BacMap

Definition	Bacillus clausii KSM-K16, complete genome.
Accession	NC_006582
Length	4,303,871

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The map label for this gene is fabL [H]

Identifier: 56963085

GI number: 56963085

Start: 1431047

End: 1431796

Strand: Direct

Name: fabL [H]

Synonym: ABC1313

Alternate gene names: 56963085

Gene position: 1431047-1431796 (Clockwise)

Preceding gene: 56963082

Following gene: 56963086

Centisome position: 33.25

GC content: 48.0

Gene sequence:

>750_bases
ATGGAAAAGAAAGTGGCATTAGTGACAGGAAGCAGCCGCGGAATCGGAAAAGAAATCGCGATTTCCCTGGCAAAAGAAGG
ATATAACCTCGTAATCAATTACGCACGAAGCCGCTCGAACGCAGAAGCAACAGCAGCGGAAATTCGCGCACTTGGCGTGG
ACGTGCTTGTTGTCAAAGCCAATGTTGGCAAGCAGGAAAAAATTAAAGCGATGTTTGAACAAATTGACGACACTTTCGGG
CGTCTTGATGTGTTTGTAAACAACGCAGCTTCTGGTGTGTTACGGCCGCTGATGGAGCTTGAAGAAAGCCATTGGGATTG
GACGATGGATATTAACGCCAAAGCACTGCTATTTTGTGCCCAAGAAGCGGCAAAAAGAATGGAAAAAACCGGAGGCGGCA
AAATTGTCAGCCTAAGTTCTTTAGGGGCCATCCGTTATTTGGAGAATTATACGACCGTTGGCGTGTCTAAAGCGGCTGTA
GAATCATTAACGCGCTATTTGGCTGTTGAACTGGCGCCAAAAGGAATTGCCGTCAATGCTGTTTCGGGTGGAGCAGTGGA
CACAGATGCATTGACACACTTTCCAAACCGGGATGAATTGCTAAAGGATGCAGCAGAGCGGACTCCTGCAGGGCGGATCG
TAGAACCAAAGGACCTTGCCAAAGCGGCCATGTTTTTATTGTCAGATGAAGCAAGTATGATTCGCGGCCAAACGATTATC
GTGGATGGCGGTATCTCCTTGCTGGCATAA

Upstream 100 bases:

>100_bases
AATGCTCCTTTCCTGTGCTTTCGTGTAGTTTGGCTGTTCGAGCGCCTGCCTATGCGTTATAATGGATAAATCGTACTGAC
TTAGCAAGGAGCGTGTAGAC

Downstream 100 bases:

>100_bases
CGTTTTATTTTTTTTTGCATAGAAAAAAACTCCACGGGAAAAGTATATAGCGTGGAGGTGATAAACCATGGACAAAGCAT
CAAAAACAAACAAAAACCAA

Product: enoyl-(acyl carrier protein) reductase

Products: NA

Alternate protein names: Enoyl-acyl carrier protein reductase III; NADPH-dependent enoyl-ACP reductase [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MEKKVALVTGSSRGIGKEIAISLAKEGYNLVINYARSRSNAEATAAEIRALGVDVLVVKANVGKQEKIKAMFEQIDDTFG
RLDVFVNNAASGVLRPLMELEESHWDWTMDINAKALLFCAQEAAKRMEKTGGGKIVSLSSLGAIRYLENYTTVGVSKAAV
ESLTRYLAVELAPKGIAVNAVSGGAVDTDALTHFPNRDELLKDAAERTPAGRIVEPKDLAKAAMFLLSDEASMIRGQTII
VDGGISLLA

Sequences:

>Translated_249_residues
MEKKVALVTGSSRGIGKEIAISLAKEGYNLVINYARSRSNAEATAAEIRALGVDVLVVKANVGKQEKIKAMFEQIDDTFG
RLDVFVNNAASGVLRPLMELEESHWDWTMDINAKALLFCAQEAAKRMEKTGGGKIVSLSSLGAIRYLENYTTVGVSKAAV
ESLTRYLAVELAPKGIAVNAVSGGAVDTDALTHFPNRDELLKDAAERTPAGRIVEPKDLAKAAMFLLSDEASMIRGQTII
VDGGISLLA
>Mature_249_residues
MEKKVALVTGSSRGIGKEIAISLAKEGYNLVINYARSRSNAEATAAEIRALGVDVLVVKANVGKQEKIKAMFEQIDDTFG
RLDVFVNNAASGVLRPLMELEESHWDWTMDINAKALLFCAQEAAKRMEKTGGGKIVSLSSLGAIRYLENYTTVGVSKAAV
ESLTRYLAVELAPKGIAVNAVSGGAVDTDALTHFPNRDELLKDAAERTPAGRIVEPKDLAKAAMFLLSDEASMIRGQTII
VDGGISLLA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=245, Percent_Identity=35.1020408163265, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=31.4516129032258, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI209862901, Length=211, Percent_Identity=33.6492890995261, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI19923983, Length=211, Percent_Identity=33.6492890995261, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=33.1983805668016, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=28.7937743190661, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=31.9838056680162, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI7705925, Length=240, Percent_Identity=30.8333333333333, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=35.7142857142857, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI10190704, Length=246, Percent_Identity=28.4552845528455, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI66933014, Length=255, Percent_Identity=27.4509803921569, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI109715829, Length=240, Percent_Identity=30.4166666666667, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI15277342, Length=258, Percent_Identity=28.2945736434109, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=33.160621761658, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI31542939, Length=243, Percent_Identity=26.3374485596708, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI302344755, Length=103, Percent_Identity=39.8058252427184, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI4503301, Length=210, Percent_Identity=27.1428571428571, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI223718074, Length=200, Percent_Identity=30, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254986, Length=185, Percent_Identity=27.5675675675676, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789208, Length=252, Percent_Identity=35.3174603174603, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=33.6032388663968, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790717, Length=239, Percent_Identity=30.9623430962343, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=31.4285714285714, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=33.2, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=34.136546184739, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082100, Length=251, Percent_Identity=31.4741035856574, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=29.0983606557377, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787545, Length=261, Percent_Identity=30.2681992337165, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=30.5785123966942, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789378, Length=249, Percent_Identity=27.3092369477912, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=28.957528957529, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=24.0157480314961, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787526, Length=253, Percent_Identity=24.1106719367589, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=36.0655737704918, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=31.6205533596838, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=33.7164750957854, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=34.0909090909091, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=34.3396226415094, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=33.7121212121212, Blast_Score=110, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=31.3432835820896, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=30.5343511450382, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=32.6693227091633, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=31.2, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=31.8007662835249, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=29.6992481203008, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=31.5384615384615, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17555612, Length=217, Percent_Identity=33.1797235023041, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=31.6981132075472, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17538480, Length=262, Percent_Identity=29.0076335877863, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=30.5019305019305, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=251, Percent_Identity=31.8725099601594, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=31.8518518518519, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=31.4516129032258, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=30.9433962264151, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=31.4393939393939, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71997099, Length=210, Percent_Identity=30.4761904761905, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI86565303, Length=214, Percent_Identity=30.8411214953271, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=28.8, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=29.2307692307692, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=29.277566539924, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=27.0161290322581, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561272, Length=260, Percent_Identity=30, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982365, Length=186, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=26.0700389105058, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=29.3193717277487, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193207185, Length=149, Percent_Identity=34.2281879194631, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=25.9109311740891, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322067, Length=190, Percent_Identity=28.9473684210526, Blast_Score=63, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=194, Percent_Identity=25.7731958762887, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=33.1967213114754, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=34.8, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=35.2, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=35.5731225296443, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=34.251968503937, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=30.5555555555556, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24644337, Length=175, Percent_Identity=33.7142857142857, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=30.1204819277108, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640492, Length=220, Percent_Identity=28.1818181818182, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357673, Length=245, Percent_Identity=22.8571428571429, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737361, Length=264, Percent_Identity=24.6212121212121, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=28.4210526315789, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI281364494, Length=241, Percent_Identity=26.1410788381743, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.10 [H]

Molecular weight: Translated: 26640; Mature: 26640

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKVALVTGSSRGIGKEIAISLAKEGYNLVINYARSRSNAEATAAEIRALGVDVLVVKA
CCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEHHCCCCCHHHHHHHHHHCEEEEEEEE
NVGKQEKIKAMFEQIDDTFGRLDVFVNNAASGVLRPLMELEESHWDWTMDINAKALLFCA
CCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHH
QEAAKRMEKTGGGKIVSLSSLGAIRYLENYTTVGVSKAAVESLTRYLAVELAPKGIAVNA
HHHHHHHHHCCCCCEEEEHHCCHHHHHHCCHHCCCHHHHHHHHHHHHHHEECCCCEEEEE
VSGGAVDTDALTHFPNRDELLKDAAERTPAGRIVEPKDLAKAAMFLLSDEASMIRGQTII
CCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCEEE
VDGGISLLA
EECCHHHCC
>Mature Secondary Structure
MEKKVALVTGSSRGIGKEIAISLAKEGYNLVINYARSRSNAEATAAEIRALGVDVLVVKA
CCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEHHCCCCCHHHHHHHHHHCEEEEEEEE
NVGKQEKIKAMFEQIDDTFGRLDVFVNNAASGVLRPLMELEESHWDWTMDINAKALLFCA
CCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHH
QEAAKRMEKTGGGKIVSLSSLGAIRYLENYTTVGVSKAAVESLTRYLAVELAPKGIAVNA
HHHHHHHHHCCCCCEEEEHHCCHHHHHHCCHHCCCHHHHHHHHHHHHHHEECCCCEEEEE
VSGGAVDTDALTHFPNRDELLKDAAERTPAGRIVEPKDLAKAAMFLLSDEASMIRGQTII
CCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCCCEEE
VDGGISLLA
EECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9202460; 9384377 [H]