC
CGGGGAAAGGATGAAAAGTC

Downstream 100 bases:

>100_bases
GCGAAAAGGAGCTGCACGTTTGTGCAGCTCTCAGCTTCTATCAGTCTGAGTGAGGTTATCGACAAACGCTCGCAGCTACG
ACCATTTGCGCCAATCTATT

Product: penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGPPPIDAVQTTQFLAADGTVMGKEEAGQNRFSLPLTE
MSPYLLQATIAIEDRKFYSHYGFDLKRIGGALLANLQSGSKAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMN
FSKDEILAGYLNTVYYGHGAYGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDLEKAKSRQELILDSMVGEG
MIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLHNEAQMDEAAVDTGGLIIETTLDPALQQQAEDLVEKHMPD
NGLQVALIAMDPRNGEVKALVGGTDYNESSYNRATQAMRNPGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGREDY
APSNYNDIYANDFITMLEAIAYSDNIYAMKTHLSIGTDELVNVSEKLGLGTFENRPSLALGAQPVTVLDIANAYAALADG
GKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAFVLTDMLRGVFEPALNSYTSVTGASVAAQLTHPTAGKSGSTPRD
SWMVGYTPQLVTAVWVGFDKDKDINQSVEGQISKRIWADFMEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDACPNGR
TTYFLAGTAPVNTCAEPEAAEDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSGPTILDEGEESPATE

Sequences:

>Translated_708_residues
MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGPPPIDAVQTTQFLAADGTVMGKEEAGQNRFSLPLTE
MSPYLLQATIAIEDRKFYSHYGFDLKRIGGALLANLQSGSKAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMN
FSKDEILAGYLNTVYYGHGAYGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDLEKAKSRQELILDSMVGEG
MIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLHNEAQMDEAAVDTGGLIIETTLDPALQQQAEDLVEKHMPD
NGLQVALIAMDPRNGEVKALVGGTDYNESSYNRATQAMRNPGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGREDY
APSNYNDIYANDFITMLEAIAYSDNIYAMKTHLSIGTDELVNVSEKLGLGTFENRPSLALGAQPVTVLDIANAYAALADG
GKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAFVLTDMLRGVFEPALNSYTSVTGASVAAQLTHPTAGKSGSTPRD
SWMVGYTPQLVTAVWVGFDKDKDINQSVEGQISKRIWADFMEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDACPNGR
TTYFLAGTAPVNTCAEPEAAEDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSGPTILDEGEESPATE
>Mature_708_residues
MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGPPPIDAVQTTQFLAADGTVMGKEEAGQNRFSLPLTE
MSPYLLQATIAIEDRKFYSHYGFDLKRIGGALLANLQSGSKAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMN
FSKDEILAGYLNTVYYGHGAYGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDLEKAKSRQELILDSMVGEG
MIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLHNEAQMDEAAVDTGGLIIETTLDPALQQQAEDLVEKHMPD
NGLQVALIAMDPRNGEVKALVGGTDYNESSYNRATQAMRNPGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGREDY
APSNYNDIYANDFITMLEAIAYSDNIYAMKTHLSIGTDELVNVSEKLGLGTFENRPSLALGAQPVTVLDIANAYAALADG
GKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAFVLTDMLRGVFEPALNSYTSVTGASVAAQLTHPTAGKSGSTPRD
SWMVGYTPQLVTAVWVGFDKDKDINQSVEGQISKRIWADFMEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDACPNGR
TTYFLAGTAPVNTCAEPEAAEDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSGPTILDEGEESPATE

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=531, Percent_Identity=30.1318267419962, Blast_Score=210, Evalue=3e-55,
Organism=Escherichia coli, GI1788867, Length=550, Percent_Identity=28.1818181818182, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI87082258, Length=317, Percent_Identity=35.6466876971609, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1789601, Length=235, Percent_Identity=34.8936170212766, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 78076; Mature: 78076

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGPPPIDAVQTTQFLAAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
GTVMGKEEAGQNRFSLPLTEMSPYLLQATIAIEDRKFYSHYGFDLKRIGGALLANLQSGS
CCEECHHHCCCCCCCCCHHHCCCCCEEEEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCC
KAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMNFSKDEILAGYLNTVYYGHGA
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCC
YGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDLEKAKSRQELILDSMVGEG
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
MIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLHNEAQMDEAAVDTGGLIIET
HHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
TLDPALQQQAEDLVEKHMPDNGLQVALIAMDPRNGEVKALVGGTDYNESSYNRATQAMRN
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHC
PGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGREDYAPSNYNDIYANDFITMLEAI
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AYSDNIYAMKTHLSIGTDELVNVSEKLGLGTFENRPSLALGAQPVTVLDIANAYAALADG
HHCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHCC
GKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAFVLTDMLRGVFEPALNSYTSVTGA
CCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SVAAQLTHPTAGKSGSTPRDSWMVGYTPQLVTAVWVGFDKDKDINQSVEGQISKRIWADF
HHHHEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
MEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDACPNGRTTYFLAGTAPVNTCAEPEAA
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCHHH
EDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSGPTILDEGEESPATE
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCC
>Mature Secondary Structure
MQTVTRKKRKRFRKIRLIWRLLLLSLIVIALGIILLLSYTRMQGPPPIDAVQTTQFLAAD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCC
GTVMGKEEAGQNRFSLPLTEMSPYLLQATIAIEDRKFYSHYGFDLKRIGGALLANLQSGS
CCEECHHHCCCCCCCCCHHHCCCCCEEEEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCC
KAQGASTITQQYARNLYLSHEKTYMRKWNELLYALRLEMNFSKDEILAGYLNTVYYGHGA
CCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEECCCC
YGVEAAAQHFFGKSAKDVSLAEAAMLAGIPKGPSYYSPLNDLEKAKSRQELILDSMVGEG
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
MIEEAEADKAKAEKLVFADEADKEEEEIAPYFQDHVKALLHNEAQMDEAAVDTGGLIIET
HHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
TLDPALQQQAEDLVEKHMPDNGLQVALIAMDPRNGEVKALVGGTDYNESSYNRATQAMRN
CCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHC
PGSTIKPFLYYAALENGFTPVSTFLSEATSFSYDDGREDYAPSNYNDIYANDFITMLEAI
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
AYSDNIYAMKTHLSIGTDELVNVSEKLGLGTFENRPSLALGAQPVTVLDIANAYAALADG
HHCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHCC
GKQREPVFIRQVRDGEGNKVYEQKPPVRQVLREDTAFVLTDMLRGVFEPALNSYTSVTGA
CCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SVAAQLTHPTAGKSGSTPRDSWMVGYTPQLVTAVWVGFDKDKDINQSVEGQISKRIWADF
HHHHEECCCCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
MEAAMANELKLPFKEPPGVEAVDIDPHTGLLTSDACPNGRTTYFLAGTAPVNTCAEPEAA
HHHHHHHCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCCHHH
EDLQEEPETKDPGFFKRFFKWFSIEDGDPSDPSGPTILDEGEESPATE
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]