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The map label for this gene is thrC [H]

Identifier: 56964947

GI number: 56964947

Start: 3306144

End: 3307274

Strand: Direct

Name: thrC [H]

Synonym: ABC3183

Alternate gene names: 56964947

Gene position: 3306144-3307274 (Clockwise)

Preceding gene: 56964945

Following gene: 56964948

Centisome position: 76.82

GC content: 49.6

Gene sequence:

>1131_bases
TTGATGAAGCAATCGTACGTTTGCCGCAGTTGCCATACCACTTACCCTGTTTCGCGTGATCTTTGGAAGTGCCTTTGTGG
CGGTCTGCTCGACCTTGACAAACAAATGCCATTGCTCGAACCTACGGCTTGGGAATCTGGTCCTCCTACACTATGGCGCT
TTTTGGACGCATTGCCGTTTGAAAAAGACGCGAAAAGTTGGCAAAACGTGACTTTAGGCGAAGGCAATACGCCGCTTCTA
CCTGTTTCTGCTGATAAGCCGAATGTCTATGTAAAAGTCGACTATTTAATGCCGACGCTCTCTTTTAAAGACCGTGGCGC
TGCTGTCCTAATCGCAAAAGCGCTAGAACTTGGTGCCACATCTGTCATTGCCGATAGCAGCGGCAATGCAGGGACTGCCG
TTTCGGCCTATGCAGCAAGAGCTGGCATTGCTTGCGAAGTGTTTTGCAGCAATACGGTTTCCCCGAAAAAACAAGCACAA
ATGGCAGCATACAATGCCAAGGTCCACACCATTGCCGGTACACGTGAAGATGTCGCACGTGCCGCACAGCAAAAAGCCGC
CAACTTAGAAGAAGGCGGTTTTTATGCAAGCCATGTGTATAATCCCTACTTTTATGAAGGCACGAAAACGTATGCGTACG
AAATTTATGAACAGCTTGGCGACGCACCAGACACAGTGATTATCCCTGTTGGCAATGGCACCCTTTTACTCGGTGCTTAT
TACGGCTTTTCTGAGCTTTTAGCGAACCGTCTCATTGGCAAATGCCCGAAAATCGTGGCCGTGCAAGCTCAACAATGCGC
CCCTCTTGCTCATGCGTTTGCCACAGGAGAACCATCTATTACGCCTATAGTAGGCCAAACGACGATTGCTGAAGGGATTG
CGATCGCTGCACCACCTCGTGCAACGCAAATATTAGAGGCAGTCCGCAATACGGGCGGCACCTTCATAACTGTTAGCGAA
GCACAAATAGCGAAAGCACGCTCGGCACTTGCCAAGCAAGGTTTTGATGTGGAACCTACTAGCGCCGCTACCTACGCCGC
CCTTCACGTTTACCGACACTGTGAAACAGAAACGATCGTCATCCCTTTATGTGGTTCTGGGACAAAGGCAAGTGACCACA
TAGCAAAATAA

Upstream 100 bases:

>100_bases
ATTGTTTATAAAACTAGTAGTTTTTTGATTTTCCCAATAAAAAAGTTAACATTTCTCTCAAACTGGCATTTTCTATGAAT
GTTACAAAAGGAGCGATCTA

Downstream 100 bases:

>100_bases
TACCGCCCTTCCAAAGCAAACGTTTGAAATGCGTTTTTGTTTTCCACCTCCTTTATGCACATCTGTTTGGATCTGCCAAA
TTGCGCACCTAGTAAAGCCT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MMKQSYVCRSCHTTYPVSRDLWKCLCGGLLDLDKQMPLLEPTAWESGPPTLWRFLDALPFEKDAKSWQNVTLGEGNTPLL
PVSADKPNVYVKVDYLMPTLSFKDRGAAVLIAKALELGATSVIADSSGNAGTAVSAYAARAGIACEVFCSNTVSPKKQAQ
MAAYNAKVHTIAGTREDVARAAQQKAANLEEGGFYASHVYNPYFYEGTKTYAYEIYEQLGDAPDTVIIPVGNGTLLLGAY
YGFSELLANRLIGKCPKIVAVQAQQCAPLAHAFATGEPSITPIVGQTTIAEGIAIAAPPRATQILEAVRNTGGTFITVSE
AQIAKARSALAKQGFDVEPTSAATYAALHVYRHCETETIVIPLCGSGTKASDHIAK

Sequences:

>Translated_376_residues
MMKQSYVCRSCHTTYPVSRDLWKCLCGGLLDLDKQMPLLEPTAWESGPPTLWRFLDALPFEKDAKSWQNVTLGEGNTPLL
PVSADKPNVYVKVDYLMPTLSFKDRGAAVLIAKALELGATSVIADSSGNAGTAVSAYAARAGIACEVFCSNTVSPKKQAQ
MAAYNAKVHTIAGTREDVARAAQQKAANLEEGGFYASHVYNPYFYEGTKTYAYEIYEQLGDAPDTVIIPVGNGTLLLGAY
YGFSELLANRLIGKCPKIVAVQAQQCAPLAHAFATGEPSITPIVGQTTIAEGIAIAAPPRATQILEAVRNTGGTFITVSE
AQIAKARSALAKQGFDVEPTSAATYAALHVYRHCETETIVIPLCGSGTKASDHIAK
>Mature_376_residues
MMKQSYVCRSCHTTYPVSRDLWKCLCGGLLDLDKQMPLLEPTAWESGPPTLWRFLDALPFEKDAKSWQNVTLGEGNTPLL
PVSADKPNVYVKVDYLMPTLSFKDRGAAVLIAKALELGATSVIADSSGNAGTAVSAYAARAGIACEVFCSNTVSPKKQAQ
MAAYNAKVHTIAGTREDVARAAQQKAANLEEGGFYASHVYNPYFYEGTKTYAYEIYEQLGDAPDTVIIPVGNGTLLLGAY
YGFSELLANRLIGKCPKIVAVQAQQCAPLAHAFATGEPSITPIVGQTTIAEGIAIAAPPRATQILEAVRNTGGTFITVSE
AQIAKARSALAKQGFDVEPTSAATYAALHVYRHCETETIVIPLCGSGTKASDHIAK

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. Does not catalyze the conversion of O-acetyl-L- homoserine into threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17508781, Length=286, Percent_Identity=27.6223776223776, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 40118; Mature: 40118

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKQSYVCRSCHTTYPVSRDLWKCLCGGLLDLDKQMPLLEPTAWESGPPTLWRFLDALPF
CCCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCC
EKDAKSWQNVTLGEGNTPLLPVSADKPNVYVKVDYLMPTLSFKDRGAAVLIAKALELGAT
CHHHHHHCCEEECCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCEEEEEHHHHHCCC
SVIADSSGNAGTAVSAYAARAGIACEVFCSNTVSPKKQAQMAAYNAKVHTIAGTREDVAR
EEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCEEEEECCCHHHHHH
AAQQKAANLEEGGFYASHVYNPYFYEGTKTYAYEIYEQLGDAPDTVIIPVGNGTLLLGAY
HHHHHHCCCCCCCEEHHHCCCCEEECCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEH
YGFSELLANRLIGKCPKIVAVQAQQCAPLAHAFATGEPSITPIVGQTTIAEGIAIAAPPR
HCHHHHHHHHHHHCCCCEEEECHHHCCHHHHHHHCCCCCCCEEECCHHHHCCEEEECCCH
ATQILEAVRNTGGTFITVSEAQIAKARSALAKQGFDVEPTSAATYAALHVYRHCETETIV
HHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEE
IPLCGSGTKASDHIAK
EEECCCCCCCCCCCCC
>Mature Secondary Structure
MMKQSYVCRSCHTTYPVSRDLWKCLCGGLLDLDKQMPLLEPTAWESGPPTLWRFLDALPF
CCCCHHHHHHCCCCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCC
EKDAKSWQNVTLGEGNTPLLPVSADKPNVYVKVDYLMPTLSFKDRGAAVLIAKALELGAT
CHHHHHHCCEEECCCCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCEEEEEHHHHHCCC
SVIADSSGNAGTAVSAYAARAGIACEVFCSNTVSPKKQAQMAAYNAKVHTIAGTREDVAR
EEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCEEEEECCCHHHHHH
AAQQKAANLEEGGFYASHVYNPYFYEGTKTYAYEIYEQLGDAPDTVIIPVGNGTLLLGAY
HHHHHHCCCCCCCEEHHHCCCCEEECCCHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEH
YGFSELLANRLIGKCPKIVAVQAQQCAPLAHAFATGEPSITPIVGQTTIAEGIAIAAPPR
HCHHHHHHHHHHHCCCCEEEECHHHCCHHHHHHHCCCCCCCEEECCHHHHCCEEEECCCH
ATQILEAVRNTGGTFITVSEAQIAKARSALAKQGFDVEPTSAATYAALHVYRHCETETIV
HHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEE
IPLCGSGTKASDHIAK
EEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]