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The map label for this gene is uppP

Identifier: 56965015

GI number: 56965015

Start: 3375030

End: 3375857

Strand: Direct

Name: uppP

Synonym: ABC3251

Alternate gene names: 56965015

Gene position: 3375030-3375857 (Clockwise)

Preceding gene: 56965014

Following gene: 56965020

Centisome position: 78.42

GC content: 46.62

Gene sequence:

>828_bases
ATGGATGTTTGGGAATGGGTTGTTGCCGCTATCCTTGGCCTAGTCGAAGGATTGACGGAATATGCGCCAGTGTCATCAAC
AGGGCATATGATCATAGTGGATGATTTATGGCTCAAATCAAGCGAGTTGGTCGGGTCACAAAATGCCTACGTGTTTAAAA
TTGTGATCCAGCTAGGATCGATCTTAGCAGTGGCGCTTTTGTTCAAGGACCGCCTCTTGCAATTAGCAGGCTTTAAAAAA
CAAGCAGCAACACAGAGCGAAGGACGGGGTTTGACGTTAGGAAAAGTTGCCGTCGGCTTGTTGCCAGCTGCAGTGCTCGG
TTTATTATTTGAGGATAAAATGGAGTCGATTTTCCATGTTCGCACGGTCGCATTTGCTTTAATTGCTGGTGCTTTTCTCA
TGATTGCCGCCGATTTTATAAACAAACGGAACAATAAGAAGAAACAGCAAGTAGACGACATTTCTTACAAACAAGCACTG
GCAATTGGGCTATTCCAATGCCTTGCCCTTTGGCCAGGCTTTTCCCGTTCTGGCTCAACGATATCAGGCGGTGTCATGCT
TGGCTTAACGCACCGAGCAGCAGCAAACTTCACCTTTATTATGGCGATCCCAATTATGGTTGGCGCTAGTGCGCTGTCAC
TGATCAAGAATTGGGACGCCCTTGACATAAGCTTGCTGCCCTTTTACGCCACCGGCTTTATTAGTGCCTTTCTCGTTTCC
CTTGTGGTAGTGCGGTTCTTTTTAAAGCTGATTAACAAAATCAAGCTTGTCCCGTTCGCGCTGTACCGGATTGCTCTGGG
ATTGCTGCTGTTGTTTTTGTTTTCGTAG

Upstream 100 bases:

>100_bases
TGACAATCTCCCATCAGAAATCGACAAGAATAAACACGCCTTATTCTTATAAAACGTGTATGATTTAGCTTGAACAGAAT
CGATAGAATGGAGACTTGCG

Downstream 100 bases:

>100_bases
AAGTCATAAGCAAGCGAATGCGTTTAGGCATTCGCTTGCTTTGTTTTGCCGAAAATCGATTCACTAGGGAACAGAGCACG
CCTACTGGCTTTAACGTTGT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 2; Undecaprenyl pyrophosphate phosphatase 2

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MDVWEWVVAAILGLVEGLTEYAPVSSTGHMIIVDDLWLKSSELVGSQNAYVFKIVIQLGSILAVALLFKDRLLQLAGFKK
QAATQSEGRGLTLGKVAVGLLPAAVLGLLFEDKMESIFHVRTVAFALIAGAFLMIAADFINKRNNKKKQQVDDISYKQAL
AIGLFQCLALWPGFSRSGSTISGGVMLGLTHRAAANFTFIMAIPIMVGASALSLIKNWDALDISLLPFYATGFISAFLVS
LVVVRFFLKLINKIKLVPFALYRIALGLLLLFLFS

Sequences:

>Translated_275_residues
MDVWEWVVAAILGLVEGLTEYAPVSSTGHMIIVDDLWLKSSELVGSQNAYVFKIVIQLGSILAVALLFKDRLLQLAGFKK
QAATQSEGRGLTLGKVAVGLLPAAVLGLLFEDKMESIFHVRTVAFALIAGAFLMIAADFINKRNNKKKQQVDDISYKQAL
AIGLFQCLALWPGFSRSGSTISGGVMLGLTHRAAANFTFIMAIPIMVGASALSLIKNWDALDISLLPFYATGFISAFLVS
LVVVRFFLKLINKIKLVPFALYRIALGLLLLFLFS
>Mature_275_residues
MDVWEWVVAAILGLVEGLTEYAPVSSTGHMIIVDDLWLKSSELVGSQNAYVFKIVIQLGSILAVALLFKDRLLQLAGFKK
QAATQSEGRGLTLGKVAVGLLPAAVLGLLFEDKMESIFHVRTVAFALIAGAFLMIAADFINKRNNKKKQQVDDISYKQAL
AIGLFQCLALWPGFSRSGSTISGGVMLGLTHRAAANFTFIMAIPIMVGASALSLIKNWDALDISLLPFYATGFISAFLVS
LVVVRFFLKLINKIKLVPFALYRIALGLLLLFLFS

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=265, Percent_Identity=48.6792452830189, Blast_Score=249, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP2_BACSK (Q5WCX5)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_176746.1
- STRING:   Q5WCX5
- EnsemblBacteria:   EBBACT00000049500
- GeneID:   3200742
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC3251
- NMPDR:   fig|66692.3.peg.3232
- eggNOG:   COG1968
- GeneTree:   EBGT00050000002490
- HOGENOM:   HBG391969
- OMA:   IGHFIGF
- ProtClustDB:   PRK00281
- BioCyc:   BCLA66692:ABC3251-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29930; Mature: 29930

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1f909cb0)-; HASH(0x1f5c1df4)-; HASH(0x1fd5bc30)-; HASH(0x1fd5a118)-; HASH(0x1fd59ea8)-; HASH(0x1f8a3470)-; HASH(0x1fd5a0a0)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVWEWVVAAILGLVEGLTEYAPVSSTGHMIIVDDLWLKSSELVGSQNAYVFKIVIQLGS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHCHHHHCCCCCHHHHHHHHHHHH
ILAVALLFKDRLLQLAGFKKQAATQSEGRGLTLGKVAVGLLPAAVLGLLFEDKMESIFHV
HHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTVAFALIAGAFLMIAADFINKRNNKKKQQVDDISYKQALAIGLFQCLALWPGFSRSGST
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
ISGGVMLGLTHRAAANFTFIMAIPIMVGASALSLIKNWDALDISLLPFYATGFISAFLVS
EECCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
LVVVRFFLKLINKIKLVPFALYRIALGLLLLFLFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MDVWEWVVAAILGLVEGLTEYAPVSSTGHMIIVDDLWLKSSELVGSQNAYVFKIVIQLGS
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHCHHHHCCCCCHHHHHHHHHHHH
ILAVALLFKDRLLQLAGFKKQAATQSEGRGLTLGKVAVGLLPAAVLGLLFEDKMESIFHV
HHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTVAFALIAGAFLMIAADFINKRNNKKKQQVDDISYKQALAIGLFQCLALWPGFSRSGST
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
ISGGVMLGLTHRAAANFTFIMAIPIMVGASALSLIKNWDALDISLLPFYATGFISAFLVS
EECCEEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
LVVVRFFLKLINKIKLVPFALYRIALGLLLLFLFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA