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The map label for this gene is glcK [H]

Identifier: 56963496

GI number: 56963496

Start: 1858467

End: 1859447

Strand: Direct

Name: glcK [H]

Synonym: ABC1731

Alternate gene names: 56963496

Gene position: 1858467-1859447 (Clockwise)

Preceding gene: 56963495

Following gene: 56963497

Centisome position: 43.18

GC content: 47.81

Gene sequence:

>981_bases
ATGACTGAGGACTACTATGCAGGAATTGACATTGGCGGTACGACCGTAAAGTTGGCGTTTCTTACGGAAACAGGCGAGTT
AAAAGATAAATGGGAGATTCCCACAGACGTGAGCGAAAACGGCAAACATATTGTCGATCAAATCGCCGCAAGCATTCAAA
GCCGGCTGCCGCAACATGCAACCTTGTTAGGGGCTGGAGTAGGTGCACCAGGATTCATTGAAATGAAAACTGGTTTTATT
CACCATGCCGTCAATATCGGCTGGCGAAACTATCCACTAAGGGAAGAGCTTGAACGCGTCCTTGGAGTGGTTGTCCGCGT
CGACAATGACGCTAATTTGGCAGCACTTGGAGAGAAATGGCGCGGCGCAGGAGATGGCGCTGAAGAAGAGTTGTTTATCA
CACTTGGTACAGGTGTCGGCGGTGGCATTATTACAAGAGGGCAAATTCTCCACGGGTCAAGTGGAATGGGCGGCGAAATT
GGCCACATAACAGTTATCCCTGAAGGTGGGGCACCGTGCAATTGCGGCAAAACAGGCTGCCTGGAAACGGTATCTTCGGC
AACGGGCATTTTACGGATGGCCAAGGAAAAGTTAACAACAAATAAGGACAGCGCTTTGCATCGCTTTGAAGAAGGGGCGT
TAACGACAAAAGATATTTTCGATGCTGCTAAAGCTGGCGATGCACTTGCTAAAGATGTGGTAAGTGAAGCAACCTTTCAC
CTTGGTTTTGCAATAGCGAACCTGGCTAATGCGCTCAATCCAAGCAAAATCATTATTGGCGGTGGTGTTTCTAAAGCGAA
AGAAAGCTTGCTTGCTCCGCTTCGCCTCGTATTTAAGCAATTTGCGTTGCCCCGTGTTTCTGAGAGTGCTGAGATTAAAT
TGGCTCATTTAGGCAATGACGCTGGGATTTACGGTGCTGTTTGGCTTGCTATTCAGGCAAAAGCAACACAGGAAGAAGAG
ATGTTAGGAAAAAGTGAATGA

Upstream 100 bases:

>100_bases
GAACTTCATCGACTTGGCCTAATCGAACGTGGCGAATTCCAACAAGCAATGCTTGTATTAAAACGTGAACAGCGGGCTGC
AAAAATGGGGGAGAGAGCGA

Downstream 100 bases:

>100_bases
GTAAAAGGAGTCGCATGAAATGGAGTACCGGGTTGAACGAGACTTACTAGGAGAAAAACAAGTACCGAAACATGCTTATT
ATGGCATCCAATCGCTGCGG

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTEDYYAGIDIGGTTVKLAFLTETGELKDKWEIPTDVSENGKHIVDQIAASIQSRLPQHATLLGAGVGAPGFIEMKTGFI
HHAVNIGWRNYPLREELERVLGVVVRVDNDANLAALGEKWRGAGDGAEEELFITLGTGVGGGIITRGQILHGSSGMGGEI
GHITVIPEGGAPCNCGKTGCLETVSSATGILRMAKEKLTTNKDSALHRFEEGALTTKDIFDAAKAGDALAKDVVSEATFH
LGFAIANLANALNPSKIIIGGGVSKAKESLLAPLRLVFKQFALPRVSESAEIKLAHLGNDAGIYGAVWLAIQAKATQEEE
MLGKSE

Sequences:

>Translated_326_residues
MTEDYYAGIDIGGTTVKLAFLTETGELKDKWEIPTDVSENGKHIVDQIAASIQSRLPQHATLLGAGVGAPGFIEMKTGFI
HHAVNIGWRNYPLREELERVLGVVVRVDNDANLAALGEKWRGAGDGAEEELFITLGTGVGGGIITRGQILHGSSGMGGEI
GHITVIPEGGAPCNCGKTGCLETVSSATGILRMAKEKLTTNKDSALHRFEEGALTTKDIFDAAKAGDALAKDVVSEATFH
LGFAIANLANALNPSKIIIGGGVSKAKESLLAPLRLVFKQFALPRVSESAEIKLAHLGNDAGIYGAVWLAIQAKATQEEE
MLGKSE
>Mature_325_residues
TEDYYAGIDIGGTTVKLAFLTETGELKDKWEIPTDVSENGKHIVDQIAASIQSRLPQHATLLGAGVGAPGFIEMKTGFIH
HAVNIGWRNYPLREELERVLGVVVRVDNDANLAALGEKWRGAGDGAEEELFITLGTGVGGGIITRGQILHGSSGMGGEIG
HITVIPEGGAPCNCGKTGCLETVSSATGILRMAKEKLTTNKDSALHRFEEGALTTKDIFDAAKAGDALAKDVVSEATFHL
GFAIANLANALNPSKIIIGGGVSKAKESLLAPLRLVFKQFALPRVSESAEIKLAHLGNDAGIYGAVWLAIQAKATQEEEM
LGKSE

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI190014632, Length=270, Percent_Identity=31.4814814814815, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI298566325, Length=270, Percent_Identity=31.4814814814815, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI4885285, Length=270, Percent_Identity=31.4814814814815, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI298566315, Length=270, Percent_Identity=31.4814814814815, Blast_Score=109, Evalue=3e-24,
Organism=Escherichia coli, GI1787878, Length=289, Percent_Identity=32.1799307958478, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1786891, Length=316, Percent_Identity=31.0126582278481, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87081733, Length=315, Percent_Identity=30.1587301587302, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787363, Length=317, Percent_Identity=28.0757097791798, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082127, Length=167, Percent_Identity=33.5329341317365, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082230, Length=263, Percent_Identity=31.1787072243346, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790522, Length=277, Percent_Identity=25.9927797833935, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34353; Mature: 34221

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDYYAGIDIGGTTVKLAFLTETGELKDKWEIPTDVSENGKHIVDQIAASIQSRLPQHA
CCCCEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
TLLGAGVGAPGFIEMKTGFIHHAVNIGWRNYPLREELERVLGVVVRVDNDANLAALGEKW
HEEECCCCCCCEEEEECCCEEHHEECCCCCCCHHHHHHHHHEEEEEECCCCCEEHHHHHH
RGAGDGAEEELFITLGTGVGGGIITRGQILHGSSGMGGEIGHITVIPEGGAPCNCGKTGC
CCCCCCCCCEEEEEEECCCCCCEEECCEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHH
LETVSSATGILRMAKEKLTTNKDSALHRFEEGALTTKDIFDAAKAGDALAKDVVSEATFH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGFAIANLANALNPSKIIIGGGVSKAKESLLAPLRLVFKQFALPRVSESAEIKLAHLGND
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
AGIYGAVWLAIQAKATQEEEMLGKSE
CCCCEEEEEEEECCCCCHHHHCCCCC
>Mature Secondary Structure 
TEDYYAGIDIGGTTVKLAFLTETGELKDKWEIPTDVSENGKHIVDQIAASIQSRLPQHA
CCCEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHH
TLLGAGVGAPGFIEMKTGFIHHAVNIGWRNYPLREELERVLGVVVRVDNDANLAALGEKW
HEEECCCCCCCEEEEECCCEEHHEECCCCCCCHHHHHHHHHEEEEEECCCCCEEHHHHHH
RGAGDGAEEELFITLGTGVGGGIITRGQILHGSSGMGGEIGHITVIPEGGAPCNCGKTGC
CCCCCCCCCEEEEEEECCCCCCEEECCEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHH
LETVSSATGILRMAKEKLTTNKDSALHRFEEGALTTKDIFDAAKAGDALAKDVVSEATFH
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LGFAIANLANALNPSKIIIGGGVSKAKESLLAPLRLVFKQFALPRVSESAEIKLAHLGND
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
AGIYGAVWLAIQAKATQEEEMLGKSE
CCCCEEEEEEEECCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]