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The map label for this gene is 56963702

Identifier: 56963702

GI number: 56963702

Start: 2051908

End: 2052489

Strand: Direct

Name: 56963702

Synonym: ABC1937

Alternate gene names: NA

Gene position: 2051908-2052489 (Clockwise)

Preceding gene: 56963701

Following gene: 56963706

Centisome position: 47.68

GC content: 45.02

Gene sequence:

>582_bases
TTGGAAATACAATCGTTAGCGGTGTTTTGTGGGTCTAGTGCTGGCAAAGATCCAGTTTATATCGAACAGGCGACAGCCTT
TGGCAAACTCCTCGCCGAAAATGAAATAACCCTTGTTTATGGGGGAGCCCAAGTAGGTTGTATGGGGGCCGTTGCCAATG
CTTGCTTGCAAGCAGGGGGACGTGTCATAGGTGTAATTCCCAAAAAACTACAAAATGTAGAGATTGCACATGACAAATTG
TCTGAGCTATATGTTGTCGATACGATGCACGAGCGGAAAGCGCTTATGGCTGAGCATGCAGATGCCTTTGTTGCCTTGCC
AGGAGGAGCGGGAACGCTTGAAGAATGGTTTGAAGTGTTTACTTGGATCCAGCTAGATTACCATCAAAAGCCATGCAGTT
TGTTAAACGTAGCCGATTTCTTTAATCCGCTTTTGGCCATGCTTGATCATACGATTGAACAAGGGTTTATGGCTGAAGCG
TATCGAGATTTGTTTATCGTCGAGAAAGAACCGCAAGCGTTATTGGAACGGTTAAAAGGGTATCGTCACAAGCATGTATC
AAAATGGACAGAGAATGGATGA

Upstream 100 bases:

>100_bases
ATGCAGCCACCACCCATGGCGGTTTATTGATGGGAACAGTCGTGCTGTATCGGCTTATCGGCCTTGATCGAATGTGAGGA
CAGAGAAAGGAATGGGAGAA

Downstream 100 bases:

>100_bases
AAGAGAGGGGCGGATGCTCCTCTTTTTTTGAGGCGCCATCAAAGAGAAAACAAGCCCTCAATATGAGGGCTTGTTTTTAA
CGGAGGCTTCCAGCGCCAAC

Product: lysine decarboxylase

Products: cadaverine; CO2

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MEIQSLAVFCGSSAGKDPVYIEQATAFGKLLAENEITLVYGGAQVGCMGAVANACLQAGGRVIGVIPKKLQNVEIAHDKL
SELYVVDTMHERKALMAEHADAFVALPGGAGTLEEWFEVFTWIQLDYHQKPCSLLNVADFFNPLLAMLDHTIEQGFMAEA
YRDLFIVEKEPQALLERLKGYRHKHVSKWTENG

Sequences:

>Translated_193_residues
MEIQSLAVFCGSSAGKDPVYIEQATAFGKLLAENEITLVYGGAQVGCMGAVANACLQAGGRVIGVIPKKLQNVEIAHDKL
SELYVVDTMHERKALMAEHADAFVALPGGAGTLEEWFEVFTWIQLDYHQKPCSLLNVADFFNPLLAMLDHTIEQGFMAEA
YRDLFIVEKEPQALLERLKGYRHKHVSKWTENG
>Mature_193_residues
MEIQSLAVFCGSSAGKDPVYIEQATAFGKLLAENEITLVYGGAQVGCMGAVANACLQAGGRVIGVIPKKLQNVEIAHDKL
SELYVVDTMHERKALMAEHADAFVALPGGAGTLEEWFEVFTWIQLDYHQKPCSLLNVADFFNPLLAMLDHTIEQGFMAEA
YRDLFIVEKEPQALLERLKGYRHKHVSKWTENG

Specific function: Unknown

COG id: COG1611

COG function: function code R; Predicted Rossmann fold nucleotide-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LOG family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322406, Length=204, Percent_Identity=35.7843137254902, Blast_Score=121, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005269 [H]

Pfam domain/function: PF03641 Lysine_decarbox [H]

EC number: 4.1.1.18

Molecular weight: Translated: 21356; Mature: 21356

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIQSLAVFCGSSAGKDPVYIEQATAFGKLLAENEITLVYGGAQVGCMGAVANACLQAGG
CCHHHHHHEECCCCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCC
RVIGVIPKKLQNVEIAHDKLSELYVVDTMHERKALMAEHADAFVALPGGAGTLEEWFEVF
CEEEECCHHHCCCHHHHHHHHHEEEEHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
TWIQLDYHQKPCSLLNVADFFNPLLAMLDHTIEQGFMAEAYRDLFIVEKEPQALLERLKG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHH
YRHKHVSKWTENG
HHHHHHHHHCCCC
>Mature Secondary Structure
MEIQSLAVFCGSSAGKDPVYIEQATAFGKLLAENEITLVYGGAQVGCMGAVANACLQAGG
CCHHHHHHEECCCCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCC
RVIGVIPKKLQNVEIAHDKLSELYVVDTMHERKALMAEHADAFVALPGGAGTLEEWFEVF
CEEEECCHHHCCCHHHHHHHHHEEEEHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
TWIQLDYHQKPCSLLNVADFFNPLLAMLDHTIEQGFMAEAYRDLFIVEKEPQALLERLKG
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHH
YRHKHVSKWTENG
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-lysine

Specific reaction: L-lysine = cadaverine + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 2116366 [H]