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The map label for this gene is trpD

Identifier: 56963661

GI number: 56963661

Start: 2013260

End: 2014285

Strand: Direct

Name: trpD

Synonym: ABC1896

Alternate gene names: 56963661

Gene position: 2013260-2014285 (Clockwise)

Preceding gene: 56963660

Following gene: 56963662

Centisome position: 46.78

GC content: 51.75

Gene sequence:

>1026_bases
ATGATGAAGCACGTGCTGAACAAATGTTTAATGGGCGAATCCTTGTCTGTACAAGAAGCAGAGCAAGTGATGGAACAAAT
CATGTCAGGGCGCGCAACCGCCAGCCAAGTGGCGAGCCTCATTACGATGATGCGCGTTCGCGGCGAGACTGCGGAGGAAA
TTCTCGGCTTTGCCAAAGGGATGCGCGCTTATGCGCGCAAATTCCCTGCTGTCATTGAGGGGACGATTGATACGTGCGGC
ACAGGAGGAGATGGACTTGGAACGTTTAACATCTCGACTGCGTCAGCGCTCGTTTTGGCGTCGCTCGGTGTCCCTGTCGC
CAAACACGGCAATCGCTCTGTCTCTTCCAAAAGCGGCAGTGCTGATGTGTTGGAAGAGCTCGGCATCAACATTCAAGCTT
CCGTTGAAGAAGCTTGCCAAATGCTTGAAACAACAAACTTGTGCTTTTTATTTGCGCCGCTGTACCACCAGTCAATGCGC
CACGTCGCTGGCCCACGGAAAGAAATTGGCTTCCGTACCATTTTTAATTTGCTAGGCCCGCTTACGAACCCAGCCGGTGC
CCGTTACCAGCTTCTCGGCGTTTACGATGAAGCGGCCGCTTTGAAAATGGGAGAAGCATTGCGCCAGCTTGGTAGCGAGC
ACAGCCTTTTAGTTACAGGCGCTGATGGCCTTGATGAATGTGCCATTCATGGCGACACACACGTAGTAGAAGTGAAAGAT
GGTAGGTGCGAAACGTATCGGTTCTCACCTGACGACGTAGGCTTGCCGCTTGGAAATCTTGCTGATATCCAAGTAGATAC
GCCCGCTGAAAGTGCTGCGTTAATCCGCGCGATTTTTTCAGGCGACGGGCCACAGGCAGCGAAAAACATTGTTGCTTTAA
ATGCTGGAGCAGCGTTGTACGCCTGTGGAAATGCCAGTCACATTGCTGAAGGCGTTCACTATGCCAGCAAAGCGATAGAG
AGCAAACGAGTGTTTCGCTATTTGCAATCATTGCAACAACAGGGAAGGGGAATCAAGCATGCTTGA

Upstream 100 bases:

>100_bases
ACCCGGAAAAAGAATACGAAGAAACATTAAACAAAGCAAAGGCACTTATTCATGCGATTGAACAGACAGAAGCATTGTTT
GCAAAGGCGGTGCGTTTGTC

Downstream 100 bases:

>100_bases
GAAAATTTTGGCGACAAAACGAGAGGAAATCAGCCAACTCCAGTTGCCTGAAAAGCAGTATTTTCCAAAAAAAAGCCTGA
AAGCGTCCTTACAAAAAACA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MMKHVLNKCLMGESLSVQEAEQVMEQIMSGRATASQVASLITMMRVRGETAEEILGFAKGMRAYARKFPAVIEGTIDTCG
TGGDGLGTFNISTASALVLASLGVPVAKHGNRSVSSKSGSADVLEELGINIQASVEEACQMLETTNLCFLFAPLYHQSMR
HVAGPRKEIGFRTIFNLLGPLTNPAGARYQLLGVYDEAAALKMGEALRQLGSEHSLLVTGADGLDECAIHGDTHVVEVKD
GRCETYRFSPDDVGLPLGNLADIQVDTPAESAALIRAIFSGDGPQAAKNIVALNAGAALYACGNASHIAEGVHYASKAIE
SKRVFRYLQSLQQQGRGIKHA

Sequences:

>Translated_341_residues
MMKHVLNKCLMGESLSVQEAEQVMEQIMSGRATASQVASLITMMRVRGETAEEILGFAKGMRAYARKFPAVIEGTIDTCG
TGGDGLGTFNISTASALVLASLGVPVAKHGNRSVSSKSGSADVLEELGINIQASVEEACQMLETTNLCFLFAPLYHQSMR
HVAGPRKEIGFRTIFNLLGPLTNPAGARYQLLGVYDEAAALKMGEALRQLGSEHSLLVTGADGLDECAIHGDTHVVEVKD
GRCETYRFSPDDVGLPLGNLADIQVDTPAESAALIRAIFSGDGPQAAKNIVALNAGAALYACGNASHIAEGVHYASKAIE
SKRVFRYLQSLQQQGRGIKHA
>Mature_341_residues
MMKHVLNKCLMGESLSVQEAEQVMEQIMSGRATASQVASLITMMRVRGETAEEILGFAKGMRAYARKFPAVIEGTIDTCG
TGGDGLGTFNISTASALVLASLGVPVAKHGNRSVSSKSGSADVLEELGINIQASVEEACQMLETTNLCFLFAPLYHQSMR
HVAGPRKEIGFRTIFNLLGPLTNPAGARYQLLGVYDEAAALKMGEALRQLGSEHSLLVTGADGLDECAIHGDTHVVEVKD
GRCETYRFSPDDVGLPLGNLADIQVDTPAESAALIRAIFSGDGPQAAKNIVALNAGAALYACGNASHIAEGVHYASKAIE
SKRVFRYLQSLQQQGRGIKHA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=282, Percent_Identity=39.3617021276596, Blast_Score=192, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6320561, Length=269, Percent_Identity=32.3420074349442, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_BACSK (Q5WGS4)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175392.1
- ProteinModelPortal:   Q5WGS4
- SMR:   Q5WGS4
- STRING:   Q5WGS4
- EnsemblBacteria:   EBBACT00000049083
- GeneID:   3203563
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1896
- NMPDR:   fig|66692.3.peg.1940
- eggNOG:   COG0547
- GeneTree:   EBGT00050000002544
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   BCLA66692:ABC1896-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36193; Mature: 36193

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKHVLNKCLMGESLSVQEAEQVMEQIMSGRATASQVASLITMMRVRGETAEEILGFAKG
CHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MRAYARKFPAVIEGTIDTCGTGGDGLGTFNISTASALVLASLGVPVAKHGNRSVSSKSGS
HHHHHHHCCHHHCCCHHCCCCCCCCCEEEECHHHHHHHHHHHCCCHHCCCCCCCCCCCCC
ADVLEELGINIQASVEEACQMLETTNLCFLFAPLYHQSMRHVAGPRKEIGFRTIFNLLGP
HHHHHHCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
LTNPAGARYQLLGVYDEAAALKMGEALRQLGSEHSLLVTGADGLDECAIHGDTHVVEVKD
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHEECCCCEEEEECC
GRCETYRFSPDDVGLPLGNLADIQVDTPAESAALIRAIFSGDGPQAAKNIVALNAGAALY
CCCEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHEEEEECCCEEE
ACGNASHIAEGVHYASKAIESKRVFRYLQSLQQQGRGIKHA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMKHVLNKCLMGESLSVQEAEQVMEQIMSGRATASQVASLITMMRVRGETAEEILGFAKG
CHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
MRAYARKFPAVIEGTIDTCGTGGDGLGTFNISTASALVLASLGVPVAKHGNRSVSSKSGS
HHHHHHHCCHHHCCCHHCCCCCCCCCEEEECHHHHHHHHHHHCCCHHCCCCCCCCCCCCC
ADVLEELGINIQASVEEACQMLETTNLCFLFAPLYHQSMRHVAGPRKEIGFRTIFNLLGP
HHHHHHCCCCEEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
LTNPAGARYQLLGVYDEAAALKMGEALRQLGSEHSLLVTGADGLDECAIHGDTHVVEVKD
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHEECCCCEEEEECC
GRCETYRFSPDDVGLPLGNLADIQVDTPAESAALIRAIFSGDGPQAAKNIVALNAGAALY
CCCEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHEEEEECCCEEE
ACGNASHIAEGVHYASKAIESKRVFRYLQSLQQQGRGIKHA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA