BacMap

Definition	Bacillus clausii KSM-K16, complete genome.
Accession	NC_006582
Length	4,303,871

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The map label for this gene is iolA2

Identifier: 56963574

GI number: 56963574

Start: 1927071

End: 1928531

Strand: Direct

Name: iolA2

Synonym: ABC1809

Alternate gene names: 56963574

Gene position: 1927071-1928531 (Clockwise)

Preceding gene: 56963573

Following gene: 56963576

Centisome position: 44.78

GC content: 49.01

Gene sequence:

>1461_bases
ATGACAACTACGAAAGTGAAAACGGTGAAAAACTGGATTGACGGCGCTTGGGTCGAAGCATCTACGGCTGATACGGAAGT
CGTACCAAACCCGGCGACGGGAGAAGCTATTGCTTACGTGCCGCTTTCAGGCGAACGTGATGTGGAGCAGGCGGTGGCGA
GCGCAAAGCGTGCCTATGAAACATGGAAAACAGTTCCTGTTCCCGAGCGTACTCGGTACATGTTTGCGTATTTGGAGCAA
CTAAAGAAAAATAGGGAGCAATTGGCGCAGCTGATTACGCTAGAAAACGGCAAGACGATCAAAGATGCTAGAGGGGAAGT
CCAACGTGGCATTGAGTGTGTGGAGCTAGCTACGTCGACACCGACAATGATGATGGGCGACGCTCTTCCCGATATTGCCA
GCGGGATTGACGGTTCGATTTGGCGCTATCCTTTAGGGGTTGTTGCTGGCATTACGCCGTTTAATTTTCCAATGATGGTC
CCGTTATGGATGTTTCCACTTGCGATTGCAGCAGGGAATACATTTGTTCTTAAAACCTCTGAACGGACACCGCTTTTAGC
TGAACAACTTGTCTCGCTTATGCATGAAGTCGGTTTGCCTAGAGGTGTGTTGAATTTAGTGAATGGCGGCAAAGCAGTGG
TTAATGGCTTGTTAAACCACCCTGACGTTGAAGCGATTTCGTTTGTCGGCTCTGAGCCAGTGGCTCGCTATGTATATGAA
ACAGGTACAGCAAATGGCAAACGAGTTCAGGCCCTTGCAGGCGCAAAAAACCACGCTGTCGTTTTAGCTGATTGTGAACT
AGATAAGACGGTCCAAGGGGTCATCGGCGCCGCCTTTGCATCGAGTGGCGAACGGTGTATGGCTTGTTCCGTGGTCGCCG
TCGTTGAAGAAGTAGCGGATGCCTTTATTGAAAAACTAACGGCAGAGACGAAGAAATTGACAGTCGGCAACGGCAAAAAC
GATGAACATTTTGTCGGCCCGCTCATTCGCCAAAGCCATAAAGACAAAGTTGTTAAATACATTGAACAAGGAGTAGAGCA
AGGGGCAGAACTGTTGGTTGACGGACGCAACGCAACGAGTGAGGAAGCGGGCTATTACCTTGGCGCAACTTTGTTCGACC
ACGTGACACCAGAGATGACGATCTGGCAAGAAGAATTGTTTGCCCCAGTGCTCAGCATTGTCCGTGTGCGAGATTTAGAA
GAGGCAATTGCTTTAACGAACCGATCTCGCTTTGCGAACGGGGCCGTTATTTACACATCAAGCGGCAAGGCGGCACAACA
CTTTCGAAATGCAATCGATGCCGGGATGGTTGGCATCAATGTGAATGTGCCTGCTCCAATGGCATTCTTTTCATTTGCCG
GTAATAAAGCATCGTTTTTTGGCGATCTTGGCACGAATGGACGTGACGGCATCCAATTTTATACAAGGAAAAAAGTCGTT
ACCGAACGCTGGTTCAATTAA

Upstream 100 bases:

>100_bases
ACGCTGAGCGAGCAGGACTTGGAGAAAAGGACATGGCCGTGCTGTTTGAACGGATTGGGGAACAGACAATTTCCTTTAAA
GCGGAAGGAGTGGCTAAACG

Downstream 100 bases:

>100_bases
TAAAGGGAACGTTGTTATCGCTTAAAAACCAGTGTCTACTTTTAGAGCCACCCGCAAAAGGCAGGTGGCTCAGACTGTAG
GCAAATCGTTCGTTGCTTCT

Product: methylmalonate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: MMSA dehydrogenase 2; MMSDH 2; MSDH 2; Malonate semialdehyde dehydrogenase [acetylating] 2; MSA dehydrogenase 2

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MTTTKVKTVKNWIDGAWVEASTADTEVVPNPATGEAIAYVPLSGERDVEQAVASAKRAYETWKTVPVPERTRYMFAYLEQ
LKKNREQLAQLITLENGKTIKDARGEVQRGIECVELATSTPTMMMGDALPDIASGIDGSIWRYPLGVVAGITPFNFPMMV
PLWMFPLAIAAGNTFVLKTSERTPLLAEQLVSLMHEVGLPRGVLNLVNGGKAVVNGLLNHPDVEAISFVGSEPVARYVYE
TGTANGKRVQALAGAKNHAVVLADCELDKTVQGVIGAAFASSGERCMACSVVAVVEEVADAFIEKLTAETKKLTVGNGKN
DEHFVGPLIRQSHKDKVVKYIEQGVEQGAELLVDGRNATSEEAGYYLGATLFDHVTPEMTIWQEELFAPVLSIVRVRDLE
EAIALTNRSRFANGAVIYTSSGKAAQHFRNAIDAGMVGINVNVPAPMAFFSFAGNKASFFGDLGTNGRDGIQFYTRKKVV
TERWFN

Sequences:

>Translated_486_residues
MTTTKVKTVKNWIDGAWVEASTADTEVVPNPATGEAIAYVPLSGERDVEQAVASAKRAYETWKTVPVPERTRYMFAYLEQ
LKKNREQLAQLITLENGKTIKDARGEVQRGIECVELATSTPTMMMGDALPDIASGIDGSIWRYPLGVVAGITPFNFPMMV
PLWMFPLAIAAGNTFVLKTSERTPLLAEQLVSLMHEVGLPRGVLNLVNGGKAVVNGLLNHPDVEAISFVGSEPVARYVYE
TGTANGKRVQALAGAKNHAVVLADCELDKTVQGVIGAAFASSGERCMACSVVAVVEEVADAFIEKLTAETKKLTVGNGKN
DEHFVGPLIRQSHKDKVVKYIEQGVEQGAELLVDGRNATSEEAGYYLGATLFDHVTPEMTIWQEELFAPVLSIVRVRDLE
EAIALTNRSRFANGAVIYTSSGKAAQHFRNAIDAGMVGINVNVPAPMAFFSFAGNKASFFGDLGTNGRDGIQFYTRKKVV
TERWFN
>Mature_485_residues
TTTKVKTVKNWIDGAWVEASTADTEVVPNPATGEAIAYVPLSGERDVEQAVASAKRAYETWKTVPVPERTRYMFAYLEQL
KKNREQLAQLITLENGKTIKDARGEVQRGIECVELATSTPTMMMGDALPDIASGIDGSIWRYPLGVVAGITPFNFPMMVP
LWMFPLAIAAGNTFVLKTSERTPLLAEQLVSLMHEVGLPRGVLNLVNGGKAVVNGLLNHPDVEAISFVGSEPVARYVYET
GTANGKRVQALAGAKNHAVVLADCELDKTVQGVIGAAFASSGERCMACSVVAVVEEVADAFIEKLTAETKKLTVGNGKND
EHFVGPLIRQSHKDKVVKYIEQGVEQGAELLVDGRNATSEEAGYYLGATLFDHVTPEMTIWQEELFAPVLSIVRVRDLEE
AIALTNRSRFANGAVIYTSSGKAAQHFRNAIDAGMVGINVNVPAPMAFFSFAGNKASFFGDLGTNGRDGIQFYTRKKVVT
ERWFN

Specific function: Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. IolA subfamily

Homologues:

Organism=Homo sapiens, GI11095441, Length=481, Percent_Identity=42.4116424116424, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI115387104, Length=476, Percent_Identity=31.5126050420168, Blast_Score=242, Evalue=6e-64,
Organism=Homo sapiens, GI25777732, Length=485, Percent_Identity=30.5154639175258, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI21361176, Length=495, Percent_Identity=30.5050505050505, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI25777730, Length=484, Percent_Identity=30.7851239669421, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI153266822, Length=488, Percent_Identity=31.5573770491803, Blast_Score=221, Evalue=8e-58,
Organism=Homo sapiens, GI12007648, Length=492, Percent_Identity=28.6585365853659, Blast_Score=220, Evalue=3e-57,
Organism=Homo sapiens, GI25777724, Length=491, Percent_Identity=29.1242362525458, Blast_Score=211, Evalue=9e-55,
Organism=Homo sapiens, GI238814322, Length=485, Percent_Identity=30.1030927835052, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI21614513, Length=485, Percent_Identity=30.9278350515464, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI25777728, Length=424, Percent_Identity=29.4811320754717, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI25777726, Length=490, Percent_Identity=26.9387755102041, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI25952152, Length=487, Percent_Identity=26.0780287474333, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI4507229, Length=478, Percent_Identity=30.3347280334728, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI25777721, Length=491, Percent_Identity=29.3279022403259, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI188035924, Length=461, Percent_Identity=26.0303687635575, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI310128103, Length=457, Percent_Identity=26.0393873085339, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI310128093, Length=437, Percent_Identity=26.5446224256293, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI301500698, Length=289, Percent_Identity=27.681660899654, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI310128091, Length=436, Percent_Identity=25, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI206597441, Length=442, Percent_Identity=24.6606334841629, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI206597439, Length=442, Percent_Identity=24.6606334841629, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI22907049, Length=442, Percent_Identity=24.6606334841629, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI310128087, Length=260, Percent_Identity=28.4615384615385, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI4557303, Length=337, Percent_Identity=24.0356083086053, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI73466520, Length=337, Percent_Identity=24.0356083086053, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI73695881, Length=331, Percent_Identity=25.3776435045317, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI73695879, Length=331, Percent_Identity=25.3776435045317, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI25777736, Length=496, Percent_Identity=23.1854838709677, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI25777734, Length=496, Percent_Identity=23.1854838709677, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI238859541, Length=496, Percent_Identity=23.1854838709677, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI310128099, Length=212, Percent_Identity=29.7169811320755, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310128101, Length=212, Percent_Identity=29.7169811320755, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI223972651, Length=446, Percent_Identity=22.6457399103139, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI4502043, Length=340, Percent_Identity=26.1764705882353, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI238814371, Length=340, Percent_Identity=26.1764705882353, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI71773324, Length=338, Percent_Identity=26.3313609467456, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI310128089, Length=347, Percent_Identity=22.7665706051873, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI310128095, Length=297, Percent_Identity=22.8956228956229, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI310128097, Length=240, Percent_Identity=24.1666666666667, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081896, Length=483, Percent_Identity=33.1262939958592, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789015, Length=474, Percent_Identity=31.0126582278481, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1787558, Length=464, Percent_Identity=31.0344827586207, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786504, Length=474, Percent_Identity=31.0126582278481, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI87081926, Length=433, Percent_Identity=29.5612009237875, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787684, Length=471, Percent_Identity=29.723991507431, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI87082295, Length=466, Percent_Identity=30.68669527897, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1788042, Length=455, Percent_Identity=27.9120879120879, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1787715, Length=454, Percent_Identity=27.0925110132159, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI1787250, Length=451, Percent_Identity=26.8292682926829, Blast_Score=138, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71986308, Length=479, Percent_Identity=44.4676409185804, Blast_Score=439, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI133930964, Length=485, Percent_Identity=31.1340206185567, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17562198, Length=484, Percent_Identity=30.7851239669421, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI25144435, Length=484, Percent_Identity=29.7520661157025, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17534119, Length=470, Percent_Identity=29.7872340425532, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI25143876, Length=489, Percent_Identity=28.2208588957055, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI25143874, Length=489, Percent_Identity=28.2208588957055, Blast_Score=186, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI32564736, Length=412, Percent_Identity=30.5825242718447, Blast_Score=178, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17551164, Length=459, Percent_Identity=28.5403050108932, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=461, Percent_Identity=27.9826464208243, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71995606, Length=487, Percent_Identity=27.1047227926078, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71995613, Length=418, Percent_Identity=26.0765550239234, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17564084, Length=351, Percent_Identity=27.9202279202279, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17534447, Length=387, Percent_Identity=23.7726098191214, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564151, Length=387, Percent_Identity=23.7726098191214, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=450, Percent_Identity=24.4444444444444, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25146391, Length=450, Percent_Identity=24.4444444444444, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=450, Percent_Identity=24.4444444444444, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115532534, Length=271, Percent_Identity=25.0922509225092, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71990744, Length=304, Percent_Identity=24.3421052631579, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324950, Length=432, Percent_Identity=33.3333333333333, Blast_Score=246, Evalue=6e-66,
Organism=Saccharomyces cerevisiae, GI6320917, Length=441, Percent_Identity=32.8798185941043, Blast_Score=224, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6323822, Length=475, Percent_Identity=31.3684210526316, Blast_Score=213, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6325196, Length=434, Percent_Identity=29.9539170506912, Blast_Score=203, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6323821, Length=479, Percent_Identity=30.4801670146138, Blast_Score=200, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6319478, Length=474, Percent_Identity=27.4261603375527, Blast_Score=189, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6321828, Length=467, Percent_Identity=26.1241970021413, Blast_Score=151, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6321826, Length=430, Percent_Identity=26.046511627907, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24638876, Length=479, Percent_Identity=41.7536534446764, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24638878, Length=479, Percent_Identity=41.7536534446764, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI281362580, Length=479, Percent_Identity=31.9415448851775, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI62472918, Length=479, Percent_Identity=31.9415448851775, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI62472926, Length=479, Percent_Identity=31.9415448851775, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI62472936, Length=479, Percent_Identity=31.9415448851775, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI21356737, Length=479, Percent_Identity=31.9415448851775, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24650465, Length=484, Percent_Identity=32.6446280991736, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI20129399, Length=492, Percent_Identity=30.6910569105691, Blast_Score=218, Evalue=9e-57,
Organism=Drosophila melanogaster, GI24585660, Length=484, Percent_Identity=28.3057851239669, Blast_Score=212, Evalue=5e-55,
Organism=Drosophila melanogaster, GI24666674, Length=471, Percent_Identity=27.8131634819533, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24668425, Length=284, Percent_Identity=28.8732394366197, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24668417, Length=284, Percent_Identity=28.8732394366197, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24668413, Length=284, Percent_Identity=28.8732394366197, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI28571798, Length=428, Percent_Identity=24.0654205607477, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571796, Length=428, Percent_Identity=24.0654205607477, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571794, Length=428, Percent_Identity=24.0654205607477, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571802, Length=428, Percent_Identity=24.0654205607477, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571800, Length=428, Percent_Identity=24.0654205607477, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571806, Length=428, Percent_Identity=24.0654205607477, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28574525, Length=479, Percent_Identity=21.7118997912317, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45552499, Length=343, Percent_Identity=22.7405247813411, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281360303, Length=343, Percent_Identity=22.7405247813411, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281360301, Length=343, Percent_Identity=22.7405247813411, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281360299, Length=343, Percent_Identity=22.7405247813411, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281360297, Length=343, Percent_Identity=22.7405247813411, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281360295, Length=343, Percent_Identity=22.7405247813411, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24586250, Length=343, Percent_Identity=22.7405247813411, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLA2_BACSK (Q5WH11)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175305.1
- HSSP:   P42412
- ProteinModelPortal:   Q5WH11
- SMR:   Q5WH11
- STRING:   Q5WH11
- EnsemblBacteria:   EBBACT00000046639
- GeneID:   3202963
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1809
- NMPDR:   fig|66692.3.peg.1757
- eggNOG:   COG1012
- GeneTree:   EBGT00070000031871
- HOGENOM:   HBG752218
- OMA:   NGAGVDM
- ProtClustDB:   CLSK873284
- BioCyc:   BCLA66692:ABC1809-MONOMER
- HAMAP:   MF_01670
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR010061
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699
- PANTHER:   PTHR11699:SF27
- TIGRFAMs:   TIGR01722

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.27; =1.2.1.18

Molecular weight: Translated: 52753; Mature: 52622

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 286-286 BINDING 385-385

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTKVKTVKNWIDGAWVEASTADTEVVPNPATGEAIAYVPLSGERDVEQAVASAKRAYE
CCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
TWKTVPVPERTRYMFAYLEQLKKNREQLAQLITLENGKTIKDARGEVQRGIECVELATST
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCC
PTMMMGDALPDIASGIDGSIWRYPLGVVAGITPFNFPMMVPLWMFPLAIAAGNTFVLKTS
CCHHCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEC
ERTPLLAEQLVSLMHEVGLPRGVLNLVNGGKAVVNGLLNHPDVEAISFVGSEPVARYVYE
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHCCCCCHHHHHHCCCCHHHHHHHH
TGTANGKRVQALAGAKNHAVVLADCELDKTVQGVIGAAFASSGERCMACSVVAVVEEVAD
CCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AFIEKLTAETKKLTVGNGKNDEHFVGPLIRQSHKDKVVKYIEQGVEQGAELLVDGRNATS
HHHHHHHHHHHEEEECCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
EEAGYYLGATLFDHVTPEMTIWQEELFAPVLSIVRVRDLEEAIALTNRSRFANGAVIYTS
HHCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
SGKAAQHFRNAIDAGMVGINVNVPAPMAFFSFAGNKASFFGDLGTNGRDGIQFYTRKKVV
CCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHH
TERWFN
HHHCCC
>Mature Secondary Structure 
TTTKVKTVKNWIDGAWVEASTADTEVVPNPATGEAIAYVPLSGERDVEQAVASAKRAYE
CCCHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
TWKTVPVPERTRYMFAYLEQLKKNREQLAQLITLENGKTIKDARGEVQRGIECVELATST
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHCCC
PTMMMGDALPDIASGIDGSIWRYPLGVVAGITPFNFPMMVPLWMFPLAIAAGNTFVLKTS
CCHHCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEC
ERTPLLAEQLVSLMHEVGLPRGVLNLVNGGKAVVNGLLNHPDVEAISFVGSEPVARYVYE
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHCCCCCHHHHHHCCCCHHHHHHHH
TGTANGKRVQALAGAKNHAVVLADCELDKTVQGVIGAAFASSGERCMACSVVAVVEEVAD
CCCCCCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
AFIEKLTAETKKLTVGNGKNDEHFVGPLIRQSHKDKVVKYIEQGVEQGAELLVDGRNATS
HHHHHHHHHHHEEEECCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
EEAGYYLGATLFDHVTPEMTIWQEELFAPVLSIVRVRDLEEAIALTNRSRFANGAVIYTS
HHCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
SGKAAQHFRNAIDAGMVGINVNVPAPMAFFSFAGNKASFFGDLGTNGRDGIQFYTRKKVV
CCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHH
TERWFN
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA