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The map label for this gene is yycG [H]

Identifier: 56963625

GI number: 56963625

Start: 1976246

End: 1977688

Strand: Direct

Name: yycG [H]

Synonym: ABC1860

Alternate gene names: 56963625

Gene position: 1976246-1977688 (Clockwise)

Preceding gene: 56963624

Following gene: 56963626

Centisome position: 45.92

GC content: 45.32

Gene sequence:

>1443_bases
ATGAAGCTTAGGGGGCAGTTAAACTTGCTCTTGCTCGCAACCGCGCTTGTCCCGTTTATCGCGACAAGCTTATTTTCATA
CCAACTAAACCGTGTGGCGAAAGAAGAGTCAAGTAACCATTTAGAATCGATGATTGTCGCTAAAAGCATAAGCCGAACGC
TAAATCAGAATGCACAAATGTTTGATGGCTCGGCAAAGGAGCTTGGCCGCTTGGCGCTCAAACAACATGAAAACGTCCAG
TTAGGTCTTTATTCAAAGGATCGGGCTTTGCAATTCCAAAGCTCCTCTGAGGAAGGGGGATTTGCCACCCACCTTACGCC
AGAGGCCATGTTCAGCAATTTGTATAGTTGGCAATCAAGTGATTCGGCCTACATTTACAAGGAGCCGATTTTTTTGCAAG
ACCAAATTGCAGGCTACTTTGAGCTTCACTTTGACAAAAGCGGCATACGCAAGGAAACGAAGGAAGTCTACATGCTGACG
ATCCTGTTTTTCCTTATAACGGTAGGTATCACGCTTTTCATTGTCCAGCACTGGTTTAAACGGAATATGCTCGTTCCTTT
TGCTTGGATGAAAGCGGAAATGGACGAAGTGGCTTATGGGAAACAAAATCGTACGACTCCAGTGAAGCGTGGCCGCACAG
AAGTTGGCCAACTGATGGACAATTTTGCGAACATGGCAGCGCATTTGCGTGCAATTGATGCCCAAAAACAAAGTGATGAC
GAAGATCGCAAAAAGCTGATTGCGGCGATTTCACATGATTTACGGACGCCTTTAACATCGATACGTGCGTATGCGGAAGG
GATGAACGCCCACCCTGACAAAAGGGAAGAGTACAGCAAGGTTATTTTAGCAAAGACTGAGTATATGCAACGATTGATTG
AAGATTTGCTGATTTTCTCCCAAGTTCATTCAACGAGCTTTAGTTTGTCGTTAAAAAAAGTCGATGCAGAAGAGCTTGTC
GAATTGTTGTTTGATGGCTACGACCTTGAAAAAGAGCAGCTAAGGTTAAGTACGAGCATGGAGATAGAGCCGGCTGAAGT
CGATGCAGATGCAGGCCGCCTTGTTCAAGTCATGGACAATTTGGTTACCAATGCCATTTGCTATTCGCCTGAAGGAGGAG
CGATTTCCTTGTATGCAACAAACAAGCAGTCTTGTTTGCCACCATTCGTGGAACGGACAAATGAACAGCGACTCTATATT
TTTGTTAAAGATGAAGGACAAGGCATCCCAAGTGGCGTACAACGCCAGCTCTTTGACCCGTTTTTTCAAGTAGAACAGGC
GAGAAGCCAAACAAACGACAAGGGGGTAGGCTTAGGACTGTCTATTTGCCGGGAGCTGATTCATCAACATGGAGGCACAA
TTGATGTCTATTCGTCGCCACCACATGGAAGTACGTTTTTCTTTTCCATTCCGTGCATAAAAACTGAGGGGGGAAATGAA
TGA

Upstream 100 bases:

>100_bases
TGAAAAATGTCAGACACAAATTAAAAGACGGGACGAAGCATCCGAAATACATAGAAACGGTATGGGGCGTTGGTTATAAA
TTTATAGGACTTGGGAACCG

Downstream 100 bases:

>100_bases
AACGGCAACCGCTTTTTTTAGCGGCTATAACAGGGTTGTTGTTTACAGGCGGGTGCAGCTTTATGAGCATCAATGCTGAA
GAGGTGCTAGAACAAGCCCT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MKLRGQLNLLLLATALVPFIATSLFSYQLNRVAKEESSNHLESMIVAKSISRTLNQNAQMFDGSAKELGRLALKQHENVQ
LGLYSKDRALQFQSSSEEGGFATHLTPEAMFSNLYSWQSSDSAYIYKEPIFLQDQIAGYFELHFDKSGIRKETKEVYMLT
ILFFLITVGITLFIVQHWFKRNMLVPFAWMKAEMDEVAYGKQNRTTPVKRGRTEVGQLMDNFANMAAHLRAIDAQKQSDD
EDRKKLIAAISHDLRTPLTSIRAYAEGMNAHPDKREEYSKVILAKTEYMQRLIEDLLIFSQVHSTSFSLSLKKVDAEELV
ELLFDGYDLEKEQLRLSTSMEIEPAEVDADAGRLVQVMDNLVTNAICYSPEGGAISLYATNKQSCLPPFVERTNEQRLYI
FVKDEGQGIPSGVQRQLFDPFFQVEQARSQTNDKGVGLGLSICRELIHQHGGTIDVYSSPPHGSTFFFSIPCIKTEGGNE

Sequences:

>Translated_480_residues
MKLRGQLNLLLLATALVPFIATSLFSYQLNRVAKEESSNHLESMIVAKSISRTLNQNAQMFDGSAKELGRLALKQHENVQ
LGLYSKDRALQFQSSSEEGGFATHLTPEAMFSNLYSWQSSDSAYIYKEPIFLQDQIAGYFELHFDKSGIRKETKEVYMLT
ILFFLITVGITLFIVQHWFKRNMLVPFAWMKAEMDEVAYGKQNRTTPVKRGRTEVGQLMDNFANMAAHLRAIDAQKQSDD
EDRKKLIAAISHDLRTPLTSIRAYAEGMNAHPDKREEYSKVILAKTEYMQRLIEDLLIFSQVHSTSFSLSLKKVDAEELV
ELLFDGYDLEKEQLRLSTSMEIEPAEVDADAGRLVQVMDNLVTNAICYSPEGGAISLYATNKQSCLPPFVERTNEQRLYI
FVKDEGQGIPSGVQRQLFDPFFQVEQARSQTNDKGVGLGLSICRELIHQHGGTIDVYSSPPHGSTFFFSIPCIKTEGGNE
>Mature_480_residues
MKLRGQLNLLLLATALVPFIATSLFSYQLNRVAKEESSNHLESMIVAKSISRTLNQNAQMFDGSAKELGRLALKQHENVQ
LGLYSKDRALQFQSSSEEGGFATHLTPEAMFSNLYSWQSSDSAYIYKEPIFLQDQIAGYFELHFDKSGIRKETKEVYMLT
ILFFLITVGITLFIVQHWFKRNMLVPFAWMKAEMDEVAYGKQNRTTPVKRGRTEVGQLMDNFANMAAHLRAIDAQKQSDD
EDRKKLIAAISHDLRTPLTSIRAYAEGMNAHPDKREEYSKVILAKTEYMQRLIEDLLIFSQVHSTSFSLSLKKVDAEELV
ELLFDGYDLEKEQLRLSTSMEIEPAEVDADAGRLVQVMDNLVTNAICYSPEGGAISLYATNKQSCLPPFVERTNEQRLYI
FVKDEGQGIPSGVQRQLFDPFFQVEQARSQTNDKGVGLGLSICRELIHQHGGTIDVYSSPPHGSTFFFSIPCIKTEGGNE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=236, Percent_Identity=31.3559322033898, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=30.7053941908714, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788549, Length=235, Percent_Identity=28.936170212766, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=29.7071129707113, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082128, Length=322, Percent_Identity=24.223602484472, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI87081816, Length=439, Percent_Identity=23.2346241457859, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789149, Length=388, Percent_Identity=26.8041237113402, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.9915966386555, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=295, Percent_Identity=24.7457627118644, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=33.7552742616034, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790346, Length=291, Percent_Identity=25.4295532646048, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=236, Percent_Identity=28.8135593220339, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=26.0330578512397, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787894, Length=316, Percent_Identity=27.2151898734177, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=24.5614035087719, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790861, Length=297, Percent_Identity=24.9158249158249, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54264; Mature: 54264

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRGQLNLLLLATALVPFIATSLFSYQLNRVAKEESSNHLESMIVAKSISRTLNQNAQM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FDGSAKELGRLALKQHENVQLGLYSKDRALQFQSSSEEGGFATHLTPEAMFSNLYSWQSS
CCCCHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCEEECCCHHHHHHHHHHCCCC
DSAYIYKEPIFLQDQIAGYFELHFDKSGIRKETKEVYMLTILFFLITVGITLFIVQHWFK
CCEEEEECCEEEHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNMLVPFAWMKAEMDEVAYGKQNRTTPVKRGRTEVGQLMDNFANMAAHLRAIDAQKQSDD
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EDRKKLIAAISHDLRTPLTSIRAYAEGMNAHPDKREEYSKVILAKTEYMQRLIEDLLIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVHSTSFSLSLKKVDAEELVELLFDGYDLEKEQLRLSTSMEIEPAEVDADAGRLVQVMDN
HHHCCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
LVTNAICYSPEGGAISLYATNKQSCLPPFVERTNEQRLYIFVKDEGQGIPSGVQRQLFDP
HHHHHEEECCCCCEEEEEECCCCCCCCHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHH
FFQVEQARSQTNDKGVGLGLSICRELIHQHGGTIDVYSSPPHGSTFFFSIPCIKTEGGNE
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECEEECCCCCC
>Mature Secondary Structure
MKLRGQLNLLLLATALVPFIATSLFSYQLNRVAKEESSNHLESMIVAKSISRTLNQNAQM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
FDGSAKELGRLALKQHENVQLGLYSKDRALQFQSSSEEGGFATHLTPEAMFSNLYSWQSS
CCCCHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCCCEEECCCHHHHHHHHHHCCCC
DSAYIYKEPIFLQDQIAGYFELHFDKSGIRKETKEVYMLTILFFLITVGITLFIVQHWFK
CCEEEEECCEEEHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNMLVPFAWMKAEMDEVAYGKQNRTTPVKRGRTEVGQLMDNFANMAAHLRAIDAQKQSDD
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EDRKKLIAAISHDLRTPLTSIRAYAEGMNAHPDKREEYSKVILAKTEYMQRLIEDLLIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVHSTSFSLSLKKVDAEELVELLFDGYDLEKEQLRLSTSMEIEPAEVDADAGRLVQVMDN
HHHCCCEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
LVTNAICYSPEGGAISLYATNKQSCLPPFVERTNEQRLYIFVKDEGQGIPSGVQRQLFDP
HHHHHEEECCCCCEEEEEECCCCCCCCHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHH
FFQVEQARSQTNDKGVGLGLSICRELIHQHGGTIDVYSSPPHGSTFFFSIPCIKTEGGNE
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCEEEEEECEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]