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The map label for this gene is ccpA [H]

Identifier: 56965240

GI number: 56965240

Start: 3610482

End: 3611510

Strand: Direct

Name: ccpA [H]

Synonym: ABC3478

Alternate gene names: 56965240

Gene position: 3610482-3611510 (Clockwise)

Preceding gene: 56965239

Following gene: 56965242

Centisome position: 83.89

GC content: 45.68

Gene sequence:

>1029_bases
TTGAACAAACCAACCATTAAAGATGTAGCCAAAGAAGCAGGCGTTTCGATTGCCACTGTTTCCCGCGTATTAAACAACGG
AATTGGCTATTCTATAAAAACAAAACAACATGTGCTAAAAACAATCGAAGAAATGGGTTATTCCCCAAATGCGATTGCCC
GCGGCCTCATTAATAAGCAAAGCAATACGATTGGCGTTTTGTTTCCAGAAATATCAGGACTTGTCAGCGCTGAAATTCTT
CAAGGAATAGAGGAAGCTGCACATGCGAGAGGGAAAAGCATTGTCATTTGCAATACAGCCTCTAGCGGCCATAAAACAAA
AGAATACTTAAAGTTGTTGCAAGAAAAACAAGTAGACGGCATTTTATTTGCAAGCCAACTGCTAACATTGGAATATGTGG
CAATCGTCCGCAAAATGGGCGTGCCTGTTGTCACCGTATCTGCTTATTCGGAAGACCCAACGATACCAGCTGTCCAAGTC
GACAATGAAACGGCAGCTTATGATGCGGTCTGTTATTTCATTCAGCAAGGCCATACAGAGATCGGTATGATTAGCGGAAA
CCCGTCTGATTTGTTGGCTGGAGCGCCACGAATGGCCGGTTACAAACGGGCGCTCAAGGAAGCGGGAATTGCTTATGTGC
CTACGAAAGTTGCCTGGGACAAAGGGTTCTATTTTGAAGATGGGCAGAAAGCCTTTCAACGGCTTTACACCGATCATCCG
AATTTGACAGCTATCTTTTCGGCAAGCGATGAACTCGCGATCGGTGCCATGTCCGCCGCTACTGCAAAAGGGCTTCGCAT
TCCGGAAGATCTTTCTGTTATCGGCTTTGATGGCACCAAGCTCGCAAAAATGGCCGTTCCTCCTTTAACAACCGTTTCGC
AACATTTTTTTAGCATGGGCAAAACGGCTGCTAACTTGCTGTTTGATTCAATCGCAACCGGGCAAGCAAGTTCAGGACGC
ATCATCCGACATGAACTCATCAAAAGGCACTCCGTCCAGATGCCCTCATCCACTAAAACGATGGATTAA

Upstream 100 bases:

>100_bases
CAGTAAATGTACTCGTGTTGCTTCATGAAAGCGCTTGACTATTTATTATAACGCTCCCATACTAAACTTAGGAAAGTGTG
TTTTAGGGGGAATGACGCGA

Downstream 100 bases:

>100_bases
ACACGCTCTTTAAAGGGTTTTTAAGACTATTCAGGAATGCCCTGATAAAGTCGTGATCTCGTCTTCTGTCTTTTTCTCGA
TCGATTGCTCATAATTTGCA

Product: catabolite control protein A, glucose-resistance amylase regulator

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNKPTIKDVAKEAGVSIATVSRVLNNGIGYSIKTKQHVLKTIEEMGYSPNAIARGLINKQSNTIGVLFPEISGLVSAEIL
QGIEEAAHARGKSIVICNTASSGHKTKEYLKLLQEKQVDGILFASQLLTLEYVAIVRKMGVPVVTVSAYSEDPTIPAVQV
DNETAAYDAVCYFIQQGHTEIGMISGNPSDLLAGAPRMAGYKRALKEAGIAYVPTKVAWDKGFYFEDGQKAFQRLYTDHP
NLTAIFSASDELAIGAMSAATAKGLRIPEDLSVIGFDGTKLAKMAVPPLTTVSQHFFSMGKTAANLLFDSIATGQASSGR
IIRHELIKRHSVQMPSSTKTMD

Sequences:

>Translated_342_residues
MNKPTIKDVAKEAGVSIATVSRVLNNGIGYSIKTKQHVLKTIEEMGYSPNAIARGLINKQSNTIGVLFPEISGLVSAEIL
QGIEEAAHARGKSIVICNTASSGHKTKEYLKLLQEKQVDGILFASQLLTLEYVAIVRKMGVPVVTVSAYSEDPTIPAVQV
DNETAAYDAVCYFIQQGHTEIGMISGNPSDLLAGAPRMAGYKRALKEAGIAYVPTKVAWDKGFYFEDGQKAFQRLYTDHP
NLTAIFSASDELAIGAMSAATAKGLRIPEDLSVIGFDGTKLAKMAVPPLTTVSQHFFSMGKTAANLLFDSIATGQASSGR
IIRHELIKRHSVQMPSSTKTMD
>Mature_342_residues
MNKPTIKDVAKEAGVSIATVSRVLNNGIGYSIKTKQHVLKTIEEMGYSPNAIARGLINKQSNTIGVLFPEISGLVSAEIL
QGIEEAAHARGKSIVICNTASSGHKTKEYLKLLQEKQVDGILFASQLLTLEYVAIVRKMGVPVVTVSAYSEDPTIPAVQV
DNETAAYDAVCYFIQQGHTEIGMISGNPSDLLAGAPRMAGYKRALKEAGIAYVPTKVAWDKGFYFEDGQKAFQRLYTDHP
NLTAIFSASDELAIGAMSAATAKGLRIPEDLSVIGFDGTKLAKMAVPPLTTVSQHFFSMGKTAANLLFDSIATGQASSGR
IIRHELIKRHSVQMPSSTKTMD

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=330, Percent_Identity=38.1818181818182, Blast_Score=214, Evalue=7e-57,
Organism=Escherichia coli, GI1787948, Length=331, Percent_Identity=34.7432024169184, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1790194, Length=323, Percent_Identity=33.4365325077399, Blast_Score=160, Evalue=8e-41,
Organism=Escherichia coli, GI1789068, Length=336, Percent_Identity=30.6547619047619, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=31.9277108433735, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI48994940, Length=311, Percent_Identity=28.2958199356913, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789202, Length=340, Percent_Identity=29.4117647058824, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1786540, Length=341, Percent_Identity=30.2052785923754, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790715, Length=310, Percent_Identity=26.4516129032258, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=27.6729559748428, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789456, Length=324, Percent_Identity=29.0123456790123, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787906, Length=257, Percent_Identity=29.5719844357977, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790689, Length=322, Percent_Identity=27.0186335403727, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1786268, Length=314, Percent_Identity=22.9299363057325, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36780; Mature: 36780

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2 ; PS00923 ASP_GLU_RACEMASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPTIKDVAKEAGVSIATVSRVLNNGIGYSIKTKQHVLKTIEEMGYSPNAIARGLINKQ
CCCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHCCC
SNTIGVLFPEISGLVSAEILQGIEEAAHARGKSIVICNTASSGHKTKEYLKLLQEKQVDG
CCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCH
ILFASQLLTLEYVAIVRKMGVPVVTVSAYSEDPTIPAVQVDNETAAYDAVCYFIQQGHTE
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHCCCCE
IGMISGNPSDLLAGAPRMAGYKRALKEAGIAYVPTKVAWDKGFYFEDGQKAFQRLYTDHP
EEEECCCHHHHHCCCCHHHHHHHHHHHCCCEEECCEEEECCCCEECCHHHHHHHHHCCCC
NLTAIFSASDELAIGAMSAATAKGLRIPEDLSVIGFDGTKLAKMAVPPLTTVSQHFFSMG
CEEEEEECCCCCEEEHHHHHHHCCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHH
KTAANLLFDSIATGQASSGRIIRHELIKRHSVQMPSSTKTMD
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNKPTIKDVAKEAGVSIATVSRVLNNGIGYSIKTKQHVLKTIEEMGYSPNAIARGLINKQ
CCCCCHHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHCCC
SNTIGVLFPEISGLVSAEILQGIEEAAHARGKSIVICNTASSGHKTKEYLKLLQEKQVDG
CCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCH
ILFASQLLTLEYVAIVRKMGVPVVTVSAYSEDPTIPAVQVDNETAAYDAVCYFIQQGHTE
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHCCCCE
IGMISGNPSDLLAGAPRMAGYKRALKEAGIAYVPTKVAWDKGFYFEDGQKAFQRLYTDHP
EEEECCCHHHHHCCCCHHHHHHHHHHHCCCEEECCEEEECCCCEECCHHHHHHHHHCCCC
NLTAIFSASDELAIGAMSAATAKGLRIPEDLSVIGFDGTKLAKMAVPPLTTVSQHFFSMG
CEEEEEECCCCCEEEHHHHHHHCCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHH
KTAANLLFDSIATGQASSGRIIRHELIKRHSVQMPSSTKTMD
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]