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The map label for this gene is nagA [H]

Identifier: 56963254

GI number: 56963254

Start: 1609607

End: 1610794

Strand: Direct

Name: nagA [H]

Synonym: ABC1489

Alternate gene names: 56963254

Gene position: 1609607-1610794 (Clockwise)

Preceding gene: 56963249

Following gene: 56963255

Centisome position: 37.4

GC content: 47.47

Gene sequence:

>1188_bases
ATGGCAAGTATCGTTGTAACAGGGGGGCAGTTGATCACAGGGGAACCAGGGTGTCGTAAATACGAGAAAGGTTTTCTTGC
AATCGACAATGGCAAAATTACCGCGGTCGGTGTTGGCGACGGCGCCGATTATAAGAATAAAGATACAGTCCAGATAACGG
TTCCAGCTGATGCCGTTGTTGTCCCAGGCTTTGTTGACGTGCACATACATGGCGGCTATGGTGCCGATGTAATGGACCGT
ACAAAGGATGCGTTGCAAACAATGGCAGCAAACTTGCCAGCCGAAGGGACGACCGCTTTTCTTGCGACAACCATTACCCA
AAAACATGAGGACATTGAAGCTGCGATTGAAAATGTAGTCGCTTATAGACGGGCGGATAAAGAAGCAGAGATTGTCGGCC
TACATATTGAAGGGCCTTTTATTAATGAAACGAAAAAAGGCGCACAGCCTCTCGAGTACATTGTAGAACCATCCGTACCA
ATCATGAAAAAATGGATCGATTTAGCAAAAGGCATGATTAAACAAGTAACCTACGCACCGGAAAAACGAAATGGAAGTGA
GTTGGCAGCCTATTTGCGTTCAGAAGGTGCGAATCCGTCAATTGGCCATTCAGATGCTGTCTATACTGAAATGGAGCAAG
CTGTCGCAGCAGGTGCAAACCAAGTTACGCATATGTACAATGGCATGCGTCCTTTGCATCATCGTGAACCAGGTGTAGCT
GGTGGGGCGCTCCTCCTTGATGAACTCGACATTGAATTGATTGTAGACGGCATTCACATCCATCCAGAAATGGTGAAGCT
GGCCTGGAAAGCAAAGGGCACAGACCAATGTCTACTTATTACTGACTCGATGAGGGCAAAAGGGTTGCCTGACGGTGCTT
ATGATTTAGGGGGACAGGACGTTTCTGTTAACGGTGGAAGAGCGACGCTTTCTGATGGCACGCTCGCCGGTTCTGTTTTG
CAAATGAACAAGGCGGTAGCAAATATGGTTGCTTATACTGGCTGCTCATTGGAACAAGCGGTGCAAATGGCTTCCTACAA
CCCAGCGAAAAAAATTGGCATTGACGCGAAAAAAGGGTCATTGGTGCCTGGGAAAGATGGCGATTTTACTGTGCTCACGA
AAGAGGGCGACGTGTTGTACACCTACTGTTTAGGGAAAAAAGCATATGGCAAGGAGGATGACGTATGA

Upstream 100 bases:

>100_bases
ACCATAACTTTTTTTTCGTTGTAATTGGTATAGACAACTAAACGACTAGAGCGTATACTAAAAGAAACAAAGGGAATGAT
GAAACGAGGAAGGTGATCGC

Downstream 100 bases:

>100_bases
ATATTATTCACGTAAAAAATTATGAAGAAATGAGCCAAAAAGCAGCAGCACTCTTGTTTGAGCGAATTCAGCAGTCTCCG
AAAATAACGCTCGGACTTGC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MASIVVTGGQLITGEPGCRKYEKGFLAIDNGKITAVGVGDGADYKNKDTVQITVPADAVVVPGFVDVHIHGGYGADVMDR
TKDALQTMAANLPAEGTTAFLATTITQKHEDIEAAIENVVAYRRADKEAEIVGLHIEGPFINETKKGAQPLEYIVEPSVP
IMKKWIDLAKGMIKQVTYAPEKRNGSELAAYLRSEGANPSIGHSDAVYTEMEQAVAAGANQVTHMYNGMRPLHHREPGVA
GGALLLDELDIELIVDGIHIHPEMVKLAWKAKGTDQCLLITDSMRAKGLPDGAYDLGGQDVSVNGGRATLSDGTLAGSVL
QMNKAVANMVAYTGCSLEQAVQMASYNPAKKIGIDAKKGSLVPGKDGDFTVLTKEGDVLYTYCLGKKAYGKEDDV

Sequences:

>Translated_395_residues
MASIVVTGGQLITGEPGCRKYEKGFLAIDNGKITAVGVGDGADYKNKDTVQITVPADAVVVPGFVDVHIHGGYGADVMDR
TKDALQTMAANLPAEGTTAFLATTITQKHEDIEAAIENVVAYRRADKEAEIVGLHIEGPFINETKKGAQPLEYIVEPSVP
IMKKWIDLAKGMIKQVTYAPEKRNGSELAAYLRSEGANPSIGHSDAVYTEMEQAVAAGANQVTHMYNGMRPLHHREPGVA
GGALLLDELDIELIVDGIHIHPEMVKLAWKAKGTDQCLLITDSMRAKGLPDGAYDLGGQDVSVNGGRATLSDGTLAGSVL
QMNKAVANMVAYTGCSLEQAVQMASYNPAKKIGIDAKKGSLVPGKDGDFTVLTKEGDVLYTYCLGKKAYGKEDDV
>Mature_394_residues
ASIVVTGGQLITGEPGCRKYEKGFLAIDNGKITAVGVGDGADYKNKDTVQITVPADAVVVPGFVDVHIHGGYGADVMDRT
KDALQTMAANLPAEGTTAFLATTITQKHEDIEAAIENVVAYRRADKEAEIVGLHIEGPFINETKKGAQPLEYIVEPSVPI
MKKWIDLAKGMIKQVTYAPEKRNGSELAAYLRSEGANPSIGHSDAVYTEMEQAVAAGANQVTHMYNGMRPLHHREPGVAG
GALLLDELDIELIVDGIHIHPEMVKLAWKAKGTDQCLLITDSMRAKGLPDGAYDLGGQDVSVNGGRATLSDGTLAGSVLQ
MNKAVANMVAYTGCSLEQAVQMASYNPAKKIGIDAKKGSLVPGKDGDFTVLTKEGDVLYTYCLGKKAYGKEDDV

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=373, Percent_Identity=31.3672922252011, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI224922791, Length=377, Percent_Identity=31.5649867374005, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI1786892, Length=336, Percent_Identity=31.25, Blast_Score=154, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI17553768, Length=367, Percent_Identity=32.6975476839237, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI19920392, Length=342, Percent_Identity=33.3333333333333, Blast_Score=181, Evalue=7e-46,
Organism=Drosophila melanogaster, GI281361140, Length=354, Percent_Identity=32.7683615819209, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 42002; Mature: 41871

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIVVTGGQLITGEPGCRKYEKGFLAIDNGKITAVGVGDGADYKNKDTVQITVPADAVV
CCEEEEECCEEEECCCCCHHHHCCEEEECCCEEEEEECCCCCCCCCCCEEEEEECCCEEE
VPGFVDVHIHGGYGADVMDRTKDALQTMAANLPAEGTTAFLATTITQKHEDIEAAIENVV
ECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
AYRRADKEAEIVGLHIEGPFINETKKGAQPLEYIVEPSVPIMKKWIDLAKGMIKQVTYAP
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
EKRNGSELAAYLRSEGANPSIGHSDAVYTEMEQAVAAGANQVTHMYNGMRPLHHREPGVA
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
GGALLLDELDIELIVDGIHIHPEMVKLAWKAKGTDQCLLITDSMRAKGLPDGAYDLGGQD
CCEEEEECCCEEEEEECEEECHHHHEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCE
VSVNGGRATLSDGTLAGSVLQMNKAVANMVAYTGCSLEQAVQMASYNPAKKIGIDAKKGS
EEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHCCCCCCCCC
LVPGKDGDFTVLTKEGDVLYTYCLGKKAYGKEDDV
CCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ASIVVTGGQLITGEPGCRKYEKGFLAIDNGKITAVGVGDGADYKNKDTVQITVPADAVV
CEEEEECCEEEECCCCCHHHHCCEEEECCCEEEEEECCCCCCCCCCCEEEEEECCCEEE
VPGFVDVHIHGGYGADVMDRTKDALQTMAANLPAEGTTAFLATTITQKHEDIEAAIENVV
ECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHH
AYRRADKEAEIVGLHIEGPFINETKKGAQPLEYIVEPSVPIMKKWIDLAKGMIKQVTYAP
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
EKRNGSELAAYLRSEGANPSIGHSDAVYTEMEQAVAAGANQVTHMYNGMRPLHHREPGVA
CCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
GGALLLDELDIELIVDGIHIHPEMVKLAWKAKGTDQCLLITDSMRAKGLPDGAYDLGGQD
CCEEEEECCCEEEEEECEEECHHHHEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCE
VSVNGGRATLSDGTLAGSVLQMNKAVANMVAYTGCSLEQAVQMASYNPAKKIGIDAKKGS
EEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHCCCCCCCCC
LVPGKDGDFTVLTKEGDVLYTYCLGKKAYGKEDDV
CCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]