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The map label for this gene is ribB [H]

Identifier: 56963576

GI number: 56963576

Start: 1930644

End: 1931288

Strand: Direct

Name: ribB [H]

Synonym: ABC1811

Alternate gene names: 56963576

Gene position: 1930644-1931288 (Clockwise)

Preceding gene: 56963574

Following gene: 56963577

Centisome position: 44.86

GC content: 44.5

Gene sequence:

>645_bases
ATGTTTACAGGTATCATCGAAGAAATGGGCAAAGTTGCTTCTGTGTCAAAAAAAGGCAAAGCGATGACATTGGCTGTTAA
TTGCAAAACCGTTTTGGCGGACGCCGCAATTGGCGACAGCATCGCTGTGAATGGAGTTTGTTTAACGGTTACGGCAATAT
CTGAAAGCCAATTTCAAGCGGACGTGATGCCAGAGACATACGAAGCGACAACGATTAAACAGCTTGTTCCAGGGCAATTT
GTTAATTTGGAACGGGCGATGGCTGTCGGCAGCCGCTTTGGTGGGCATATCATTTCTGGCCATGTCGATGGAGTTGGCAC
GATTCAAAAAAGACAACCAGTTGAGAATGCTGTGCTATTCGAAGTGGAAGCAGACCGAGAACTTGTTCGCTATATCGTTC
AAAAAGGGTCGATTGCTGTTGATGGAACAAGTTTGACGGTGTTTGCCGTTACTGATACAAGCTTTACGATTTCAATTATT
CCGCACACGCTTGAGATGACGATTATGGGCACAAAGAAACCTGGTGACCATGTTAATTTGGAATGCGACATTATCGGCAA
ATACGTTGAGAAACTTCTTGCCCCGAAAGAAAGTGCCGTTCGTACGCCTTTGTCGCAGCTTCTTAAAGAAAATAGCTATA
TGTAA

Upstream 100 bases:

>100_bases
TTATTTGTTGTGCGCAAAAACGTATGAAACCATACGTTTCTTTCCTGTACCCTGAAGGCGTGTTCTTCAGGGTTTTTTCT
ATTTAAAAGGGGGCATGACT

Downstream 100 bases:

>100_bases
AGGGGAGAACAACGTGTTTGAATCGATTGATGAAGCGATCACACAATTAAAAGCGGGGGGAATGATCCTCGTTGTAGATG
ATGAAGACCGGGAGAATGAA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MFTGIIEEMGKVASVSKKGKAMTLAVNCKTVLADAAIGDSIAVNGVCLTVTAISESQFQADVMPETYEATTIKQLVPGQF
VNLERAMAVGSRFGGHIISGHVDGVGTIQKRQPVENAVLFEVEADRELVRYIVQKGSIAVDGTSLTVFAVTDTSFTISII
PHTLEMTIMGTKKPGDHVNLECDIIGKYVEKLLAPKESAVRTPLSQLLKENSYM

Sequences:

>Translated_214_residues
MFTGIIEEMGKVASVSKKGKAMTLAVNCKTVLADAAIGDSIAVNGVCLTVTAISESQFQADVMPETYEATTIKQLVPGQF
VNLERAMAVGSRFGGHIISGHVDGVGTIQKRQPVENAVLFEVEADRELVRYIVQKGSIAVDGTSLTVFAVTDTSFTISII
PHTLEMTIMGTKKPGDHVNLECDIIGKYVEKLLAPKESAVRTPLSQLLKENSYM
>Mature_214_residues
MFTGIIEEMGKVASVSKKGKAMTLAVNCKTVLADAAIGDSIAVNGVCLTVTAISESQFQADVMPETYEATTIKQLVPGQF
VNLERAMAVGSRFGGHIISGHVDGVGTIQKRQPVENAVLFEVEADRELVRYIVQKGSIAVDGTSLTVFAVTDTSFTISII
PHTLEMTIMGTKKPGDHVNLECDIIGKYVEKLLAPKESAVRTPLSQLLKENSYM

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=210, Percent_Identity=39.5238095238095, Blast_Score=137, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6319733, Length=231, Percent_Identity=41.1255411255411, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22991; Mature: 22991

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIEEMGKVASVSKKGKAMTLAVNCKTVLADAAIGDSIAVNGVCLTVTAISESQFQA
CCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCEEECCEEEEEEEECCCCCEE
DVMPETYEATTIKQLVPGQFVNLERAMAVGSRFGGHIISGHVDGVGTIQKRQPVENAVLF
CCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHCCCCCCEEEE
EVEADRELVRYIVQKGSIAVDGTSLTVFAVTDTSFTISIIPHTLEMTIMGTKKPGDHVNL
EEECCHHHHHHHHHCCCEEECCCEEEEEEEECCCEEEEEECCEEEEEEEECCCCCCCEEE
ECDIIGKYVEKLLAPKESAVRTPLSQLLKENSYM
EHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFTGIIEEMGKVASVSKKGKAMTLAVNCKTVLADAAIGDSIAVNGVCLTVTAISESQFQA
CCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHCCCCEEECCEEEEEEEECCCCCEE
DVMPETYEATTIKQLVPGQFVNLERAMAVGSRFGGHIISGHVDGVGTIQKRQPVENAVLF
CCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHCCCCCCEEEE
EVEADRELVRYIVQKGSIAVDGTSLTVFAVTDTSFTISIIPHTLEMTIMGTKKPGDHVNL
EEECCHHHHHHHHHCCCEEECCCEEEEEEEECCCEEEEEECCEEEEEEEECCCCCCCEEE
ECDIIGKYVEKLLAPKESAVRTPLSQLLKENSYM
EHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2106516; 7934829; 9384377; 7473709 [H]