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The map label for this gene is spoIIAB

Identifier: 56963559

GI number: 56963559

Start: 1911696

End: 1912136

Strand: Direct

Name: spoIIAB

Synonym: ABC1794

Alternate gene names: 56963559

Gene position: 1911696-1912136 (Clockwise)

Preceding gene: 56963558

Following gene: 56963560

Centisome position: 44.42

GC content: 44.44

Gene sequence:

>441_bases
GTGGCCAATAAAATGAATTTAGCGTTTTCGGCTTTAAGTGAAAATGAATCTTTTGCCCGAGTGACAGTCAGTGCCTTTAT
TGCCCAACTCGATCCGACGATGGAGGAATTGACGGAAATCAAGACGATTGTCTCAGAGGCGGTCACCAATGCGATTATCC
ATGGCTACGAAAATGATCCAAATGGGCAAGTTTATATTACAGCTGAACTGAAGGATCGTGAACTCGAACTCATTATCCGC
GACGAAGGGGTAGGCATATCAGACTTGGATGAAGCAAGACAGCCGCTTTATACCTCGAAACCGGAACTAGAGCGCTCTGG
AATGGGCTTCACGATTATGGAAAATTTTTGCCAAGAGTTGAAAGTAATCTCCGAACCAATGATTGGGACAACCGTTTACG
TGAAAAAACAGCTGACCACGACGAAAGCAATGTGCAGATAA

Upstream 100 bases:

>100_bases
CCAACGATTGAGCGGTTGTTTGAGATGTCGGGCCTTTTTAAAATTATCCGGTTGGAAGAAAGCGAACGATTCGCATTGCA
AAAATTGGGGGTGGCATAAA

Downstream 100 bases:

>100_bases
GGGGTCTTGCTTATGAGTGCAGAGGTGAAAAACGGCGGCAAAAAAAAGCCACTATCCGATAAACAAGTGAAAGAGCTGAT
TGCAAAAAGCCAGGAAGGCG

Product: anti-sigma F factor

Products: NA

Alternate protein names: Stage II sporulation protein AB

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MANKMNLAFSALSENESFARVTVSAFIAQLDPTMEELTEIKTIVSEAVTNAIIHGYENDPNGQVYITAELKDRELELIIR
DEGVGISDLDEARQPLYTSKPELERSGMGFTIMENFCQELKVISEPMIGTTVYVKKQLTTTKAMCR

Sequences:

>Translated_146_residues
MANKMNLAFSALSENESFARVTVSAFIAQLDPTMEELTEIKTIVSEAVTNAIIHGYENDPNGQVYITAELKDRELELIIR
DEGVGISDLDEARQPLYTSKPELERSGMGFTIMENFCQELKVISEPMIGTTVYVKKQLTTTKAMCR
>Mature_145_residues
ANKMNLAFSALSENESFARVTVSAFIAQLDPTMEELTEIKTIVSEAVTNAIIHGYENDPNGQVYITAELKDRELELIIRD
EGVGISDLDEARQPLYTSKPELERSGMGFTIMENFCQELKVISEPMIGTTVYVKKQLTTTKAMCR

Specific function: Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases si

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SP2AB_BACSK (Q5WH26)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175290.1
- ProteinModelPortal:   Q5WH26
- SMR:   Q5WH26
- STRING:   Q5WH26
- EnsemblBacteria:   EBBACT00000048832
- GeneID:   3200721
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1794
- NMPDR:   fig|66692.3.peg.1742
- eggNOG:   COG2172
- GeneTree:   EBGT00050000001549
- HOGENOM:   HBG425195
- OMA:   KSKALCN
- ProtClustDB:   PRK03660
- BioCyc:   BCLA66692:ABC1794-MONOMER
- HAMAP:   MF_00637
- InterPro:   IPR010194
- InterPro:   IPR003594
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00387
- TIGRFAMs:   TIGR01925

Pfam domain/function: PF02518 HATPase_c; SSF55874 ATP_bd_ATPase

EC number: =2.7.11.1

Molecular weight: Translated: 16329; Mature: 16198

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKMNLAFSALSENESFARVTVSAFIAQLDPTMEELTEIKTIVSEAVTNAIIHGYENDP
CCCCHHHHHEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NGQVYITAELKDRELELIIRDEGVGISDLDEARQPLYTSKPELERSGMGFTIMENFCQEL
CCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
KVISEPMIGTTVYVKKQLTTTKAMCR
HHHCCCCCCEEEEEEHHHHHHHHHCC
>Mature Secondary Structure 
ANKMNLAFSALSENESFARVTVSAFIAQLDPTMEELTEIKTIVSEAVTNAIIHGYENDP
CCCHHHHHEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NGQVYITAELKDRELELIIRDEGVGISDLDEARQPLYTSKPELERSGMGFTIMENFCQEL
CCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHH
KVISEPMIGTTVYVKKQLTTTKAMCR
HHHCCCCCCEEEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA