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The map label for this gene is nadA

Identifier: 56963314

GI number: 56963314

Start: 1672390

End: 1673484

Strand: Direct

Name: nadA

Synonym: ABC1549

Alternate gene names: 56963314

Gene position: 1672390-1673484 (Clockwise)

Preceding gene: 56963313

Following gene: 56963315

Centisome position: 38.86

GC content: 48.22

Gene sequence:

>1095_bases
ATGCAAGTAATGCAACCAGCGAGATTGCCCCATCACTATCGGGAAATGTCAAGTGCTGAAAAAGAAGCCCGTATTCGCGA
AGCAAAAGCATTTTTTGGCAATGACCTACTCATACCAGGCCACCATTACCAGCGAGAGGACGTCATCCAATTTGCTGACT
TCACCGGCGATTCATTGCAACTTGCGCAACTGTGCGGCCAAACGTCATCGGCCAATATCGTTTTTTGCGGTGTTCACTTT
ATGGCGGAGACAGCAGACATGCTAACGAGTCGAGAGCAGCATGTGATCCTGCCTGATCTTGCCGCTGGCTGTTCGATGGC
CGATATGGCTTCGATCGCCCAAACAGAGCGTGCTTGGGAAGCGCTGACGGAACGATTCGGAGACACGATTTTGCCGCTGA
CGTATGTCAACAGCACCGCTGAAATTAAAGCGTTTTGCGGACGCCATGGTGGCGCATGCGTAACGTCATCAAACGCTAAA
AACATGGTGCAGTGGGCGTTTGCTCAAAAGCCAAGGGTAATGTTCTTGCCTGACCAACACCTGGGGAGAAACACAGCTTT
TGCACTTGGGATTCCTTTAGAAAAAATGGCGGTCTGGAATCCTCATACACATGAACTCGAGCTCCTCCCTGGTGCGAACA
TAGAAGAAATCATCGTCATTTTATGGAAAGGGCACTGCTCTGTTCATGAAAAATTTACAGTTGAGCAAATTAAAAACGTG
CGTGACCGCTCTCCGCATACACAAGTGATTGTTCATCCAGAGTGCACACACGAAGTTGTGCAAGCTGCTGATAAAGCCGG
GAGCACACACTACATTATTGAAACATTAAAACAGGCGGAGCCAGGAACATCCTGGGCAATTGGGACGGAAATGAATTTGG
TCAATCGTTTAGCGAAACAGCATCCGGATAAGCAAGTGTTTTCTCTTCACTCAACTATGTGCCTTTGTTTAACAATGAAC
CGCATTGATTTGGATCATCTTGCTTGGTCACTGGATTTGCTGCGTGAAGGCAAACGCCAATTTGAAATTACGGTCGCCGA
AGATGTCGCAGCGGAAGCAAGAACGGCTTTAGCGCGGATGCTGGCAACAGTTTAA

Upstream 100 bases:

>100_bases
AATTTGCCAATACTGGCGTTGATTTTCTGTCGCTTGGATTTTTGACACATTCAGTTGTTGCACTCGATTTGAGCATGCTT
ATACAAAAGGGGGAAGGACA

Downstream 100 bases:

>100_bases
AGTTTAATGATTGGAGCGACAACCTAAAAGAGCGTACAGTGGATTGCTCTTTTAGGTTTGTAAACGCTCTGTATACTTTA
CACTGTGAAACGAGCGTTTT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MQVMQPARLPHHYREMSSAEKEARIREAKAFFGNDLLIPGHHYQREDVIQFADFTGDSLQLAQLCGQTSSANIVFCGVHF
MAETADMLTSREQHVILPDLAAGCSMADMASIAQTERAWEALTERFGDTILPLTYVNSTAEIKAFCGRHGGACVTSSNAK
NMVQWAFAQKPRVMFLPDQHLGRNTAFALGIPLEKMAVWNPHTHELELLPGANIEEIIVILWKGHCSVHEKFTVEQIKNV
RDRSPHTQVIVHPECTHEVVQAADKAGSTHYIIETLKQAEPGTSWAIGTEMNLVNRLAKQHPDKQVFSLHSTMCLCLTMN
RIDLDHLAWSLDLLREGKRQFEITVAEDVAAEARTALARMLATV

Sequences:

>Translated_364_residues
MQVMQPARLPHHYREMSSAEKEARIREAKAFFGNDLLIPGHHYQREDVIQFADFTGDSLQLAQLCGQTSSANIVFCGVHF
MAETADMLTSREQHVILPDLAAGCSMADMASIAQTERAWEALTERFGDTILPLTYVNSTAEIKAFCGRHGGACVTSSNAK
NMVQWAFAQKPRVMFLPDQHLGRNTAFALGIPLEKMAVWNPHTHELELLPGANIEEIIVILWKGHCSVHEKFTVEQIKNV
RDRSPHTQVIVHPECTHEVVQAADKAGSTHYIIETLKQAEPGTSWAIGTEMNLVNRLAKQHPDKQVFSLHSTMCLCLTMN
RIDLDHLAWSLDLLREGKRQFEITVAEDVAAEARTALARMLATV
>Mature_364_residues
MQVMQPARLPHHYREMSSAEKEARIREAKAFFGNDLLIPGHHYQREDVIQFADFTGDSLQLAQLCGQTSSANIVFCGVHF
MAETADMLTSREQHVILPDLAAGCSMADMASIAQTERAWEALTERFGDTILPLTYVNSTAEIKAFCGRHGGACVTSSNAK
NMVQWAFAQKPRVMFLPDQHLGRNTAFALGIPLEKMAVWNPHTHELELLPGANIEEIIVILWKGHCSVHEKFTVEQIKNV
RDRSPHTQVIVHPECTHEVVQAADKAGSTHYIIETLKQAEPGTSWAIGTEMNLVNRLAKQHPDKQVFSLHSTMCLCLTMN
RIDLDHLAWSLDLLREGKRQFEITVAEDVAAEARTALARMLATV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=336, Percent_Identity=25.5952380952381, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA_BACSK (Q5WHS1)

Other databases:

- EMBL:   AP006627
- RefSeq:   YP_175045.1
- HSSP:   O57767
- ProteinModelPortal:   Q5WHS1
- SMR:   Q5WHS1
- STRING:   Q5WHS1
- EnsemblBacteria:   EBBACT00000047122
- GeneID:   3204504
- GenomeReviews:   AP006627_GR
- KEGG:   bcl:ABC1549
- NMPDR:   fig|66692.3.peg.1511
- eggNOG:   COG0379
- GeneTree:   EBGT00050000002444
- HOGENOM:   HBG291157
- OMA:   GTELNLV
- ProtClustDB:   PRK09375
- BioCyc:   BCLA66692:ABC1549-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00569
- InterPro:   IPR003473
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 40685; Mature: 40685

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: BINDING 41-41 BINDING 58-58 BINDING 135-135 BINDING 156-156 BINDING 252-252 BINDING 269-269

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVMQPARLPHHYREMSSAEKEARIREAKAFFGNDLLIPGHHYQREDVIQFADFTGDSLQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCHH
LAQLCGQTSSANIVFCGVHFMAETADMLTSREQHVILPDLAAGCSMADMASIAQTERAWE
HHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEECCCHHCCCCHHHHHHHHHHHHHHH
ALTERFGDTILPLTYVNSTAEIKAFCGRHGGACVTSSNAKNMVQWAFAQKPRVMFLPDQH
HHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCEEEECCCHH
LGRNTAFALGIPLEKMAVWNPHTHELELLPGANIEEIIVILWKGHCSVHEKFTVEQIKNV
CCCCCEEEECCCHHHHEECCCCCCEEEECCCCCHHHEEEEEECCCCCCCHHCCHHHHHHH
RDRSPHTQVIVHPECTHEVVQAADKAGSTHYIIETLKQAEPGTSWAIGTEMNLVNRLAKQ
HCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
HPDKQVFSLHSTMCLCLTMNRIDLDHLAWSLDLLREGKRQFEITVAEDVAAEARTALARM
CCCHHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHH
LATV
HHCC
>Mature Secondary Structure
MQVMQPARLPHHYREMSSAEKEARIREAKAFFGNDLLIPGHHYQREDVIQFADFTGDSLQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCHH
LAQLCGQTSSANIVFCGVHFMAETADMLTSREQHVILPDLAAGCSMADMASIAQTERAWE
HHHHCCCCCCCCEEEEEHHHHHHHHHHHHCCCCEEECCCHHCCCCHHHHHHHHHHHHHHH
ALTERFGDTILPLTYVNSTAEIKAFCGRHGGACVTSSNAKNMVQWAFAQKPRVMFLPDQH
HHHHHHCCCEEEEEECCCHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCEEEECCCHH
LGRNTAFALGIPLEKMAVWNPHTHELELLPGANIEEIIVILWKGHCSVHEKFTVEQIKNV
CCCCCEEEECCCHHHHEECCCCCCEEEECCCCCHHHEEEEEECCCCCCCHHCCHHHHHHH
RDRSPHTQVIVHPECTHEVVQAADKAGSTHYIIETLKQAEPGTSWAIGTEMNLVNRLAKQ
HCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
HPDKQVFSLHSTMCLCLTMNRIDLDHLAWSLDLLREGKRQFEITVAEDVAAEARTALARM
CCCHHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHH
LATV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA