| Definition | Bacillus clausii KSM-K16, complete genome. |
|---|---|
| Accession | NC_006582 |
| Length | 4,303,871 |
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The map label for this gene is hbdH1 [H]
Identifier: 56963082
GI number: 56963082
Start: 1429592
End: 1430341
Strand: Direct
Name: hbdH1 [H]
Synonym: ABC1310
Alternate gene names: 56963082
Gene position: 1429592-1430341 (Clockwise)
Preceding gene: 56963081
Following gene: 56963085
Centisome position: 33.22
GC content: 48.27
Gene sequence:
>750_bases ATGAATTTGGGCTTAACGGGAAAACGCGTATTCGTAACAGGAGGAACAAAAGGGATTGGCAAAGCAATTGCCAATGCTTT TGCTGCAGAAGGAGCCAAAGTGGCTGTTTGTGCAAGGGTGACAGAAGGCATAGAGGGACTACTAGCAGGTATTCAAACGA TTAGCGGCGATGTGACCAAAGCGGCTGAGCGTGAGCGAATGTTTGCTGAGGCGTCAGCAGCGATCGGACCGATTGACATA TTGGTTAACAATGCAGGCGGCAGCAATGGCGGAGCAATTTCCGAAACGGCGATGGATGTGTTTTATGAAGCGTTCGAGCT TAATTATTTCTCTGCTGTCCATTTCTCAAAGCTTGCACTGCCAGCGATGAAATCGGCAGGGAGAGGAACGATTATCAATA TTTCTTCTATATTTGGTCGTGAATCAGGTGGGAAAGCGACTTATAATAGCGCAAAAGCGGCGCTTATTAGTTTCACAAAA GCTCTTGCTGACGAGACGGCAAAACAAGGCATCCGCGTCAACAGCATAGCCCCGGGCTCGATACTTCATCCGACTGGAAA TTGGCAAAAACGCCTTGATGCCGATCCAGAGGGGATCACCGAATTTGTGAATCGTGACATTCCGGCCGGTCGGTTTGGAA CTCCAGAAGAAGTAGCAGATGTCGTCGTGTTTTTAGGATCAGATAAAGCGAGCTGGGTAACTGGAGCTACACTAGTGGTA GACGGCGGCCAGTCAAAATCGAATATATAG
Upstream 100 bases:
>100_bases CGGCGAATTGCCGCATCATAAAAGCGGAAGAACTAGAGCAGTATGCCTTTCCAGTTTCACAGCAAAAATTGTTGAATCAT TGTTTGGAGGAGGGATGGCT
Downstream 100 bases:
>100_bases GAAAAGCACACCGCCGAAACCGCGGTGTGTTTTTTAGATGCCAGGCTCTGTGTCGTCTTCATTCAGCAAGTTAATTTCTT TTATTTTGGCTTTTGTTTCT
Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Products: NA
Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]
Number of amino acids: Translated: 249; Mature: 249
Protein sequence:
>249_residues MNLGLTGKRVFVTGGTKGIGKAIANAFAAEGAKVAVCARVTEGIEGLLAGIQTISGDVTKAAERERMFAEASAAIGPIDI LVNNAGGSNGGAISETAMDVFYEAFELNYFSAVHFSKLALPAMKSAGRGTIINISSIFGRESGGKATYNSAKAALISFTK ALADETAKQGIRVNSIAPGSILHPTGNWQKRLDADPEGITEFVNRDIPAGRFGTPEEVADVVVFLGSDKASWVTGATLVV DGGQSKSNI
Sequences:
>Translated_249_residues MNLGLTGKRVFVTGGTKGIGKAIANAFAAEGAKVAVCARVTEGIEGLLAGIQTISGDVTKAAERERMFAEASAAIGPIDI LVNNAGGSNGGAISETAMDVFYEAFELNYFSAVHFSKLALPAMKSAGRGTIINISSIFGRESGGKATYNSAKAALISFTK ALADETAKQGIRVNSIAPGSILHPTGNWQKRLDADPEGITEFVNRDIPAGRFGTPEEVADVVVFLGSDKASWVTGATLVV DGGQSKSNI >Mature_249_residues MNLGLTGKRVFVTGGTKGIGKAIANAFAAEGAKVAVCARVTEGIEGLLAGIQTISGDVTKAAERERMFAEASAAIGPIDI LVNNAGGSNGGAISETAMDVFYEAFELNYFSAVHFSKLALPAMKSAGRGTIINISSIFGRESGGKATYNSAKAALISFTK ALADETAKQGIRVNSIAPGSILHPTGNWQKRLDADPEGITEFVNRDIPAGRFGTPEEVADVVVFLGSDKASWVTGATLVV DGGQSKSNI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=36.6935483870968, Blast_Score=127, Evalue=9e-30, Organism=Homo sapiens, GI40254992, Length=237, Percent_Identity=35.0210970464135, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=33.6, Blast_Score=124, Evalue=1e-28, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=35.4838709677419, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI59889578, Length=224, Percent_Identity=35.2678571428571, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=33.0677290836653, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=32.2709163346614, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30.7692307692308, Blast_Score=99, Evalue=4e-21, Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=37.0967741935484, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=31.9066147859922, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=30.6772908366534, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=34.2541436464088, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=34.375, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI4503301, Length=208, Percent_Identity=32.6923076923077, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI4503817, Length=238, Percent_Identity=26.4705882352941, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI157739938, Length=238, Percent_Identity=24.3697478991597, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=30.5, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI32455239, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI5031765, Length=186, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI109715829, Length=236, Percent_Identity=27.5423728813559, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI142976729, Length=221, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI7657478, Length=241, Percent_Identity=26.9709543568465, Blast_Score=65, Evalue=5e-11, Organism=Homo sapiens, GI150247226, Length=187, Percent_Identity=31.0160427807487, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1787335, Length=247, Percent_Identity=38.4615384615385, Blast_Score=134, Evalue=7e-33, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.5238095238095, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI1787905, Length=250, Percent_Identity=37.2, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=34.5528455284553, Blast_Score=104, Evalue=4e-24, Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=34.765625, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1790717, Length=251, Percent_Identity=30.6772908366534, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=31.4516129032258, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789378, Length=254, Percent_Identity=31.1023622047244, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=30.9803921568627, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=31.8181818181818, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=4e-19, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=26.5625, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=32.0224719101124, Blast_Score=68, Evalue=6e-13, Organism=Escherichia coli, GI1786701, Length=177, Percent_Identity=29.3785310734463, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=31.9391634980989, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=31.2741312741313, Blast_Score=122, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=34.2007434944238, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=32.0610687022901, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=35.9848484848485, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=32.6612903225806, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=35.408560311284, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=35.7429718875502, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=31.4176245210728, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=33.8403041825095, Blast_Score=113, Evalue=9e-26, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=32.6996197718631, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI25147288, Length=255, Percent_Identity=34.5098039215686, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=32.9268292682927, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=31.0344827586207, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17538480, Length=264, Percent_Identity=31.4393939393939, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=31.7164179104478, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.8548387096774, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=33.4630350194552, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=32.520325203252, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.0606060606061, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=29.3233082706767, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17536651, Length=259, Percent_Identity=33.5907335907336, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=30.188679245283, Blast_Score=97, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=29.3893129770992, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=30.5343511450382, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=28.030303030303, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=30.5660377358491, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17561272, Length=238, Percent_Identity=31.0924369747899, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17508651, Length=246, Percent_Identity=31.7073170731707, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI71997402, Length=185, Percent_Identity=30.2702702702703, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17570069, Length=200, Percent_Identity=30.5, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17508895, Length=188, Percent_Identity=27.6595744680851, Blast_Score=66, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=264, Percent_Identity=28.7878787878788, Blast_Score=80, Evalue=4e-16, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=29.6, Blast_Score=79, Evalue=9e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=31.5270935960591, Blast_Score=73, Evalue=3e-14, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=33.8582677165354, Blast_Score=130, Evalue=7e-31, Organism=Drosophila melanogaster, GI23397609, Length=248, Percent_Identity=36.6935483870968, Blast_Score=129, Evalue=1e-30, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=34.8, Blast_Score=124, Evalue=8e-29, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=34.5381526104418, Blast_Score=117, Evalue=6e-27, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=33.2, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=36.078431372549, Blast_Score=109, Evalue=1e-24, Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=34.9019607843137, Blast_Score=109, Evalue=2e-24, Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=32.6771653543307, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI21358495, Length=189, Percent_Identity=31.7460317460317, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI24580925, Length=193, Percent_Identity=33.160621761658, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI21356301, Length=192, Percent_Identity=30.2083333333333, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI21357673, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI17737361, Length=250, Percent_Identity=26.8, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24640442, Length=197, Percent_Identity=30.4568527918782, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI116007236, Length=189, Percent_Identity=25.9259259259259, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI24581726, Length=189, Percent_Identity=30.6878306878307, Blast_Score=67, Evalue=9e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011294 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.30 [H]
Molecular weight: Translated: 25698; Mature: 25698
Theoretical pI: Translated: 6.55; Mature: 6.55
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.0 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNLGLTGKRVFVTGGTKGIGKAIANAFAAEGAKVAVCARVTEGIEGLLAGIQTISGDVTK CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHH AAERERMFAEASAAIGPIDILVNNAGGSNGGAISETAMDVFYEAFELNYFSAVHFSKLAL HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH PAMKSAGRGTIINISSIFGRESGGKATYNSAKAALISFTKALADETAKQGIRVNSIAPGS HHHHCCCCCEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCC ILHPTGNWQKRLDADPEGITEFVNRDIPAGRFGTPEEVADVVVFLGSDKASWVTGATLVV EECCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHEEEEECCCCCCEEECEEEEE DGGQSKSNI ECCCCCCCC >Mature Secondary Structure MNLGLTGKRVFVTGGTKGIGKAIANAFAAEGAKVAVCARVTEGIEGLLAGIQTISGDVTK CCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHH AAERERMFAEASAAIGPIDILVNNAGGSNGGAISETAMDVFYEAFELNYFSAVHFSKLAL HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH PAMKSAGRGTIINISSIFGRESGGKATYNSAKAALISFTKALADETAKQGIRVNSIAPGS HHHHCCCCCEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCC ILHPTGNWQKRLDADPEGITEFVNRDIPAGRFGTPEEVADVVVFLGSDKASWVTGATLVV EECCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHEEEEECCCCCCEEECEEEEE DGGQSKSNI ECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA