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The map label for this gene is cssR [H]

Identifier: 56963288

GI number: 56963288

Start: 1645567

End: 1646247

Strand: Direct

Name: cssR [H]

Synonym: ABC1523

Alternate gene names: 56963288

Gene position: 1645567-1646247 (Clockwise)

Preceding gene: 56963287

Following gene: 56963289

Centisome position: 38.23

GC content: 43.32

Gene sequence:

>681_bases
ATGGAAACATATAATATTTACCTAGTAGAAGATGAAGCGAATTTATCAGAGGTATTAAAGGCTTATTTGCAAAAGGAAGG
ATGGAACGTCACCGTTTTTCTCGACGGCAATGCTGCTATTGAGGCGGTCCCGGATAAACCGCATTTGTGGGTATTGGATA
TTATGTTGCCTGGGACCGACGGCTACCAAGTTTTGAAAGCTATTAAAGAGCAAGAAGACACGCCAGTTATTTTCATTTCT
GCACGTGACCAAGACTTAGATCGTGTGCTTGGTCTTGAGATGGGCAGCGATGATTATTTGGCAAAGCCGTTTTTGCCACA
GGAACTGATTATCCGTGTAAAAAAGCTGCTTAATCGTGTTTACGGTACGTCGTCAGCAGAATCGCAAAAAATTGAGCTGA
ACAACTACAGCATTGACCCAATCGGCCGCACGATTGTCGATCTAGAGGCCAATAATGACACGGTTGATTTAACGACAAAA
GAAATGGATTTAATGTTGCTGTTGTCTGCTGATATTGGCAAGGCGTTTTCTCGGGAAAAAATCATTGAGCATGTTTGGGG
CGAAAATTATTTTGGTTCAGAACGGGCAGTGGACGATGTAGTCCGCCGCGTCCGTAAAAAAATGCCGCGTATCCACTTAG
AAACGCTCTATGGTTACGGATACCGCATTTTGTCTTCATGA

Upstream 100 bases:

>100_bases
CCTGTTTATGGGCAGGTAACTGAAAGTGAAAACCTAAAGAGGACAAGCTTTTAGACACAATTGTAGATGAAATTGACTGG
AGCTGTTAGGAGGATTGCAG

Downstream 100 bases:

>100_bases
TTAAAATCAACTTGACGAAACGAATATGGCTAGCATTCGTTTCGTTAATTGTGCTTGTTGTCCTTTCGATTACCATTGTT
TACCCACTTTCGATCAGAGG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
METYNIYLVEDEANLSEVLKAYLQKEGWNVTVFLDGNAAIEAVPDKPHLWVLDIMLPGTDGYQVLKAIKEQEDTPVIFIS
ARDQDLDRVLGLEMGSDDYLAKPFLPQELIIRVKKLLNRVYGTSSAESQKIELNNYSIDPIGRTIVDLEANNDTVDLTTK
EMDLMLLLSADIGKAFSREKIIEHVWGENYFGSERAVDDVVRRVRKKMPRIHLETLYGYGYRILSS

Sequences:

>Translated_226_residues
METYNIYLVEDEANLSEVLKAYLQKEGWNVTVFLDGNAAIEAVPDKPHLWVLDIMLPGTDGYQVLKAIKEQEDTPVIFIS
ARDQDLDRVLGLEMGSDDYLAKPFLPQELIIRVKKLLNRVYGTSSAESQKIELNNYSIDPIGRTIVDLEANNDTVDLTTK
EMDLMLLLSADIGKAFSREKIIEHVWGENYFGSERAVDDVVRRVRKKMPRIHLETLYGYGYRILSS
>Mature_226_residues
METYNIYLVEDEANLSEVLKAYLQKEGWNVTVFLDGNAAIEAVPDKPHLWVLDIMLPGTDGYQVLKAIKEQEDTPVIFIS
ARDQDLDRVLGLEMGSDDYLAKPFLPQELIIRVKKLLNRVYGTSSAESQKIELNNYSIDPIGRTIVDLEANNDTVDLTTK
EMDLMLLLSADIGKAFSREKIIEHVWGENYFGSERAVDDVVRRVRKKMPRIHLETLYGYGYRILSS

Specific function: Member of the two-component regulatory system CssS/CssR required to control the cellular response to secretion stress [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=34.3612334801762, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=34.070796460177, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=35.9307359307359, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=32.4894514767932, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=33.3333333333333, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=29.7413793103448, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=31.304347826087, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=30.3571428571429, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI145693140, Length=214, Percent_Identity=30.3738317757009, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=29.5154185022026, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=30.0448430493274, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=30.6666666666667, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=28.4444444444444, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790299, Length=145, Percent_Identity=31.7241379310345, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25787; Mature: 25787

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METYNIYLVEDEANLSEVLKAYLQKEGWNVTVFLDGNAAIEAVPDKPHLWVLDIMLPGTD
CCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEEEEECCCC
GYQVLKAIKEQEDTPVIFISARDQDLDRVLGLEMGSDDYLAKPFLPQELIIRVKKLLNRV
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
YGTSSAESQKIELNNYSIDPIGRTIVDLEANNDTVDLTTKEMDLMLLLSADIGKAFSREK
HCCCCCCCCEEEECCEEECCCCCEEEEEECCCCEEEEEECCEEEEEEEECCHHHHHHHHH
IIEHVWGENYFGSERAVDDVVRRVRKKMPRIHLETLYGYGYRILSS
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHCCCEEEECC
>Mature Secondary Structure
METYNIYLVEDEANLSEVLKAYLQKEGWNVTVFLDGNAAIEAVPDKPHLWVLDIMLPGTD
CCEEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCEEEEEEEECCCC
GYQVLKAIKEQEDTPVIFISARDQDLDRVLGLEMGSDDYLAKPFLPQELIIRVKKLLNRV
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
YGTSSAESQKIELNNYSIDPIGRTIVDLEANNDTVDLTTKEMDLMLLLSADIGKAFSREK
HCCCCCCCCEEEECCEEECCCCCEEEEEECCCCEEEEEECCEEEEEEEECCHHHHHHHHH
IIEHVWGENYFGSERAVDDVVRRVRKKMPRIHLETLYGYGYRILSS
HHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEEEHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9639930; 9384377; 11555295 [H]