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The map label for this gene is ubiE [C]

Identifier: 56964280

GI number: 56964280

Start: 2636706

End: 2637455

Strand: Direct

Name: ubiE [C]

Synonym: ABC2515

Alternate gene names: 56964280

Gene position: 2636706-2637455 (Clockwise)

Preceding gene: 56964279

Following gene: 56964287

Centisome position: 61.26

GC content: 40.53

Gene sequence:

>750_bases
ATGACTGAGTTTTTCTTTCAAAAGGAAGTAGCGGAAAAGTACGAAGCCTATAATGACATTTTGGAGCAACTATTAGGGTA
TCAATTTGTGTTTTCCCATTTTGACAAAGACGAGCGCCAGACCATTCTTGACTTTGGCTGTGGGCCAGGCAAAATCGCAA
CACGCTTTGCTGAGTTGTTTTCAGCGACCGTTATTGCAGTCGACCAATCGGCAGAAATGATTCAGCTTGCTTCCAAGAAA
CACAACCATAAAAACGTGCATTATCGTTTAGTGAAAGACCCAAAACTCGCTTTTTTAGATGACAACTCCATTGATGGTGC
TTTTTCATGTTTCGTTTTCATTACGATTGGGGATGAAGCAGTACTAAACAACATTTTGCAAGAAATATACCGTGTATTAA
AACCAGGTGCTCCATTTGTGCTGTTAGATACCAATCCCAATTCCACAGGTCATGTTTTTTCCACATGCCGTATCGGCGAA
AAAGGCAAAACCTACAAACGGGGCGATATCATTCAAAAAGAATTGCGTTGGGGCGGAAATCAGTTGCTAATTGAAGATTA
CCATTGGCCAGAAAAAACGTATGAAACATGGCTCGTTAACAACGGCTTTATTGAAATCGAAACACAACAACCGACGCTAC
AAAACGTTGCCAATAAGACGATTCGACGTGTGGAAGATGAGTACGGCCTAAAATGGAAAGATGAAAAAACCGTTCCTCCC
TTTATTCTTTTTAAAGGGATTAAAGGATAG

Upstream 100 bases:

>100_bases
TTAAGCCTGGTTTTTTTATTTTTACCGGTTTCCACCTTCTGTCATTGCACACTCTTTTAATTCCAAGCATATAACTATGT
TTACTAGGAGGTGTAGAGGG

Downstream 100 bases:

>100_bases
GATCGTTAATTGGAAAACCGTTTAGCCCTAACAGATTGGCAACCTATTGTACGATTAAAGAATAATATTTTTTGATGAAT
GCAAAACCATCTTATGCCAA

Product: S-adenosylmethionine (SAM)-dependent methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase UbiE/COQ5 Family; Methyltransferase UbiE/COQ5 Family Protein; SAM-Dependent Methyltransferase; Methyltransferase Protein; UbiE/COQ5 Family Methlytransferase

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTEFFFQKEVAEKYEAYNDILEQLLGYQFVFSHFDKDERQTILDFGCGPGKIATRFAELFSATVIAVDQSAEMIQLASKK
HNHKNVHYRLVKDPKLAFLDDNSIDGAFSCFVFITIGDEAVLNNILQEIYRVLKPGAPFVLLDTNPNSTGHVFSTCRIGE
KGKTYKRGDIIQKELRWGGNQLLIEDYHWPEKTYETWLVNNGFIEIETQQPTLQNVANKTIRRVEDEYGLKWKDEKTVPP
FILFKGIKG

Sequences:

>Translated_249_residues
MTEFFFQKEVAEKYEAYNDILEQLLGYQFVFSHFDKDERQTILDFGCGPGKIATRFAELFSATVIAVDQSAEMIQLASKK
HNHKNVHYRLVKDPKLAFLDDNSIDGAFSCFVFITIGDEAVLNNILQEIYRVLKPGAPFVLLDTNPNSTGHVFSTCRIGE
KGKTYKRGDIIQKELRWGGNQLLIEDYHWPEKTYETWLVNNGFIEIETQQPTLQNVANKTIRRVEDEYGLKWKDEKTVPP
FILFKGIKG
>Mature_248_residues
TEFFFQKEVAEKYEAYNDILEQLLGYQFVFSHFDKDERQTILDFGCGPGKIATRFAELFSATVIAVDQSAEMIQLASKKH
NHKNVHYRLVKDPKLAFLDDNSIDGAFSCFVFITIGDEAVLNNILQEIYRVLKPGAPFVLLDTNPNSTGHVFSTCRIGEK
GKTYKRGDIIQKELRWGGNQLLIEDYHWPEKTYETWLVNNGFIEIETQQPTLQNVANKTIRRVEDEYGLKWKDEKTVPPF
ILFKGIKG

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28697; Mature: 28566

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFFFQKEVAEKYEAYNDILEQLLGYQFVFSHFDKDERQTILDFGCGPGKIATRFAELF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
SATVIAVDQSAEMIQLASKKHNHKNVHYRLVKDPKLAFLDDNSIDGAFSCFVFITIGDEA
HHEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCEEEEEEEEEECCHH
VLNNILQEIYRVLKPGAPFVLLDTNPNSTGHVFSTCRIGEKGKTYKRGDIIQKELRWGGN
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCC
QLLIEDYHWPEKTYETWLVNNGFIEIETQQPTLQNVANKTIRRVEDEYGLKWKDEKTVPP
EEEEECCCCCCHHHHEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHCCEECCCCCCCC
FILFKGIKG
EEEEECCCC
>Mature Secondary Structure 
TEFFFQKEVAEKYEAYNDILEQLLGYQFVFSHFDKDERQTILDFGCGPGKIATRFAELF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHH
SATVIAVDQSAEMIQLASKKHNHKNVHYRLVKDPKLAFLDDNSIDGAFSCFVFITIGDEA
HHEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCEEEEEEEEEECCHH
VLNNILQEIYRVLKPGAPFVLLDTNPNSTGHVFSTCRIGEKGKTYKRGDIIQKELRWGGN
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCC
QLLIEDYHWPEKTYETWLVNNGFIEIETQQPTLQNVANKTIRRVEDEYGLKWKDEKTVPP
EEEEECCCCCCHHHHEEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHCCEECCCCCCCC
FILFKGIKG
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA