Click here to switch to the map view.

The map label for this gene is glvR [H]

Identifier: 56963850

GI number: 56963850

Start: 2205154

End: 2205891

Strand: Direct

Name: glvR [H]

Synonym: ABC2085

Alternate gene names: 56963850

Gene position: 2205154-2205891 (Clockwise)

Preceding gene: 56963849

Following gene: 56963853

Centisome position: 51.24

GC content: 35.09

Gene sequence:

>738_bases
ATGTTTGATATTTTGAAGAACTATGAAGAACTGACCGTAAGTGAAAAGAGAGTCCTGAGCTACATCATGGAAAATCAAGA
TCAAATTCCCCATATTAAAATTAATGATTTGGCAGAGGCAACGTTTGTTTCAAAAACGGTCATTATCAATTTGGCGCAGA
AATTAGATTTTTCCGGTTTCCGAGAAATGAAATATTATATCAGCCAGAGAATCATTGAAAAAATGTCTGCACAGGAAACA
AGCACGGTCCTGTATCGGGAGATTTTAAAACAGTCTATGGATAAGACATTCTCCCTTGTCACGGAAGAGCAGCTGCAAAA
AACAGCTGCCAAAATTAAAGCTGCGAAAAATGTATTTATTATGGCGAGAGGAACAAGCAAAGCTGTCGGTTATTATTTGG
AGCATCTCTTATTGACAATTGGCATCCAATGTATCTTTATAAAGGATTACAATTTATCGGAAGTGTTTACGGATTTTGTG
GCCGAAGAGGATATTGTCATCTTTATTTCCTTATCGGGAGACACGAAAAAAATTATTAATACTGCGAAAAAAATTCATTT
AAAAAAAGCCGAAATCATTAGTATCACTTCATTCAAAACAAATGAATTGACCCGGTATACGACGAACAACCTATTTTGTT
ATACCGACAAAACGAACACAAGCAAAAATGACACCATTTCAAGAACTGGTTTTTTTCTTACGATTGACTTGTTGGTTGAT
AAATTGGCCAACCTTTAA

Upstream 100 bases:

>100_bases
AAAAACATACAAATACAAGGGCTCTGTTAAAATGGTCCCATCCGGTGTACTATATTTACAATATGTATTGCTTTTAGAAC
TTTGATTGGATGGAGAGAAT

Downstream 100 bases:

>100_bases
ATCGCGTAGGCAGTGGTGCTAGTAAAAACGACAAAAATAACGCTCTTCCATAAAAGAAGAACGCTATTTGTCGTTCATTA
ATGGCTGTAGTTTTCGCGGA

Product: transcriptional regulator

Products: NA

Alternate protein names: Glv operon regulatory protein [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MFDILKNYEELTVSEKRVLSYIMENQDQIPHIKINDLAEATFVSKTVIINLAQKLDFSGFREMKYYISQRIIEKMSAQET
STVLYREILKQSMDKTFSLVTEEQLQKTAAKIKAAKNVFIMARGTSKAVGYYLEHLLLTIGIQCIFIKDYNLSEVFTDFV
AEEDIVIFISLSGDTKKIINTAKKIHLKKAEIISITSFKTNELTRYTTNNLFCYTDKTNTSKNDTISRTGFFLTIDLLVD
KLANL

Sequences:

>Translated_245_residues
MFDILKNYEELTVSEKRVLSYIMENQDQIPHIKINDLAEATFVSKTVIINLAQKLDFSGFREMKYYISQRIIEKMSAQET
STVLYREILKQSMDKTFSLVTEEQLQKTAAKIKAAKNVFIMARGTSKAVGYYLEHLLLTIGIQCIFIKDYNLSEVFTDFV
AEEDIVIFISLSGDTKKIINTAKKIHLKKAEIISITSFKTNELTRYTTNNLFCYTDKTNTSKNDTISRTGFFLTIDLLVD
KLANL
>Mature_245_residues
MFDILKNYEELTVSEKRVLSYIMENQDQIPHIKINDLAEATFVSKTVIINLAQKLDFSGFREMKYYISQRIIEKMSAQET
STVLYREILKQSMDKTFSLVTEEQLQKTAAKIKAAKNVFIMARGTSKAVGYYLEHLLLTIGIQCIFIKDYNLSEVFTDFV
AEEDIVIFISLSGDTKKIINTAKKIHLKKAEIISITSFKTNELTRYTTNNLFCYTDKTNTSKNDTISRTGFFLTIDLLVD
KLANL

Specific function: Positive regulator of the glv operon expression, which consists of glvA, glvR and glvC [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI87082130, Length=236, Percent_Identity=20.3389830508475, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI87082369, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788767, Length=253, Percent_Identity=23.7154150197628, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 28156; Mature: 28156

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDILKNYEELTVSEKRVLSYIMENQDQIPHIKINDLAEATFVSKTVIINLAQKLDFSGF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHH
REMKYYISQRIIEKMSAQETSTVLYREILKQSMDKTFSLVTEEQLQKTAAKIKAAKNVFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
MARGTSKAVGYYLEHLLLTIGIQCIFIKDYNLSEVFTDFVAEEDIVIFISLSGDTKKIIN
EECCCCHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCHHHHHH
TAKKIHLKKAEIISITSFKTNELTRYTTNNLFCYTDKTNTSKNDTISRTGFFLTIDLLVD
HHHHHHCCHHHEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCEECCCHHEEHHHHHH
KLANL
HHHCC
>Mature Secondary Structure
MFDILKNYEELTVSEKRVLSYIMENQDQIPHIKINDLAEATFVSKTVIINLAQKLDFSGF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCHH
REMKYYISQRIIEKMSAQETSTVLYREILKQSMDKTFSLVTEEQLQKTAAKIKAAKNVFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
MARGTSKAVGYYLEHLLLTIGIQCIFIKDYNLSEVFTDFVAEEDIVIFISLSGDTKKIIN
EECCCCHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHCCCCEEEEEEECCCHHHHHH
TAKKIHLKKAEIISITSFKTNELTRYTTNNLFCYTDKTNTSKNDTISRTGFFLTIDLLVD
HHHHHHCCHHHEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCCEECCCHHEEHHHHHH
KLANL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377; 11489864 [H]