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The map label for this gene is glvA [H]

Identifier: 56965343

GI number: 56965343

Start: 3727318

End: 3728643

Strand: Direct

Name: glvA [H]

Synonym: ABC3581

Alternate gene names: 56965343

Gene position: 3727318-3728643 (Clockwise)

Preceding gene: 56965342

Following gene: 56965363

Centisome position: 86.6

GC content: 42.91

Gene sequence:

>1326_bases
ATGAAAACATTTAACATTACCATCGCTGGAGGCGGAAGCACATTTACACCAGGGATTATTTTGATGCTGCTCGACTATTT
AGATGAGTTCCCCATCGATACGATTAAACTTTACGACAATGATGGCGATAGGCAAAAAACGATTGCCGATGCGTGCGCGA
TTTTATTAAAAGAACGTGCCCCAGAAGTACGTCTACTAGCAAGCACAAATCCAGAAGAAGCATTTACAAATATCGATTTT
GTCATGGCCCATATCCGTGTTGGCAAATACGCCATGCGTGAGCTAGATGAGAAAATTCCATTGAAACATGGTGTTGTCGG
ACAAGAAACTTGCGGGCCTGGCGGAATCGCTTATGGGATGCGTTCGATTCCAGGCGTATTGGAACTAATCGATTATATGG
AAAAATATTCACCCGAAGCCTGGATGCTAAACTACTCAAACCCAGCAGCAATTGTCGCAGAAGCAACACGCAAACTAAGA
CCCCATTCTAAAGTGTTAAACATTTGTGATATGCCGATTGGCATTGAAGAACTAATCGCCAAAAACTTAGGATTCGCCTC
ACGCAAAGAAATGGAAGTCGACTATTATGGCTTGAATCACTTTGGCTGGTGGACAGATATTCGAGATAAAAACGGACTCA
GCTTAATGCCTGACGTGATTAAGCATGTGAGCCAACATGGTTATGCGACAGACGGAACATCCGAACTCGAACAGCAAGAA
AGCTGGAATAGCACACTAAAAAAAGCAAGAGATGTACAAGCACTCGATCCAGAAACGGTGCCAAACACATATCTAAAATA
TTACTTATACCCAGACTACGAAGTGGCGCATTCAAATAAAGAATACACACGGGCCAACGAAGTCATGGAAGGTCGCGAAA
AATTTGTTTTCGGTGAATGTCAAGCTATTATTGACAAAGGCACGGCAAAAGAAACAAAGCTAGTCATTGACGAGCACGCT
TCCTACATCGTTGATTTAGCAAAAGCCATCGCCTTTAACACAAAAGAACGGATGTTAATGATTGTCGAAAACAATGGCGC
CATTCCGAACTTCGACCCAACAGCAATGGTAGAAATCCCGTGCCTCGTCGGCAGCAATGGCCCAGAAAAACTAGTTGTCG
GAGAAATCCCTAGATTCCAAAAGAGCCTCATGGAGCAACAAGTTGGCGTCGAAAAATTAGTAGTAGAAGCGTTTGAAGAA
GGTTCCTACCAAAAACTATGGCAAGCCATCACATTATCGAAAACCGTGCCAAGTGCAAAAGTAGCAAAAGATATACTAGA
CGACTTAATCGAAGCGAATAAAGCATTTTGGCCAGCGTTGAAATAG

Upstream 100 bases:

>100_bases
GCGGCCAAAGCATACAAATTATTGTTGGTTTGAGTGTACCGCAAGTGAGAGATTCCTTTGAAGCAAAATTATAAATATAT
AGGAGAGGGAGAGATTTACT

Downstream 100 bases:

>100_bases
ACAATAAAAACGAAAAGCAATATGGGCGTCGGTGCGCCTATATTGCTTATTTGGTTTTTCGAACTTGCTTTTTGCATGAC
TAGTCGTTATCGCAAGCGAA

Product: maltose-6'-phosphate glucosidase

Products: NA

Alternate protein names: 6-phospho-alpha-D-glucosidase [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKTFNITIAGGGSTFTPGIILMLLDYLDEFPIDTIKLYDNDGDRQKTIADACAILLKERAPEVRLLASTNPEEAFTNIDF
VMAHIRVGKYAMRELDEKIPLKHGVVGQETCGPGGIAYGMRSIPGVLELIDYMEKYSPEAWMLNYSNPAAIVAEATRKLR
PHSKVLNICDMPIGIEELIAKNLGFASRKEMEVDYYGLNHFGWWTDIRDKNGLSLMPDVIKHVSQHGYATDGTSELEQQE
SWNSTLKKARDVQALDPETVPNTYLKYYLYPDYEVAHSNKEYTRANEVMEGREKFVFGECQAIIDKGTAKETKLVIDEHA
SYIVDLAKAIAFNTKERMLMIVENNGAIPNFDPTAMVEIPCLVGSNGPEKLVVGEIPRFQKSLMEQQVGVEKLVVEAFEE
GSYQKLWQAITLSKTVPSAKVAKDILDDLIEANKAFWPALK

Sequences:

>Translated_441_residues
MKTFNITIAGGGSTFTPGIILMLLDYLDEFPIDTIKLYDNDGDRQKTIADACAILLKERAPEVRLLASTNPEEAFTNIDF
VMAHIRVGKYAMRELDEKIPLKHGVVGQETCGPGGIAYGMRSIPGVLELIDYMEKYSPEAWMLNYSNPAAIVAEATRKLR
PHSKVLNICDMPIGIEELIAKNLGFASRKEMEVDYYGLNHFGWWTDIRDKNGLSLMPDVIKHVSQHGYATDGTSELEQQE
SWNSTLKKARDVQALDPETVPNTYLKYYLYPDYEVAHSNKEYTRANEVMEGREKFVFGECQAIIDKGTAKETKLVIDEHA
SYIVDLAKAIAFNTKERMLMIVENNGAIPNFDPTAMVEIPCLVGSNGPEKLVVGEIPRFQKSLMEQQVGVEKLVVEAFEE
GSYQKLWQAITLSKTVPSAKVAKDILDDLIEANKAFWPALK
>Mature_441_residues
MKTFNITIAGGGSTFTPGIILMLLDYLDEFPIDTIKLYDNDGDRQKTIADACAILLKERAPEVRLLASTNPEEAFTNIDF
VMAHIRVGKYAMRELDEKIPLKHGVVGQETCGPGGIAYGMRSIPGVLELIDYMEKYSPEAWMLNYSNPAAIVAEATRKLR
PHSKVLNICDMPIGIEELIAKNLGFASRKEMEVDYYGLNHFGWWTDIRDKNGLSLMPDVIKHVSQHGYATDGTSELEQQE
SWNSTLKKARDVQALDPETVPNTYLKYYLYPDYEVAHSNKEYTRANEVMEGREKFVFGECQAIIDKGTAKETKLVIDEHA
SYIVDLAKAIAFNTKERMLMIVENNGAIPNFDPTAMVEIPCLVGSNGPEKLVVGEIPRFQKSLMEQQVGVEKLVVEAFEE
GSYQKLWQAITLSKTVPSAKVAKDILDDLIEANKAFWPALK

Specific function: Hydrolyzes a wide variety of 6-phospho-alpha-D- glucosides including maltose-6'P, trehalose-6P and the 6'- phosphorylated derivatives of the five linkage-isomeric alpha-D- glucosyl-D-fructoses:trehalulose-6'P, turanose-6'P, maltulose- 6'P, leucrose-6'P, a

COG id: COG1486

COG function: function code G; Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1788029, Length=458, Percent_Identity=26.4192139737991, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1790560, Length=227, Percent_Identity=26.431718061674, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019802
- InterPro:   IPR001088
- InterPro:   IPR022616
- InterPro:   IPR015955
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02056 Glyco_hydro_4; PF11975 Glyco_hydro_4C [H]

EC number: =3.2.1.122 [H]

Molecular weight: Translated: 49444; Mature: 49444

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01324 GLYCOSYL_HYDROL_F4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFNITIAGGGSTFTPGIILMLLDYLDEFPIDTIKLYDNDGDRQKTIADACAILLKERA
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
PEVRLLASTNPEEAFTNIDFVMAHIRVGKYAMRELDEKIPLKHGVVGQETCGPGGIAYGM
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHH
RSIPGVLELIDYMEKYSPEAWMLNYSNPAAIVAEATRKLRPHSKVLNICDMPIGIEELIA
HHCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHH
KNLGFASRKEMEVDYYGLNHFGWWTDIRDKNGLSLMPDVIKHVSQHGYATDGTSELEQQE
HHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
SWNSTLKKARDVQALDPETVPNTYLKYYLYPDYEVAHSNKEYTRANEVMEGREKFVFGEC
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
QAIIDKGTAKETKLVIDEHASYIVDLAKAIAFNTKERMLMIVENNGAIPNFDPTAMVEIP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEE
CLVGSNGPEKLVVGEIPRFQKSLMEQQVGVEKLVVEAFEEGSYQKLWQAITLSKTVPSAK
EEECCCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
VAKDILDDLIEANKAFWPALK
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKTFNITIAGGGSTFTPGIILMLLDYLDEFPIDTIKLYDNDGDRQKTIADACAILLKERA
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCC
PEVRLLASTNPEEAFTNIDFVMAHIRVGKYAMRELDEKIPLKHGVVGQETCGPGGIAYGM
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHH
RSIPGVLELIDYMEKYSPEAWMLNYSNPAAIVAEATRKLRPHSKVLNICDMPIGIEELIA
HHCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHH
KNLGFASRKEMEVDYYGLNHFGWWTDIRDKNGLSLMPDVIKHVSQHGYATDGTSELEQQE
HHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHH
SWNSTLKKARDVQALDPETVPNTYLKYYLYPDYEVAHSNKEYTRANEVMEGREKFVFGEC
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
QAIIDKGTAKETKLVIDEHASYIVDLAKAIAFNTKERMLMIVENNGAIPNFDPTAMVEIP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEE
CLVGSNGPEKLVVGEIPRFQKSLMEQQVGVEKLVVEAFEEGSYQKLWQAITLSKTVPSAK
EEECCCCCCEEEECCCCHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHH
VAKDILDDLIEANKAFWPALK
HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9209025; 7730284; 11882720 [H]