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The map label for this gene is cymR [H]

Identifier: 56963349

GI number: 56963349

Start: 1708937

End: 1709356

Strand: Direct

Name: cymR [H]

Synonym: ABC1584

Alternate gene names: 56963349

Gene position: 1708937-1709356 (Clockwise)

Preceding gene: 56963346

Following gene: 56963350

Centisome position: 39.71

GC content: 42.62

Gene sequence:

>420_bases
GTGAAAATTTCGACAAAAGGACGTTATGGATTGACGATTATGATGGCACTCGCTAAGAAATCAGGGGAAGGGCCTGTTTC
CTTGAAATCTATTGCTAAGGAATATAAACTATCAGAGCATTATTTGGAGCAATTGATTGCGCCGCTCCGCAATGCGATGC
TCGTTAAAAGTGTTCGCGGTGCCTATGGTGGCTATATGCTGGCTAAAGATGCCGAAGATATTACAGCAGGCGATATTATT
CGTGTGTTAGAAGGACCGATTAGTCCGGTTGAAGTGCTTGAAGATGAGGAGCCTGCCAAGCGCGATTTATGGATAAAAAT
ACGGGACGCAGTCAAGGAAGTGCTCGATAAAACGACTCTTGCCGACTTAGCCAATTTTAAGGAAGATGGAGAACAAGAGT
ACTATATGTTTTATATTTAA

Upstream 100 bases:

>100_bases
TGAAAAGCGGATCACGAGAACGGATTGTCACATACATGAAGTGAAAGACGGAGTATTTTCCAGATCATACAGCATTTATT
TTGATGAAAGAGGGATTGAC

Downstream 100 bases:

>100_bases
CAAAACGGAGCAAGGGGACGGAAGGTGCCACTCATGAAGCAAATTTATTTAGACCATGCAGCCACATCAGTGTTGCATCC
CCAAGCGTTGGAAGCGATGA

Product: transcriptional regulator

Products: NA

Alternate protein names: Cysteine metabolism repressor [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MKISTKGRYGLTIMMALAKKSGEGPVSLKSIAKEYKLSEHYLEQLIAPLRNAMLVKSVRGAYGGYMLAKDAEDITAGDII
RVLEGPISPVEVLEDEEPAKRDLWIKIRDAVKEVLDKTTLADLANFKEDGEQEYYMFYI

Sequences:

>Translated_139_residues
MKISTKGRYGLTIMMALAKKSGEGPVSLKSIAKEYKLSEHYLEQLIAPLRNAMLVKSVRGAYGGYMLAKDAEDITAGDII
RVLEGPISPVEVLEDEEPAKRDLWIKIRDAVKEVLDKTTLADLANFKEDGEQEYYMFYI
>Mature_139_residues
MKISTKGRYGLTIMMALAKKSGEGPVSLKSIAKEYKLSEHYLEQLIAPLRNAMLVKSVRGAYGGYMLAKDAEDITAGDII
RVLEGPISPVEVLEDEEPAKRDLWIKIRDAVKEVLDKTTLADLANFKEDGEQEYYMFYI

Specific function: Master repressor of cysteine metabolism in B.subtilis. Controls the expression of genes involved either in cysteine synthesis from sulfide (cysK), sulfonates (ssu), or methionine (mccAB) or in cystine uptake (tcyP). Activity of CymR is positively regulate

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=134, Percent_Identity=35.0746268656716, Blast_Score=83, Evalue=8e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000944 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 15618; Mature: 15618

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISTKGRYGLTIMMALAKKSGEGPVSLKSIAKEYKLSEHYLEQLIAPLRNAMLVKSVRG
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGGYMLAKDAEDITAGDIIRVLEGPISPVEVLEDEEPAKRDLWIKIRDAVKEVLDKTTL
HHCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
ADLANFKEDGEQEYYMFYI
HHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKISTKGRYGLTIMMALAKKSGEGPVSLKSIAKEYKLSEHYLEQLIAPLRNAMLVKSVRG
CCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYGGYMLAKDAEDITAGDIIRVLEGPISPVEVLEDEEPAKRDLWIKIRDAVKEVLDKTTL
HHCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
ADLANFKEDGEQEYYMFYI
HHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]