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The map label for this gene is yhaA [H]

Identifier: 56963620

GI number: 56963620

Start: 1971668

End: 1972855

Strand: Direct

Name: yhaA [H]

Synonym: ABC1855

Alternate gene names: 56963620

Gene position: 1971668-1972855 (Clockwise)

Preceding gene: 56963619

Following gene: 56963621

Centisome position: 45.81

GC content: 47.22

Gene sequence:

>1188_bases
GTGCAAGAGTCGTTGTTTAAAAAACTTGAATCACTTTACCCAGAAATGGTGGAATTGCGCCGGGATTTTCATGCTGAGCC
TGAACTGGCCTTTGAAGAAGAAGTAACACCAAGAAAAATTGCTTCCTATTTGCAAAATCTTGGTATTGACGTGCGCACAC
AAGTAGGGGGACGTGGTGTCGTCGGGACGATCAAAGGCAAAAAACCAGGCAAAACAGTAGCATTGCGGGCTGATTTTGAT
GCGTTGCCAATTCAAGAAGAAACAGGGCTGCCGTTTGCTTCGAAAATTCCTGGGAAAATGCATGCTTGTGGCCATGATGG
CCATACCGCTACATTGCTCGTATTGGCAAAAGCGCTTGTGGCGATGCGTGATGAGTTAGAAGGGACGGTTGTTCTCATCC
ATCAATTTGCAGAAGAATTTGCCCCAGGCGGTGCGATTGCAATGATTGAAGATGGTTGTTTAGATGGGGTGGACGCCATT
TTTGGCACCCATTTGTGGAGCCCTCTTCCTTATGGGGAAGTTGGCTATTCATATGACCGTTTGATGGCTGCTTCAGACCG
CTTTGAAGTAAATATACAAGGAAAAGGCGGGCACGGAGCTCTTCCCCATGAAACAGTCGATGCTGTCATGGTCGGCTCGT
CTATAGCGCTGATGCTCCAACAGCTAGTGAGCCGCAATGTCAACCCTTTAGAACCGGCAGTTGTCACAATCGCTTCTTTC
CACGCCGGAGGTGCTTTCAACGTCATTAGCGATACGGCGAAATTAGAAGGGACGGTAAGGACGTTTAGTGAAAGCGTACA
AGACCAATTAATTGCCCGTATGGAAGAAACGATCAAAGGGGTATGCGAGGCGAGCGGAGCGACTTATTCGTTTACTTACG
CAAAAGGGTATCCAGCTGTTGTGAATAACAGTAAAATGACGGAACTTTTAATGGAAACAGCGGCATCGTTTCACCCAGCA
GAAAAGTTGCATGAAATCGAGCCTGTTATGGGTGGAGAAGACTTTTCTTATTATTTACAACGTGTTCCAGGCGCGTTCTT
TTTCACTGGTGCTGGAAATGAGGAGAAGGGGATCGTTTATCCTCACCACCACCCTAAGTTTGATATTGACGAGCGGGCTA
TGCTTGTGGCCGCCAAACACCTAGGCGCAGCTGCTTTATCCTTCTTAGGCACTGGAGATAAAAAGTAA

Upstream 100 bases:

>100_bases
GCTTTTGAAAATGTCCCAGAACTCTGATTAAGGCAGTATGTTTTATTTGATGGTATCCTTTTAGGGTACCTTTTTTGTAC
ATAAATGAGGAGGGGTGTCG

Downstream 100 bases:

>100_bases
CACGGAGGCGAATCATAAGCCTCCGTTTTTTTGTTCGTTTTGTTCAAGCGAACAATTGGCCGAGAAAAGTTGCCAAATAA
GGCAATTATGGCAGGAATGT

Product: N-acyl-L-amino acid amidohydrolase

Products: carboxylate; L-amino acid

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MQESLFKKLESLYPEMVELRRDFHAEPELAFEEEVTPRKIASYLQNLGIDVRTQVGGRGVVGTIKGKKPGKTVALRADFD
ALPIQEETGLPFASKIPGKMHACGHDGHTATLLVLAKALVAMRDELEGTVVLIHQFAEEFAPGGAIAMIEDGCLDGVDAI
FGTHLWSPLPYGEVGYSYDRLMAASDRFEVNIQGKGGHGALPHETVDAVMVGSSIALMLQQLVSRNVNPLEPAVVTIASF
HAGGAFNVISDTAKLEGTVRTFSESVQDQLIARMEETIKGVCEASGATYSFTYAKGYPAVVNNSKMTELLMETAASFHPA
EKLHEIEPVMGGEDFSYYLQRVPGAFFFTGAGNEEKGIVYPHHHPKFDIDERAMLVAAKHLGAAALSFLGTGDKK

Sequences:

>Translated_395_residues
MQESLFKKLESLYPEMVELRRDFHAEPELAFEEEVTPRKIASYLQNLGIDVRTQVGGRGVVGTIKGKKPGKTVALRADFD
ALPIQEETGLPFASKIPGKMHACGHDGHTATLLVLAKALVAMRDELEGTVVLIHQFAEEFAPGGAIAMIEDGCLDGVDAI
FGTHLWSPLPYGEVGYSYDRLMAASDRFEVNIQGKGGHGALPHETVDAVMVGSSIALMLQQLVSRNVNPLEPAVVTIASF
HAGGAFNVISDTAKLEGTVRTFSESVQDQLIARMEETIKGVCEASGATYSFTYAKGYPAVVNNSKMTELLMETAASFHPA
EKLHEIEPVMGGEDFSYYLQRVPGAFFFTGAGNEEKGIVYPHHHPKFDIDERAMLVAAKHLGAAALSFLGTGDKK
>Mature_395_residues
MQESLFKKLESLYPEMVELRRDFHAEPELAFEEEVTPRKIASYLQNLGIDVRTQVGGRGVVGTIKGKKPGKTVALRADFD
ALPIQEETGLPFASKIPGKMHACGHDGHTATLLVLAKALVAMRDELEGTVVLIHQFAEEFAPGGAIAMIEDGCLDGVDAI
FGTHLWSPLPYGEVGYSYDRLMAASDRFEVNIQGKGGHGALPHETVDAVMVGSSIALMLQQLVSRNVNPLEPAVVTIASF
HAGGAFNVISDTAKLEGTVRTFSESVQDQLIARMEETIKGVCEASGATYSFTYAKGYPAVVNNSKMTELLMETAASFHPA
EKLHEIEPVMGGEDFSYYLQRVPGAFFFTGAGNEEKGIVYPHHHPKFDIDERAMLVAAKHLGAAALSFLGTGDKK

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=440, Percent_Identity=27.9545454545455, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.14

Molecular weight: Translated: 42739; Mature: 42739

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESLFKKLESLYPEMVELRRDFHAEPELAFEEEVTPRKIASYLQNLGIDVRTQVGGRGV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCE
VGTIKGKKPGKTVALRADFDALPIQEETGLPFASKIPGKMHACGHDGHTATLLVLAKALV
EEEECCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
AMRDELEGTVVLIHQFAEEFAPGGAIAMIEDGCLDGVDAIFGTHLWSPLPYGEVGYSYDR
HHHHHCCCCEEHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
LMAASDRFEVNIQGKGGHGALPHETVDAVMVGSSIALMLQQLVSRNVNPLEPAVVTIASF
HHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHH
HAGGAFNVISDTAKLEGTVRTFSESVQDQLIARMEETIKGVCEASGATYSFTYAKGYPAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCE
VNNSKMTELLMETAASFHPAEKLHEIEPVMGGEDFSYYLQRVPGAFFFTGAGNEEKGIVY
ECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEC
PHHHPKFDIDERAMLVAAKHLGAAALSFLGTGDKK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQESLFKKLESLYPEMVELRRDFHAEPELAFEEEVTPRKIASYLQNLGIDVRTQVGGRGV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCE
VGTIKGKKPGKTVALRADFDALPIQEETGLPFASKIPGKMHACGHDGHTATLLVLAKALV
EEEECCCCCCCEEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
AMRDELEGTVVLIHQFAEEFAPGGAIAMIEDGCLDGVDAIFGTHLWSPLPYGEVGYSYDR
HHHHHCCCCEEHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHH
LMAASDRFEVNIQGKGGHGALPHETVDAVMVGSSIALMLQQLVSRNVNPLEPAVVTIASF
HHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHH
HAGGAFNVISDTAKLEGTVRTFSESVQDQLIARMEETIKGVCEASGATYSFTYAKGYPAV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCE
VNNSKMTELLMETAASFHPAEKLHEIEPVMGGEDFSYYLQRVPGAFFFTGAGNEEKGIVY
ECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEC
PHHHPKFDIDERAMLVAAKHLGAAALSFLGTGDKK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-acyl-L-amino acid; H2O

Specific reaction: An N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]