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The map label for this gene is prmA

Identifier: 56963426

GI number: 56963426

Start: 1791518

End: 1792465

Strand: Direct

Name: prmA

Synonym: ABC1661

Alternate gene names: 56963426

Gene position: 1791518-1792465 (Clockwise)

Preceding gene: 56963425

Following gene: 56963427

Centisome position: 41.63

GC content: 49.37

Gene sequence:

>948_bases
ATGAAATGGGCTGAATTTCGCGTCCATACGACGCAGGAAGCGGTGGAGCCTGTATCAAATATTCTCCATGAATTAGGTGC
CGCAGGCGTAGCGATTGAGGATCCCCAGGACCTTGTGACAGAGTGGAGTGTAAAGTATGGGGAAGTGTATGAGCTCTCCC
CGGAGGATTACCCCGATGAAGGTGTGATGGTTAAAGCCTATTTTCCAATGGGCGCCACTTTTAAGGAAACGATTGCTGAA
GTAAGAAGGCGCGTCCATAATCTCGTTTCCTTTCAAATTGACATTGGCCACGGGACAATGGATTATACAGAAGTAAAAGA
AGAGGACTGGGCAACGGCATGGAAAAGCTTTTACCACCCTGTTCAAGTAACGGAGCAAGTCACCATTGTGCCGACATGGG
AAGAGTATAGCGCCCGTCCAGGGGAAATCGTCATCGAATTAGATCCAGGGATGGCGTTTGGCACTGGGACACATCCAACA
ACGATTCTGTCGCTTCAAGCACTTGAGCAAGCGGTCAAGCAAGGGGATGCAGTCATCGATGTTGGCACCGGTTCAGGTAT
ACTTGCAATTGCTGCATGGAAATTCGGCGCCGAGTCTATTACAGCGTTGGACTTGGATGAGGTTGCTGTGAATAGCGCGA
AGGCGAATGTCGCCCTAAACAGCGCTAGTGACTTCGTGCATGTGCAGCAAGGCAACCTCCTAGACGATGTTGCTAGCGAA
AGCGCTGATGTGCTTGTTAGCAACATTCTAGCAGAAGTCATTTTGCAGTTTACGGCCGATGCTTACCGTGTTGTCAAACG
AGGCGGGCTCTTTTTAACTTCTGGAATCATCTCTAGCAAAAGAGAAGCTGTCGAAGGGGCATTAAAGGCAGTAGGTTTTC
TGATTCAGGAAGTGAACGAATTGGACGACTGGGTAGCGATTGTTGCGCAAAAACCCAGCCAAGCGTAG

Upstream 100 bases:

>100_bases
GTATGAGCGGCGGAAGGCCAGAGGAGCAAAATGACGGATTTTTTGACAAACTGCGCCGTGCTTTCAAAGGCGATTGAAAT
CAAGCGAGGTGGCCGAACAA

Downstream 100 bases:

>100_bases
GTAGGTGCAAAGGCATGCAGCGTTACTTTATTAAAAATGAACAGTTGACAAATGAAGTTGTCGAAATAACTGGCGACGAC
GCCGCGCACATTACAAAAGT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKWAEFRVHTTQEAVEPVSNILHELGAAGVAIEDPQDLVTEWSVKYGEVYELSPEDYPDEGVMVKAYFPMGATFKETIAE
VRRRVHNLVSFQIDIGHGTMDYTEVKEEDWATAWKSFYHPVQVTEQVTIVPTWEEYSARPGEIVIELDPGMAFGTGTHPT
TILSLQALEQAVKQGDAVIDVGTGSGILAIAAWKFGAESITALDLDEVAVNSAKANVALNSASDFVHVQQGNLLDDVASE
SADVLVSNILAEVILQFTADAYRVVKRGGLFLTSGIISSKREAVEGALKAVGFLIQEVNELDDWVAIVAQKPSQA

Sequences:

>Translated_315_residues
MKWAEFRVHTTQEAVEPVSNILHELGAAGVAIEDPQDLVTEWSVKYGEVYELSPEDYPDEGVMVKAYFPMGATFKETIAE
VRRRVHNLVSFQIDIGHGTMDYTEVKEEDWATAWKSFYHPVQVTEQVTIVPTWEEYSARPGEIVIELDPGMAFGTGTHPT
TILSLQALEQAVKQGDAVIDVGTGSGILAIAAWKFGAESITALDLDEVAVNSAKANVALNSASDFVHVQQGNLLDDVASE
SADVLVSNILAEVILQFTADAYRVVKRGGLFLTSGIISSKREAVEGALKAVGFLIQEVNELDDWVAIVAQKPSQA
>Mature_315_residues
MKWAEFRVHTTQEAVEPVSNILHELGAAGVAIEDPQDLVTEWSVKYGEVYELSPEDYPDEGVMVKAYFPMGATFKETIAE
VRRRVHNLVSFQIDIGHGTMDYTEVKEEDWATAWKSFYHPVQVTEQVTIVPTWEEYSARPGEIVIELDPGMAFGTGTHPT
TILSLQALEQAVKQGDAVIDVGTGSGILAIAAWKFGAESITALDLDEVAVNSAKANVALNSASDFVHVQQGNLLDDVASE
SADVLVSNILAEVILQFTADAYRVVKRGGLFLTSGIISSKREAVEGALKAVGFLIQEVNELDDWVAIVAQKPSQA

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=315, Percent_Identity=32.0634920634921, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_BACSK (Q5WHF9)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175157.1
- ProteinModelPortal:   Q5WHF9
- SMR:   Q5WHF9
- STRING:   Q5WHF9
- EnsemblBacteria:   EBBACT00000049533
- GeneID:   3201284
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1661
- NMPDR:   fig|66692.3.peg.44
- eggNOG:   COG2264
- GeneTree:   EBGT00050000002784
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- BioCyc:   BCLA66692:ABC1661-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34294; Mature: 34294

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWAEFRVHTTQEAVEPVSNILHELGAAGVAIEDPQDLVTEWSVKYGEVYELSPEDYPDE
CCCCCEEEECHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHCCCCCCEEECCCCCCCCC
GVMVKAYFPMGATFKETIAEVRRRVHNLVSFQIDIGHGTMDYTEVKEEDWATAWKSFYHP
CEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
VQVTEQVTIVPTWEEYSARPGEIVIELDPGMAFGTGTHPTTILSLQALEQAVKQGDAVID
EEECCEEEEEECHHHHCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCEEEE
VGTGSGILAIAAWKFGAESITALDLDEVAVNSAKANVALNSASDFVHVQQGNLLDDVASE
ECCCCCEEEEEEECCCCCCEEEECHHHHHHCCCCCEEEEECCCCEEEEECCCHHHHHHHH
SADVLVSNILAEVILQFTADAYRVVKRGGLFLTSGIISSKREAVEGALKAVGFLIQEVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDWVAIVAQKPSQA
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MKWAEFRVHTTQEAVEPVSNILHELGAAGVAIEDPQDLVTEWSVKYGEVYELSPEDYPDE
CCCCCEEEECHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHCCCCCCEEECCCCCCCCC
GVMVKAYFPMGATFKETIAEVRRRVHNLVSFQIDIGHGTMDYTEVKEEDWATAWKSFYHP
CEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHCCC
VQVTEQVTIVPTWEEYSARPGEIVIELDPGMAFGTGTHPTTILSLQALEQAVKQGDAVID
EEECCEEEEEECHHHHCCCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCCEEEE
VGTGSGILAIAAWKFGAESITALDLDEVAVNSAKANVALNSASDFVHVQQGNLLDDVASE
ECCCCCEEEEEEECCCCCCEEEECHHHHHHCCCCCEEEEECCCCEEEEECCCHHHHHHHH
SADVLVSNILAEVILQFTADAYRVVKRGGLFLTSGIISSKREAVEGALKAVGFLIQEVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDWVAIVAQKPSQA
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA